邻近类别 會議論文/會議摘要 [14/24] 專利 [0/8] 类别统计 近3年内发表的文件:18(15.00%) 含全文笔数:119(99.17%) 文件下载次数统计 下载大于0次:119(100.00%) 下载大于100次:114(95.80%) 全文下载总次数:72631(90.20%) 最后更新时间: 2024-12-04 03:06 上传排行 数据加载中..... 下载排行 数据加载中..... 最近上传 DBPR116, a prodrug of BPRMU191, in ... Discovery of a mu-opioid receptor m... Development of a humanized antibody... Discovery of dual MER/AXL kinase in... Discovery of a long half-life AURKA... A dual nociceptin and mu opioid rec... Discovery of tetrasubstituted thiop... Development of furanopyrimidine-bas... 2,6-Difluorobenzamide derivatives a... Protective effect of CXCR4 antagoni...

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显示项目76-100 / 120. (共5页) << < 1 2 3 4 5 > >> 每页显示[10|25|50]项目

日期	题名	關聯
2012-09	Synthesis and biological evaluation of novel C-indolylxylosides as sodium-dependent glucose co-transporter 2 inhibitors	European Journal of Medicinal Chemistry. 2012 Sep;55:32-38.
2012-09	Anti-influenza drug discovery: Identification of an orally bioavailable quinoline derivative through activity- and property-guided lead optimization	ChemMedChem. 2012 Sep;7(9):1546-1550.
2012-06-07	3-Phenyl-1H-5-pyrazolylamine-based derivatives as potent and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3)	Bioorganic and Medicinal Chemistry Letters. 2012 Jun 7;22(14):4654-4659.
2012-06	Effects of Bu-Zhong-Yi-Qi-Tang on hepatic drug-metabolizing enzymes and plasma tolbutamide concentration in rats	Journal of Ethnopharmacology. 2012 Jun;142(1):121-128.
2012-04	Synthesis and biological evaluation of 1-Arylsulfonyl-5-(N-hydroxyacrylamide)indoles as potent histone deacetylase inhibitors with antitumor activity in vivo	Journal of Medicinal Chemistry. 2012 Apr;55(8):3777-3791.
2012-02-01	Kinetics and tissue distribution of neutron-activated zinc oxide nanoparticles and zinc nitrate in mice: Effects of size and particulate nature	Nanotechnology. 2012 Feb 1;23(8):Article number 085102.
2012-01	Resistance analysis and characterization of a thiazole analogue, BP008, as a potent hepatitis C virus NS5A inhibitor	Antimicrobial Agents and Chemotherapy. 2012 Jan;56(1):44-53.
2012-01	BPR1J-097, a novel FLT3 kinase inhibitor, exerts potent inhibitory activity against AML	British Journal of Cancer. 2012 Jan;106(3):475-481.
2011-08	BPR1K653, a novel aurora kinase inhibitor, exhibits potent anti-proliferative activity in MDR1 (P-gp170)-mediated multidrug-resistant cancer cells	PLoS ONE. 2011 Aug;6(8):Article number e23485.
2011-07	Discovery and evaluation of 3-phenyl-1H-5-pyrazolylamine-based derivatives as potent, selective and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3)	Bioorganic and Medicinal Chemistry. 2011 Jul;19(14):4173-4182 .
2011-04-28	Scaffold-hopping strategy: Synthesis and biological evaluation of 5,6-Fused bicyclic heteroaromatics to identify orally bioavailable anticancer agents	Journal of Medicinal Chemistry. 2011 Apr 28;54(8):3076-3080.
2011-03	Comparative tissue distributions of cadmium chloride and cadmium-based quantum dot 705 in mice: Safety implications and applications	Nanotoxicology. 2011 Mar;5(1):91-97.
2011-03	Effect of shengmai san on insulin resistance, tumor necrosis factor-alpha and oxidative stress in rats fed on a high-fat diet	Journal of Food and Drug Analysis. 2011 Mar;19(1):40-48.
2011-01-13	Discovery of novel N -Beta- d -Xylosylindole derivatives as sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors for the management of hyperglycemia in diabetes	Journal of Medicinal Chemistry. 2011 Jan 13;54(1):166-178.
2011-01	BPR0C261 is a novel orally active antitumor agent with antimitotic and anti-angiogenic activities	Cancer Science. 2011 Jan;102(1):182-191.
2010-11	Identification of phenanthroindolizines and phenanthroquinolizidines as novel potent anti-coronaviral agents for porcine enteropathogenic coronavirus transmissible gastroenteritis virus and human severe acute respiratory syndrome coronavirus	Antiviral Research. 2010 Nov;88(2):160-168.
2010-10-28	Design and synthesis of tetrahydropyridothieno[2,3-d]pyrimidine scaffold based epidermal growth factor receptor (EGFR) kinase inhibitors: the role of side chain chirality and michael acceptor group for maximal potency	Journal of Medicinal Chemistry. 2010 Oct 28;53(20):7316-7326.
2010-10	Biphasic suppression of appetite by cannabinoid CB1 receptor antagonists with distinct functional activities	Pharmacological Research. 2010 Oct;62(4):337-343.
2010-09-01	Synthesis, activity, and pharmacokinetic properties of a series of conformationally-restricted thiourea analogs as novel hepatitis C virus inhibitors	Bioorganic and Medicinal Chemistry. 2010 Sep ;18(17):6414-6421.
2010-09	Discovery of 1-(2,4-Dichlorophenyl)-4-ethyl-5-(5-(2-(4-(trifluoromethyl)phenyl)ethynyl)thiophe n-2-yl)-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide as a potential peripheral cannabinoid-1 receptor inverse agonist	ChemMedChem. 2010 Sep;5(9):1439-1443.
2010-08	Substituted 4-carboxymethylpyroglutamic acid diamides as potent and selective inhibitors of fibroblast activation protein	Journal of Medicinal Chemistry. 2010 Aug;53(18):6572-6583.
2010-07	Antiangiogenic Activities and Cisplatin-combined Antitumor Activities of BPR0L075	Anticancer Research. 2010 Jul;30(7):2813-2822.
2010-06-15	(2S,4S)-1-[2-(1,1-Dimethyl-3-oxo-3-pyrrolidin-1-yl-propylamino)acetyl]-4-fluoro-pyrrolidine-2-carbonitrile: A potent, selective, and orally bioavailable dipeptide-derived inhibitor of dipeptidyl peptidase IV	Bioorganic and Medicinal Chemistry Letters. 2010 Jun 15;20(12):3596-3600.
2010-02	Antitumor activities and pharmacokinetics of silatecans DB-67 and DB-91	Pharmacological Research. 2010 Feb;61(2):108-115.
2009-08-13	Synthesis and evaluation of 3-aroylindoles as anticancer agents: Metabolite approach	Journal of Medicinal Chemistry. 2009 Aug 13;52(15):4941-4945.

显示项目76-100 / 120. (共5页) << < 1 2 3 4 5 > >> 每页显示[10|25|50]项目