English  |  正體中文  |  简体中文  |  Items with full text/Total items : 12145/12927 (94%)
Visitors : 911148      Online Users : 950
RC Version 6.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
Scope Tips:
  • please add "double quotation mark" for query phrases to get precise results
  • please goto advance search for comprehansive author search
    •  Adv. Search
    Home ‧ Login ‧ Upload ‧ Help ‧ About ‧ Administer Goto mobile version


    Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/9811


    Title: Association of short-term exposure to fine particulate matter and nitrogen dioxide with acute cardiovascular effects
    Authors: Wu, CF;Shen, FH;Li, YR;Tsao, TM;Tsai, MJ;Chen, CC;Hwang, JS;Hsu, SHJ;Chao, H;Chuang, KJ;Chou, CCK;Wang, YN;Ho, CC;Su, TC
    Contributors: Division of Biostatistics and Bioinformatics
    Abstract: This study evaluated whether exposure to fine particulate matter (PM2.5) and nitrogen dioxide (NO2) is associated with cardiovascular effects by examining a panel of 89 healthy subjects in Taipei, Taiwan. The subjects received two health examinations approximately 8 months apart in 2013. Brachial–ankle pulse wave velocity (baPWV), a physiological indicator of arterial stiffness, and high-sensitivity C-reactive protein (hsCRP), a biomarker of vascular inflammations, were measured during each examination. Two exposure assessment methods were used for estimating the subjects' exposure to PM2.5 and NO2. The first method involved constructing daily land use regression (LUR) models according to measurements collected at ambient air quality monitoring stations. The second method required combining the LUR estimates with indoor monitoring data at the workplace of the subjects. Linear mixed models were used to examine the association between the exposure estimates and health outcomes. The results showed that a 10-μg/m3 increase in PM2.5 concentration at a 1-day lag was associated with 2.1% (95% confidence interval: 0.7%–3.6%) and 2.4% (0.8%–4.0%) increases in baPWV based on the two exposure assessment methods, whereas no significant association was observed for NO2. The significant effects of PM2.5 remained in the two-pollutant models. By contrast, NO2, but not PM2.5, was significantly associated with increased hsCRP levels (16.0%–37.3% in single-pollutant models and 26.4%–44.6% in two-pollutant models, per 10-ppb increase in NO2). In conclusion, arterial stiffness might be more sensitive to short-term PM2.5 exposure than is inflammation.
    Date: 2016-11
    Relation: Science of the Total Environment. 2016 Nov;569-570:300-305.
    Link to: http://dx.doi.org/10.1016/j.scitotenv.2016.06.084
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0048-9697&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000382269000032
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84975885818
    Appears in Collections:[陳主智] 期刊論文

    Files in This Item:

    File Description SizeFormat
    SDO0048969716312578.pdf536KbAdobe PDF487View/Open


    All items in NHRI are protected by copyright, with all rights reserved.

    Related Items in TAIR

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - Feedback