國家衛生研究院 NHRI:Item 3990099045/8914
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    题名: Polyvalent chimeric rubella virus-based vaccines
    作者: Chow, YH;Sia, CDY;Chong, PCS;Hsiao, KN
    贡献者: Division of Vaccine Research and Development
    摘要: A chimeric viral particle that comprises a RV fusion gene is disclosed. The RV fusion gene comprises a first nucleotide sequence encoding a RV that is devoid of RV E1 protein, and a second nucleotide sequence that linked in translation frame to the first nucleotide sequence and encodes a humoral immunogenic viral protein. The chimeric viral particle is free of RV E1 protein-encoding gene. A virus packaging cell that generates the chimeric viral particle comprising a RV fusion gene and an isolated expression vector comprising a RV fusion gene linked in translation frame to a promoter are also disclosed.
    日期: 2013-06-11
    關聯: US8460680B2/2013-06-11
    Link to: http://v3.espacenet.com/publicationDetails/biblio?CC=US&NR=8460680&KC=B2
    显示于类别:[周彥宏] 專利
    [謝鐸源(2006-2014)] 專利
    [莊再成] 專利

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