國家衛生研究院 NHRI:
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    近3年内发表的文件:3(4.92%)
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    日期题名關聯
    2024-10-01 Hypoxia-induced long noncoding RNA HIF1A-AS2 regulates stability of MHC class I protein in head and neck cancer Cancer Immunology Research. 2024 Oct 01;12(10):1468-1484.
    2023-04 Targeting androgen receptor and the variants by an orally bioavailable Proteolysis Targeting Chimeras compound in castration resistant prostate cancer eBioMedicine. 2023 Apr;90:Article number 104500.
    2022-05-05 TEAD4 as an oncogene and a mitochondrial modulator Frontiers in Cell and Developmental Biology. 2022 May 5;10:Article number 890419.
    2021-12-14 Targeting mitochondrial OXPHOS and their regulatory signals in prostate cancers International Journal of Molecular Sciences. 2021 Dec 14;22(24):Article number 13435.
    2021-11 Human iPSC-derived neurons as a platform for deciphering the mechanisms behind brain aging Biomedicines. 2021 Nov;9(11):Article number 1635.
    2021-07-15 Arginine signaling and cancer metabolism Cancers. 2021 Jul 15;13(14):Article number 3541.
    2021-06-04 Arginine starvation elicits chromatin leakage and cGAS-STING activation via epigenetic silencing of metabolic and DNA-repair genes Theranostics. 2021 Jun 4;11(15):7527-7545.
    2021-05-05 Long non-coding rnas as functional codes for oral cancer: Translational potential, progress and promises International Journal of Molecular Sciences. 2021 May 5;22(9):Article number 4903.
    2021-04-23 Arginine is an epigenetic regulator targeting TEAD4 to modulate OXPHOS in prostate cancer cells Nature Communications. 2021 Apr 23;12:Article number 2398.
    2021-01-25 Genome-wide CRISPR/Cas9 knockout screening uncovers a novel inflammatory pathway critical for resistance to arginine-deprivation therapy Theranostics. 2021 Jan 25;11(8):3624-3641.
    2020-05 Muscle atrophy-related myotube-derived exosomal microRNA in neuronal dysfunction: Targeting both coding and long noncoding RNAs Aging Cell. 2020 May;19(5):Article number e13107.
    2020-05 Signaling in and out: Long-noncoding RNAs in tumor hypoxia Journal of Biomedical Science. 2020 May;27:Article number 59.
    2020-02 lncRNA UBA6-AS1 participates in the integrated stress response of breast cancer Cancer Research. 2020 Feb;80(4, Suppl.):Meeting Abstract P1-05-10.
    2020-01 Cancer-derived succinate promotes macrophage polarization and cancer metastasis via succinate receptor Molecular Cell. 2020 Jan;77(2):213-227.e5.
    2019-08-29 Dysregulation of cystathionine γ-lyase promotes prostate cancer progression and metastasis EMBO Reports. 2019 Aug 29:Article number e45986.
    2019-03-15 Mutations in the PKM2 exon-10 region are associated with reduced allostery and increased nuclear translocation Communications Biology. 2019 Mar 15;2:Article number 105.
    2019-01-25 KDM4B is a coactivator of c-Jun and involved in gastric carcinogenesis Cell Death and Disease. 2019 Jan 25;10(2):Article number 68.
    2019-01-03 KDM8/JMJD5 as a dual coactivator of AR and PKM2 integrates AR/EZH2 network and tumor metabolism in CRPC Oncogene. 2019 Jan 3;38(1):17-32.
    2018-10-01 HOTAIR is a REST-regulated lncRNA that promotes neuroendocrine differentiation in castration resistant prostate cancer Cancer Letters. 2018 Oct 1;433:43-52.
    2018-01-29 In vitro SUMOylation assay to study SUMO E3 ligase activity Journal of Visualized Experiments : JoVE. 2018 Jan 29;(131):Article number e56629.
    2017-11 EZH2-mediated upregulation of ROS1 oncogene promotes oral cancer metastasis Oncogene. 2017 Nov;36(47):6542-6554.
    2017-08-08 Long non-coding RNA and tumor hypoxia: New players ushered toward an old arena Journal of Biomedical Science. 2017 Aug 8;24:Article number 53.
    2017-06-22 Long noncoding RNA LncHIFCAR/MIR31HG is a HIF-1alpha co-activator driving oral cancer progression Nature Communications. 2017 Jun 22;8:Article number 15874.
    2017-03-03 REST is a crucial regulator for acquiring EMT-like and stemness phenotypes in hormone-refractory prostate cancer Scientific Reports. 2017 Mar 03;7:Article number 42795.
    2016-11 Silencing the epigenetic silencer KDM4A for TRAIL and DR5 simultaneous induction and antitumor therapy Cell Death and Differentiation. 2016 Nov;23(11):1886-1896.
    2016-09-13 KDM4A coactivates E2F1 to regulate the PDK-dependent metabolic switch between mitochondrial oxidation and glycolysis Cell Reports. 2016 Sep 13;16(11):3016-3027.
    2016-09 Metabolic stress-induced phosphorylation of KAP1 Ser473 blocks mitochondrial fusion in breast cancer cells Cancer Research. 2016 Sep;76(17):5006-5018.
    2016-06 HIF-1-alpha links mitochondrial perturbation to the dynamic acquisition of breast cancer tumorigenicity Oncotarget. 2016 Jun;7(23):34052-34069.
    2016-06 Rapid discovery of functional small molecule ligands against proteomic targets through library-against-library screening ACS Combinatorial Science. 2016 Jun;18(6):320-329.
    2016-05 REST reduction is essential for hypoxia-induced neuroendocrine differentiation of prostate cancer cells by activating autophagy signaling Oncotarget. 2016 May;7(18):26137-26151.
    2016-02-22 Guidelines for the use and interpretation of assays for monitoring autophagy [Erratum to: Autophagy. 2016 Jan 2;12(1):1-222.] Autophagy. 2016 Feb 22;12(2):443.
    2016-01-02 Guidelines for the use and interpretation of assays for monitoring autophagy Autophagy. 2016 Jan 2;12(1):1-222.
    2015-12-04 Non-coding RNAs in castration-resistant prostate cancer: Regulation of androgen receptor signaling and cancer metabolism International Journal of Molecular Sciences. 2015 Dec 4;16(12):28943-28978.
    2015-07-10 Akt3 promotes prostate cancer proliferation cells through regulation of Akt, B-Raf & TSC1/TSC2 Oncotarget. 2015 Jul 10;6(29):27097-27112.
    2015-04-30 Elevation of soluble guanylate cyclase suppresses proliferation and survival of human breast cancer cells PLoS ONE. 2015 Apr 30;10(4):Article number e0125518.
    2015-03 Caffeic acid phenethyl ester induced cell cycle arrest and growth inhibition in androgen-independent prostate cancer cells via regulation of Skp2, p53, p21Cip1 and p27Kip1 Oncotarget. 2015 Mar;6(9):6684-6707.
    2015-02 Chromatophagy: Autophagy goes nuclear and captures broken chromatin during arginine-starvation Autophagy. 2015 Feb;11(2):419-421.
    2014-12-30 A long noncoding RNA connects c-Myc to tumor metabolism Proceedings of the National Academy of Sciences of the United States of America. 2014 Dec 30;111(52):18697-18702.
    2014-12-01 AMACR amplification in myxofibrosarcomas: A mechanism of overexpression that promotes cell proliferation with therapeutic relevance Clinical Cancer Research. 2014 Dec 01;20(23):6141-6152.
    2014-11-04 Long non-coding RNA and epigenetic gene regulation of KSHV Viruses. 2014 Nov 4;6(11):4165-4177.
    2014-11 Downregulated MTAP expression in myxofibrosarcoma: A characterization of inactivating mechanisms, tumor suppressive function, and therapeutic relevance Oncotarget. 2014 Nov 30;5(22):11428-11441.
    2014-09-29 Sumo and KSHV replication Cancers. 2014 Sep 29;6(4):1905-1924.
    2014-09 Arginine starvation-associated atypical cellular death involves mitochondrial dysfunction, nuclear DNA leakage, and chromatin autophagy Proceedings of the National Academy of Sciences of the United States of America. 2014 Sep;11(39):14147-14152.
    2014-09 Targeting Btk/Etk of prostate cancer cells by a novel dual inhibitor Cell Death and Disease. 2014 Sep;5:Article number e1409.
    2014-07 KDM4B as a target for prostate cancer: Structural analysis and selective inhibition by a novel inhibitor Journal of Medicinal Chemistry. 2014 Jul;57(14):5975-5985.
    2014-05 miR-30 as a tumor suppressor connects EGF/Src signal to ERG and EMT Oncogene. 2014 May;33(19):2495-2503.
    2014-04 Arginine starvation impairs mitochondrial respiratory function in ASS1-Deficient breast cancer cells Science Signaling. 2014 Apr;7(319):Article number ra31.
    2014-02 A lytic viral long noncoding RNA modulates the function of a latent protein Journal of Virology. 2014 Feb;88(3):1843-1848.
    2014-02 Autophagy pathway is required for IL-6 induced neuroendocrine differentiation and chemoresistance of prostate cancer LNCaP cells PLoS ONE. 2014 Feb 14;9(2):Article number e88556.
    2014-01-07 JMJD5 regulates PKM2 nuclear translocation and reprograms HIF-1alpha-mediated glucose metabolism Proceedings of the National Academy of Sciences of the United States of America. 2014 Jan 7;111(1):279-284.

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