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生技與藥物研究所
陳炯東
--期刊論文
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Natural fucoidans inhibit coronavir...
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DBPR116, a prodrug of BPRMU191, in ...
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Showing items 26-50 of 160. (7 Page(s) Totally)
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Date
Title
Relation
2021-10-01
Engineering nano- and microparticles as oral delivery vehicles to promote intestinal lymphatic drug transport
Advanced Materials. 2021 Oct 01;201:Article number 2104139.
2021-08-13
Remdesivir and cyclosporine synergistically inhibit the human coronaviruses OC43 and SARS-CoV-2
Frontiers in Pharmacology. 2021 Aug 13;12:Article number 706901.
2021-08-01
DBPR108, a novel dipeptidyl peptidase-4 inhibitor with antihyperglycemic activity
Life Sciences. 2021 Aug 1;278:Article number 119574.
2021-08
A noninvasive gut-to-brain oral drug delivery system for treating brain tumors
Advanced Materials. 2021 Aug;33(34):Article number e2100701.
2021-05-19
Discovery and synthesis of a pyrimidine-based aurora kinase inhibitor to reduce levels of MYC oncoproteins
Journal of Medicinal Chemistry. 2021 May 19;64(11):7312-7330.
2021-01
BPRDP056, a novel small molecule drug conjugate specifically targeting phosphatidylserine for cancer therapy
Translational Oncology. 2021 Jan;14(1):Article number 100897.
2021-01
Potent and orally active purine-based fetal hemoglobin inducers for treating Beta-thalassemia and sickle cell disease
European Journal of Medicinal Chemistry. 2021 Jan;209:Article number 112938.
2020-12-14
Inhibition of SARS-CoV-2 by highly potent broad-spectrum anti-coronaviral tylophorine-based derivatives
Frontiers in Pharmacology. 2020 Dec 14;11:Article number 606097.
2020-11
Molecular profiling of afatinib-resistant non-small cell lung cancer cells in vivo derived from mice
Pharmacological Research. 2020 Nov;161:Article number 105183.
2020-10-08
Comparative study between deep learning and QSAR classifications for TNBC inhibitors and novel GPCR agonist discovery
Scientific Reports. 2020 Oct 8;10:Article number 16771.
2020-10
A bubble bursting-mediated oral drug delivery system that enables concurrent delivery of lipophilic and hydrophilic chemotherapeutics for treating pancreatic tumors in rats
Biomaterials. 2020 Oct;255:Article number 120157.
2020-08-20
Discovery of M protease inhibitors encoded by SARS-CoV-2
Antimicrobial Agents and Chemotherapy. 2020 Aug 20;64(9):e00872-20.
2020-08
Artificial intelligence approach fighting COVID-19 with repurposing drugs
Biomedical Journal. 2020 Aug;43(4):355-362.
2020-08
Repurposing old drugs as antiviral agents for coronaviruses
Biomedical Journal. 2020 Aug;43(4):368-374.
2020-02-18
Impacts of intralipid on nanodrug abraxane therapy and on the innate immune system
Scientific Reports. 2020 Feb 18;10:Article number 2838.
2019-12
A novel flavivirus entry inhibitor, BP34610, discovered through high-throughput screening with dengue reporter viruses
Antiviral Research. 2019 Dec;172:Article number 104636.
2019-12
Identification of a multitargeted tyrosine kinase inhibitor for the treatment of gastrointestinal stromal tumors and acute myeloid leukemia
Journal of Medicinal Chemistry. 2019 Dec;62(24):11135-11150.
2019-11-27
Discovery of a furanopyrimidine-based epidermal growth factor receptor inhibitor (DBPR112) as a clinical candidate for the treatment of non-small cell lung cancer
Journal of Medicinal Chemistry. 2019 Nov 27;62(22):10108-10123.
2019-09
Effects of boschnaloside from Boschniakia rossica on dysglycemia and islet dysfunction in severely diabetic mice through modulating the action of glucagon-like peptide-1
Phytomedicine. 2019 Sep;62:Article number 152946.
2019-08-27
A dengue virus type 2 (DENV-2) NS4B-interacting host factor, SERP1, reduces DENV-2 production by suppressing viral RNA replication
Viruses. 2019 Aug 27;11(9):Article number 787.
2019-07-11
Linker optimization and therapeutic evaluation of phosphatidylserine-targeting zinc dipicolylamine-based drug conjugates
Journal of Medicinal Chemistry. 2019 Jul 11;62(13):6047-6062.
2019-07
Citronellol induces necroptosis of human lung cancer cells via TNF-alpha pathway and reactive oxygen species accumulation
In Vivo. 2019 Jul-Aug;33(4):1193-1201.
2019-06-15
Strategies for improving diabetic therapy via alternative administration routes that involve stimuli-responsive insulin-delivering systems
Advanced Drug Delivery Reviews. 2019 Jan 15;139(SI):71-82.
2019-04-10
Discovery of Conformational Control Inhibitors Switching off the Activated c-KIT and Targeting a Broad Range of Clinically Relevant c-KIT Mutants
Journal of Medicinal Chemistry. 2019 Apr 10;62(8):3940-3957.
2019-04-01
A novel, potent, and orally bioavailable thiazole HCV NS5A inhibitor for the treatment of hepatitis C virus
European Journal of Medicinal Chemistry. 2019 Apr 1;167:245-268.
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