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生技與藥物研究所
夏克山
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A convenient diels-alder approach t...
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Showing items 26-50 of 73. (3 Page(s) Totally)
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Date
Title
Relation
2016-01
Synthesis of (E)-oxindolylidene acetate using tandem palladium-catalyzed Heck and alkoxycarbonylation reactions
Organic and Biomolecular Chemistry. 2016 Jan;14(1):220-228.
2016-01
Important hydrogen bond networks in Indoleamine 2,3-Dioxygenase 1 (IDO1) inhibitor design revealed by crystal structures of imidazoleisoindole derivatives with IDO1
Journal of Medicinal Chemistry. 2016 Jan;59 (1):282-293.
2015-08-14
Studies on antibiotics active against resistant bacteria. Total synthesis of MRSA-active tetarimycin A and its analogues
Organic Letters. 2015 Aug 14;17(17):4248-4251.
2015-06-15
Synthesis and evaluation of 3-ylideneoxindole acetamides as potent anticancer agents
European Journal of Medicinal Chemistry. 2015 Jun 15;98:1-12.
2015-06-15
The total synthesis of retrojusticidin B, justicidin E, and helioxanthin
Journal of Organic Chemistry. 2015 Jun 15;80(13):6708-6714.
2015-05
A novel peripheral cannabinoid receptor 1 antagonist, BPR0912, reduces weight independently of food intake and modulates thermogenesis
Diabetes, Obesity and Metabolism. 2015 May;17(5):495-504.
2015-03
Stem cell mobilizers targeting chemokine receptor CXCR4: Renoprotective application in acute kidney injury
Journal of Medicinal Chemistry. 2015 Mar;58(5):2315-2325.
2015-02
Function-oriented development of CXCR4 antagonists as selective human immunodeficiency virus (HIV)-1 entry inhibitors
Journal of Medicinal Chemistry. 2015 Feb;58(3):1452-1465.
2014-10
Manganese(III)-catalyzed oxidative cyclization of aryl 1-cyanoalk-5-ynyl ketone systems: A convenient and general approach to cyclopenta[b]naphthalene derivatives
Advanced Synthesis and Catalysis. 2014 Oct;356(14-15):3025-3038.
2014-03
Double michael addition reactions of the nazarov reagent with 2-cyano-2-cycloalkenones: An alternative approach to cis-fused bicyclic systems
Synlett. 2014 Mar;25(4):543-546.
2013-11-13
Discovery of 1-(2,4-Dichlorophenyl)-N-(piperidin-1-yl)-4-((pyrrolidine-1-sulfonamido)methyl)-5 -(5-((4-(trifluoromethyl)phenyl)ethynyl)thiophene-2-yl)-1H-pyrazole-3-carboxamide as a novel peripherally restricted cannabinoid-1 receptor antagonist with significant weight-loss efficacy in diet-induced obese mice
Journal of Medicinal Chemistry. 2013 Nov 13;56(24):9920-9933.
2013-04
Palladium(0)/copper(I)-catalyzed tandem cyclization of aryl 1-cyanoalk-5-ynyl ketone system: Rapid assembly of cyclopenta[b]naphthalene and benzo[b]fluorene derivatives
Advanced Synthesis and Catalysis. 2013 Apr;355(7):1323-1337.
2012-12
Tandem cyclization of alpha-Cyano alpha-Alkynyl aryl ketones induced by tert-Butyl hydroperoxide and tetrabutylammonium iodide
Organic Letters. 2012 Dec;14(23):6024-6027.
2012-11-20
Beckmann rearrangement of ketoximes induced by phenyl dichlorophosphate at ambient temperature
Molecules. 2012 Nov 20;17(11):13662-13672.
2012-07
Induction of fatty acid oxidation resists weight gain, ameliorates hepatic steatosis and reduces cardiometabolic risk factors
International Journal of Obesity. 2012 Jul;36(7):999-1006.
2012-07
K2CO3/NaI-induced cyclization of omega-bromo alpha-cyano ketones: A new annulation approach for the formation of carbalkoxycyclohexane ring system
Synlett. 2012 Jul;23(11):1653-1656.
2012-05
Palladium(II) acetate mediated oxidative cyclization of omega-unsaturated alpha-cyano ketones for facile construction of methylenecyclohexane ring system
Organic & Biomolecular Chemistry. 2012 May;10(23):4609-4617.
2012-02
Discovery of novel stem cell mobilizers that target the CXCR4 receptor
ChemMedChem. 2012 Feb;7(2):209-212.
2011-07
Conia-ene annulation of the alpha-cyano Beta-TMS-capped alkynyl cycloalkanone system and its synthetic application
Organic and Biomolecular Chemistry. 2011 Jul;9(13):4778-4781.
2011-06
Hot topic: Opportunities and potential challenges for the treatment of metabolic syndrome
Current Topics In Medicinal Chemistry. 2011 Jun;11(12):1420.
2011-03-04
Autoxidative annulation cascade of the alpha-cyano beta-TMS-capped alkynyl cycloalkanone system
Organic Letters. 2011 Mar 4;13(5):896-899.
2010-10
Biphasic suppression of appetite by cannabinoid CB1 receptor antagonists with distinct functional activities
Pharmacological Research. 2010 Oct;62(4):337-343.
2010-09
Discovery of 1-(2,4-Dichlorophenyl)-4-ethyl-5-(5-(2-(4-(trifluoromethyl)phenyl)ethynyl)thiophe n-2-yl)-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide as a potential peripheral cannabinoid-1 receptor inverse agonist
ChemMedChem. 2010 Sep;5(9):1439-1443.
2010-08
Total synthesis of (-)-Isopisiferin: Confirmation of absolute configuration
Journal of Organic Chemistry. 2010 Aug;2010(22):4271-4275.
2010-06
General approach to 2,3-dibenzyl-gamma-butyrolactone lignans: application to the total synthesis of (+/-)-5 '-methoxyyatein, (+/-)-5 '-methoxyclusin, and (+/-)-4 '-hydroxycubebinone
European Journal of Organic Chemistry. 2010 Jun;2010(18):3473-3480.
Showing items 26-50 of 73. (3 Page(s) Totally)
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