國家衛生研究院 NHRI:Item 3990099045/8914
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    Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/8914


    Title: Polyvalent chimeric rubella virus-based vaccines
    Authors: Chow, YH;Sia, CDY;Chong, PCS;Hsiao, KN
    Contributors: Division of Vaccine Research and Development
    Abstract: A chimeric viral particle that comprises a RV fusion gene is disclosed. The RV fusion gene comprises a first nucleotide sequence encoding a RV that is devoid of RV E1 protein, and a second nucleotide sequence that linked in translation frame to the first nucleotide sequence and encodes a humoral immunogenic viral protein. The chimeric viral particle is free of RV E1 protein-encoding gene. A virus packaging cell that generates the chimeric viral particle comprising a RV fusion gene and an isolated expression vector comprising a RV fusion gene linked in translation frame to a promoter are also disclosed.
    Date: 2013-06-11
    Relation: US8460680B2/2013-06-11
    Link to: http://v3.espacenet.com/publicationDetails/biblio?CC=US&NR=8460680&KC=B2
    Appears in Collections:[Joe Yen-Hung Chow] Patents
    [Charles Dwo-Yuan Sia(2006-2014)] Patents
    [Pele Choi-Sing Chong] Patents

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