國家衛生研究院 NHRI:Item 3990099045/6560
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    题名: Very small photoluminescent gold nanoparticles for multimodality biomedical imaging
    作者: Lai, SF;Chien, CC;Chen, WC;Chen, HH;Chen, YY;Wang, CL;Hwu, Y;Yang, CS;Chen, CY;Liang, KS;Petibois, C;Tan, HR;Tok, ES;Margaritondo, G
    贡献者: Center for Nanomedicine Research
    摘要: An original synthesis method based on X-ray irradiation produced gold nanoparticles (AuNPs) with two important properties for biomedical research: intense visible photoluminescence and very high accumulation in cancer cells. The nanoparticles, coated with MUA (11-mercaptoundecanoid acid), are very small (1.4 nm diameter); the above two properties are not present for even slightly larger sizes. The small MUA-AuNPs are non-cytotoxic (except for very high concentrations) and do not interfere with cancer cell proliferation. Multimodality imaging using visible light fluorescence and X-ray microscopy is demonstrated by tracing the nanoparticle-loaded tumor cells.
    日期: 2013-05
    關聯: Biotechnology Advances. 2013 May;31(3):362-368.
    Link to: http://dx.doi.org/10.1016/j.biotechadv.2012.05.005
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0734-9750&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000317441900002
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84875055833
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