| 2023-11 |
Lysosomal-targeted doxorubicin delivery using RBC-derived vesicles to overcome drug-resistant cancer through mitochondrial-dependent cell death |
Pharmacological Research. 2023 Nov;197:Article number 106945. |
 |
| 2023-03-28 |
Synthesis and structure–activity relationship of salvinal derivatives as potent microtubule inhibitors |
International Journal of Molecular Sciences. 2023 Mar 28;24(7):Article number 6386. |
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| 2023-02-28 |
How to deal with frenemy NRF2: Targeting NRF2 for chemoprevention and cancer therapy |
Journal of Food and Drug Analysis. 2023 Feb 28;31(3):387-407. |
|
| 2023-01 |
Two new chromones and a new coumarin from the fruit of Cnidium monnieri (L.) Cusson |
Natural Product Research. 2023 Jan;37(1):47-55. |
|
| 2022-02-05 |
Discovery and development of a novel N-(3-bromophenyl)-{[(phenylcarbamoyl)amino]methyl}-N-hydroxythiophene-2-carboximidamide indoleamine 2,3-dioxygenase inhibitor using knowledge-based drug design |
European Journal of Medicinal Chemistry. 2022 Feb 5;229:Article number 114043. |
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| 2022-01-17 |
Pilot study: Nutritional and preclinical safety investigation of fermented hispidin-enriched sanghuangporus sanghuang mycelia: A promising functional food material to improve sleep |
Frontiers in Nutrition. 2022 Jan 17;8:Article number 788965. |
|
| 2021-12-14 |
A novel NRF2/ARE inhibitor gossypol induces cytotoxicity and sensitizes chemotherapy responses in chemo-refractory cancer cells |
Journal of Food and Drug Analysis. 2021 Dec 14;29(4):638-652. |
|
| 2021-10-29 |
Type-3 hyaluronan synthase attenuates tumor cells invasion in human mammary parenchymal tissues |
Molecules. 2021 Oct 29;26(21):Article number 6548. |
|
| 2021-08-12 |
Xanthine derivatives reveal an allosteric binding site in methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) |
Journal of Medicinal Chemistry. 2021 Aug 12;64(15):11288-11301. |
|
| 2021-03-15 |
Tea polyphenol epigallocatechin-3-gallate inhibits cell proliferation in a patient-derived triple-negative breast cancer xenograft mouse model via inhibition of proline-dehydrogenase-induced effects |
Journal of Food and Drug Analysis. 2021 Mar 15;29(1):113-127. |
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| 2021-03-11 |
c-MYC-directed NRF2 drives malignant progression of head and neck cancer via glucose-6-phosphate dehydrogenase and transketolase activation |
Theranostics. 2021 Mar 11;11(11):5232-5247. |
|
| 2020-08 |
Two new diprenylated flavanones from Derris laxiflora Benth |
Natural Product Research. 2020 Aug;34(15):2101-2108. |
|
| 2020-04-02 |
MiR-30a and miR-379 modulate retinoic acid pathway by targeting DNA methyltransferase 3B in oral cancer |
Journal of Biomedical Science. 2020 Apr 2;27:Article number 46. |
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| 2020-02-10 |
Unique sulfur-aromatic interactions contribute to the binding of potent imidazothiazole indoleamine 2,3-Dioxygenase inhibitors |
Journal of Medicinal Chemistry. 2020 Feb 10;63(4):1642-1659. |
|
| 2019-12-24 |
ERK activation modulates cancer stemness and motility of a novel mouse oral squamous cell carcinoma cell line |
Cancers. 2019 Dec 24;12(1):Article number 61. |
|
| 2019-12 |
Identification of a multitargeted tyrosine kinase inhibitor for the treatment of gastrointestinal stromal tumors and acute myeloid leukemia |
Journal of Medicinal Chemistry. 2019 Dec;62(24):11135-11150. |
|
| 2019-08 |
Melatonin promotes neuroblastoma cell differentiation by activating hyaluronan synthase 3-induced mitophagy |
Cancer Medicine. 2019 Aug;8(10):4821-4835. |
|
| 2018-12 |
Ubiquitin-conjugating enzyme E2 B regulates the ubiquitination of O(6)-methylguanine-DNA methyltransferase and BCNU sensitivity in human nasopharyngeal carcinoma cells |
Biochemical Pharmacology. 2018 Dec;158:327-338. |
|
| 2018-06-15 |
2-Aroylquinoline-5,8-diones as potent anticancer agents displaying tubulin and heat shock protein 90 (HSP90) inhibition [Erratum: Organic and Biomolecular Chemistry. 2016 Jan;14(2):716-723.] |
Organic and biomolecular chemistry. 2018 Jun 15;16:4734. |
|
| 2018-04 |
4-Bromophenylhydrazinyl benzenesulfonylphenylureas as indoleamine 2,3-dioxygenase inhibitors with in vivo target inhibition and anti-tumor efficacy |
Bioorganic Chemistry. 2018 Apr;77:600-607. |
|
| 2017-12 |
Enhanced B-Raf-mediated NRF2 gene transcription and HATs-mediated NRF2 protein acetylation contributes to ABCC1-mediated chemoresistance and glutathione-mediated survival in acquired topoisomerase II poison-resistant cancer cells |
Free Radical Biology and Medicine. 2017 Dec;113:505-518. |
|
| 2017-08 |
Hypoxia-induced downregulation of DUSP-2 phosphatase drives colon cancer stemness |
Cancer Research. 2017 Aug;77(16):4305-4316. |
|
| 2017-07 |
Drug repurposing for chronic myeloid leukemia: In silico and in vitro investigation of DrugBank database for allosteric Bcr-Abl inhibitors |
Journal of Biomolecular Structure and Dynamics. 2017 Jun;35(8):1833-1848. |
|
| 2017-07 |
Design, synthesis, and evaluation of thiazolidine-2,4-dione derivatives as a novel class of glutaminase inhibitors |
Journal of Medicinal Chemistry. 2017 Jul;60(13):5599-5612. |
|
| 2016-12 |
Discovery of BPR1K871, a quinazoline based, multi-kinase inhibitor for the treatment of AML and solid tumors: Rational design, synthesis, in vitro and in vivo evaluation |
Oncotarget. 2016 Dec;7(52):86239-86256. |
|
| 2016-08 |
Desferal regulates hCtr1 and transferrin receptor expression through Sp1 and exhibits synergistic cytotoxicity with platinum drugs in oxaliplatin-resistant human cervical cancer cells in vitro and in vivo |
Oncotarget. 2016 Aug;7(31):49310-49321. |
|
| 2016-07-01 |
MPT0B098, a microtubule inhibitor, suppresses JAK2/STAT3 signaling pathway through modulation of SOCS3 stability in oral squamous cell carcinoma |
PLoS ONE. 2016 Jul 1;11(7):Article number e0158440. |
|
| 2016-01 |
2-Aroylquinoline-5,8-diones as potent anticancer agents displaying tubulin and heat shock protein 90 (HSP90) inhibition |
Organic and Biomolecular Chemistry. 2016 Jan;14(2):716-723. |
|
| 2016-01 |
Phenyl benzenesulfonylhydrazides exhibit selective Indoleamine 2,3-Dioxygenase inhibition with potent in vivo pharmacodynamic activity and antitumor efficacy |
Journal of Medicinal Chemistry. 2016 Jan;59(1):419-430. |
|
| 2015-12 |
Novel oxime-bearing coumarin derivatives act as potent Nrf2/ARE activators in vitro and in mouse model |
European Journal of Medicinal Chemistry. 2015 Dec;106:60-74. |
|
| 2015-09 |
O6-Methylguanine DNA methyltransferase repairs platinum-DNA adducts following cisplatin treatment and predicts prognoses of nasopharyngeal carcinoma |
International Journal of Cancer. 2015 Sep;137(6):1291-1305. |
|
| 2015-08 |
Antimitotic and antivascular activity of heteroaroyl-2-hydroxy-3,4,5-trimethoxybenzenes |
Bioorganic and Medicinal Chemistry. 2015 Aug;23(15):4230-4236. |
|
| 2015-08 |
Novel Nrf2/ARE activator, trans-coniferylaldehyde, induces a HO-1-mediated defense mechanism through a dual p38alpha/MAPKAPK-2 and PK-N3 signaling pathway |
Chemical Research in Toxicology. 2015 Aug ;28(9):1681-1692. |
|
| 2015-05 |
Mechanistic basis of a combination D-penicillamine and platinum drugs synergistically inhibits tumor growth in oxaliplatin-resistant human cervical cancer cells in vitro and in vivo |
Biochemical Pharmacology. 2015 May;95(1):28-37. |
|
| 2015-01 |
Two new labdane-type diterpene acids from the wood of cunninghamia konishii |
Helvetica Chimica Acta. 2015 Jan;98(1):123-127. |
|
| 2014-05 |
Azaindolylsulfonamides, with a more selective inhibitory effect on histone deacetylase 6 activity, exhibit antitumor activity in colorectal cancer HCT116 cells |
Journal of Medicinal Chemistry. 2014 May;57(10):4009-4022. |
|
| 2014-04 |
Antimitotic and vascular disrupting agents: 2-hydroxy-3,4,5-trimethoxybenzophenones |
European Journal of Medicinal Chemistry. 2014 Apr 22;77(2):306-314. |
|
| 2013-12 |
Diterpenoids from the wood of Cunninghamia konishii |
Helvetica Chimica Acta. 2013 Dec;96(12):2282-2287. |
|
| 2013-10 |
Histone deacetylase inhibition improved cardiac functions with direct antifibrotic activity in heart failure |
International Journal of Cardiology. 2013 Oct;168(4):4178-4183. |
|
| 2013-10 |
Gene expression profiling for analysis acquired oxaliplatin resistant factors in human gastric carcinoma TSGH-S3 cells: The role of IL-6 signaling and Nrf2/AKR1C axis identification |
Biochemical Pharmacology. 2013 Oct;86(7):872-887. |
|
| 2013-09 |
Furanylazaindoles: Potent anticancer agents in vitro and in vivo |
Journal of Medicinal Chemistry. 2013 Sep;56(20):8008-8018. |
|
| 2013-06 |
Heart failure and angiotensin II modulate atrial Pitx2c promotor methylation |
Clinical and Experimental Pharmacology and Physiology. 2013 Jun;40(6):379-384. |
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