國家衛生研究院 NHRI:Item 3990099045/6729

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Title:	Effects of dipeptidyl peptidase 4 inhibition with MK-0431 on syngeneic mouse islet transplantation
Authors:	Juang, JH;Kuo, CH;Liu, YH;Chen, CT
Contributors:	Institute of Biotechnology and Pharmaceutical Research
Abstract:	Dipeptidyl peptidase-4 (DPP-4) inhibitors increase circulating levels of active incretin hormones-glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) by blocking their degradation. In addition to their insulinotropic actions, GLP-1 and GIP also promote beta-cell proliferation and survival. The aim of this study was to test if DPP-4 inhibition with MK-0431 is beneficial for diabetic recipients with a marginal number of fresh islets.
Date:	2011-09
Relation:	Diabetologia. 2011 Sep;54(Suppl. 1):S181.
Link to:	http://dx.doi.org/10.1007/s00125-011-2276-4
JIF/Ranking 2023:	http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0012-186X&DestApp=IC2JCR
Cited Times(WOS):	https://www.webofscience.com/wos/woscc/full-record/WOS:000307671301084
Appears in Collections:	[Chiung-Tong Chen] Conference Papers/Meeting Abstract

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