國家衛生研究院 NHRI:
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    最後更新時間: 2024-12-01 02:01


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    日期題名關聯
    2024-01-23 Decrypting orphan GPCR drug discovery via multitask learning Journal of Cheminformatics. 2024 Jan 23;16:Article number 10.
    2023-07-20 Natural fucoidans inhibit coronaviruses by targeting viral spike protein and host cell furin Biochemical Pharmacology. 2023 Jul 20;215:Article number 115688.
    2023-01 Modulating the affinity and signaling bias of cannabinoid receptor 1 antagonists Bioorganic Chemistry. 2023 Jan;130:Article number 106236.
    2022-02-05 Discovery and development of a novel N-(3-bromophenyl)-{[(phenylcarbamoyl)amino]methyl}-N-hydroxythiophene-2-carboximidamide indoleamine 2,3-dioxygenase inhibitor using knowledge-based drug design European Journal of Medicinal Chemistry. 2022 Feb 5;229:Article number 114043.
    2020-02-10 Unique sulfur-aromatic interactions contribute to the binding of potent imidazothiazole indoleamine 2,3-Dioxygenase inhibitors Journal of Medicinal Chemistry. 2020 Feb 10;63(4):1642-1659.
    2019-08 A structure-function approach identifies L-PGDS as a mediator responsible for glucocorticoid-induced leptin expression in adipocytes Biochemical Pharmacology. 2019 Aug;166:203-211.
    2019-01-01 Fluorine-18 isotope labeling for positron emission tomography imaging. Direct evidence for DBPR211 as a peripherally restricted CB1 inverse agonist Bioorganic and Medicinal Chemistry. 2019 Jan 1;27(1):216-223.
    2018-10-06 Median nerve stimulation induces analgesia via orexin-initiated endocannabinoid disinhibition in the periaqueductal gray Proceedings of the National Academy of Sciences of the United States of America. 2018 Nov;115(45):E10720-E10729.
    2018-08-21 DUSP6 mediates T cell receptor-engaged glycolysis and restrains TFH cell differentiation Proceedings of the National Academy of Sciences of the United States of America. 2018 Aug 21;115(34):E8027-E8036.
    2018-04 4-Bromophenylhydrazinyl benzenesulfonylphenylureas as indoleamine 2,3-dioxygenase inhibitors with in vivo target inhibition and anti-tumor efficacy Bioorganic Chemistry. 2018 Apr;77:600-607.

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