| Abstract: | This invention features, among others, a pyrazolopyrimidine compound of formula (A): | | A is (CH | | 2 | ) | q | --CHR | a | R | b | ; each of R | 1 | and R | 2 | , independently, is hydrogen, halogen, cyano, nitro, or alkyl; or R | 1 | and R | 2 | taken together is (CH | 2 | ) | r | ; each of R | 3 | and R | 4 | , independently, is hydrogen, halogen, cyano, nitro, or alkyl; each of R | 5 | , R | a | , and R | b | , independently, is aryl, aralkyl, or heteroaryl, optionally substituted with halogen, cyano, nitro, alkyl, aryl, aralkyl, heteroaryl, OR, O(O)CR, C(O)R, C(O)OR, C(O)NRR', SR, S(O)R, S(O)OR, NRR', NR(O)CR', NRC(O) OR', or NRC(O)NR'R" each of m, n, o, p, and r, independently, is 0 or 1, and q is 0, 1, or 2; in which each of R, R', and R", independently, is hydrogen or alkyl, provided that the sum of m, n, o, and p is 1, 2, 3, or 4. | This invention features, among others, a pyrazolopyrimidine compound of formula (A):A is (CH2)q-CHR<a>R<b>; each of R1 and R2, independently, is hydrogen, halogen, cyano, nitro, or alkyl; or R1 and R2 taken together is (CH2)r; each of R3 and R4, independently, is hydrogen, halogen, cyano, nitro, or alkyl; each of R5, R<a>, and R<b>, independently, is aryl, aralkyl, or heteroaryl, optionally substituted with halogen, cyano, nitro, alkyl, aryl, aralkyl, heteroaryl, OR, O(O)CR, C(O)R, C(O)OR, C(O)NRR', SR, S(O)R, S(O)OR, NRR', NR(O)CR', NRC(O)OR', or NRC(O)NR'R''; each of m, n, o, p, and r, independently, is 0 or 1, and q is 0, 1, or 2; in which each of R, R', and R'', independently, is hydrogen or alkyl, provided that the sum of m, n, o, and p is 1, 2, 3, or 4. |
