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    Items for Author "陳新" 

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    Showing 70 items.

    Collection Date Title Relation Bitstream
    [伍素瑩] 期刊論文 2009-10 (1,3-Diphenyl-1H-pyrazol-4-yl)-methylamine analogues as inhibitors of dipeptidyl peptidases -
    [陳新(2002-2015)] 期刊論文 2010-06-15 (2S,4S)-1-[2-(1,1-Dimethyl-3-oxo-3-pyrrolidin-1-yl-propylamino)acetyl]-4-fluoro-pyrrolidine-2-carbonitrile: A potent, selective, and orally bioavailable dipeptide-derived inhibitor of dipeptidyl peptidase IV -
    [蔣維棠] 期刊論文 2006-01-12 2-[3-[2-[(2S)-2-cyano-1-pyrrolidinyl]-2-oxoethylamino]-3-methyl-1-oxobutyl]-1,2,3,4-tetrahydroisoquinoline: A potent, selective, and orally bioavailable dipeptide-derived inhibitor of dipeptidyl peptidase IV -
    [蔣維棠] 期刊論文 2007-03-01 3-[2-((2S)-2-Cyano-pyrrolidin-1-yl)-2-oxo-ethylamino]-3-methyl-butyramide analogues as selective DPP-IV inhibitors for the treatment of type-II diabetes -
    [陳新(2002-2015)] 期刊論文 2009-09-03 Ankrd17, an ubiquitously expressed ankyrin factor, is essential for the vascular integrity during embryogenesis -
    [伍素瑩] 期刊論文 2009-06 A three-dimensional pharmacophore model for dipeptidyl peptidase IV inhibitiors [Erratum: European Journal of Medicinal Chemistry. 2008 Aug;43(8):1603-1611.] -
    [伍素瑩] 期刊論文 2008-08 A three-dimensional pharmacophore model for dipeptidyl peptidase IV inhibitors -
    [徐祖安] 期刊論文 2008-05 Bioassay-guided purification and identification of PPARa/gamma agonists from Chlorella sorokiniana -
    [陳新(2002-2015)] 期刊論文 2009-05-15 Biochemical properties and expression profile of human prolyl dipeptidase DPP9 -
    [陳新(2002-2015)] 期刊論文 2006-12 Biochemical properties of recombinant prolyl dipeptidases DPP-IV and DPP8 -
    [陳新(2002-2015)] 期刊論文 2009-07-15 Biochemistry, pharmacokinetics, and toxicology of a potent and selective DPP8/9 inhibitor -
    [陳新(2002-2015)] 期刊論文 2006-04 Chromatin-binding in vivo of the erythroid kruppel-like factor, EKLF, in the murine globin loci -
    [陳新(2002-2015)] 期刊論文 2011-06 Cleavage-site specificity of prolyl endopeptidase FAP investigated with a full-length protein substrate -
    [陳新(2002-2015)] 會議論文/會議摘要 2008-04-06 COMP 266-Structure, function and inhibitors of prolyl dipeptidase DPP8 -
    [陳新(2002-2015)] 期刊論文 2003-01 Congenital dyserythropoietic anemia type II: exclusion of seven candidate genes -
    [陳新(2002-2015)] 期刊論文 2013-08 Derlin2 protein facilitates HRD1-mediated retro-translocation of sonic hedgehog at the endoplasmic reticulum -
    [謝興邦] 會議論文/會議摘要 2005-03 Design, synthesis and sar of indole-based PPAR agonists -
    [謝興邦] 期刊論文 2009-04-23 Design and structural analysis of novel pharmacophores for potent and selective peroxisome proliferator-activated receptor gamma agonists -
    [謝興邦] 會議論文/會議摘要 2005-03 Design and structure-activity relationships of novel indole-based PPAR agonists as antidiabetic agents -
    [陳新(2002-2015)] 期刊論文 2007-05 Dipeptidyl peptidase 8/9-like activity in human leukocytes -
    [陳新(2002-2015)] 期刊論文 2010-12 Downregulation of signaling-active IGF-1 by dipeptidyl peptidase IV (DPP-IV) -
    [陳新(2002-2015)] 期刊論文 2014-06-09 EDEM2 and OS-9 are required for ER-associated degradation of non-glycosylated sonic hedgehog -
    [陳新(2002-2015)] 期刊論文 2009-06 Enzyme Activity and Immunohistochemical Localization of Dipeptidyl Peptidase 8 and 9 in Male Reproductive Tissues -
    [徐祖安] 期刊論文 2004-09-10 Evaluation of metal-conjugated compounds as inhibitors of 3CL protease of SARS-CoV -
    [陳新(2002-2015)] 期刊論文 2014-02 Fibroblast activation protein (FAP) is essential for the migration of bone marrow mesenchymal stem cells through RhoA activation -
    [蔣維棠] 期刊論文 2005-07-01 Glutamic acid analogues as potent dipeptidyl peptidase IV and 8 inhibitors -
    [林峯輝] 期刊論文 2016-10-07 Hydrogels bearing bioengineered mimetic embryonic microenvironments for tumor reversion -
    [陳新(2002-2015)] 期刊論文 2006-06-13 Identification of hydrophobic residues critical for DPP-IV dimerization -
    [謝興邦] 期刊論文 2006-02-09 Indol-1-yl acetic acids as peroxisome proliferator-activated receptor agonists: Design, synthesis, structural biology, and molecular docking studies -
    [謝興邦] 專利 2008-11-11 Indole compounds -
    [陳新(2002-2015)] 期刊論文 2005-07-01 Inhibition of dipeptidyl-peptidase IV catalyzed peptide truncation by vildagliptin ((2S)-{[3-hydroxyadamantan-1-yl) amino]acetyl}-pyrrolidine-2-carbonitrile) -
    [陳新(2002-2015)] 期刊論文 2008-07-15 Inhibitors of dipeptidyl peptidase 8 and dipeptidyl peptidase 9. Part 1: Identification of dipeptide derived leads -
    [陳新(2002-2015)] 期刊論文 2008-07-15 Inhibitors of dipeptidyl peptidase 8 and dipeptidyl peptidase 9. Part 2: Isoindoline containing inhibitors -
    [陳新(2002-2015)] 期刊論文 2006-12-15 Investigation of the dimer interface and substrate specificity of prolyl dipeptidase DPP8 -
    [陳新(2002-2015)] 期刊論文 2007-11-15 Irreversible inhibition of dipeptidyl peptidase 8 by dipeptide-derived diaryl phosphonates -
    [謝興邦] 會議論文/會議摘要 2006-09 MEDI 416-3- 2-((2S)-2-Cyano-pyrrolidin-1-yl)-2-oxo-ethylamino -3-methyl-butyr amide analogs as DPP-IV inhibitors for the treatment of type-II diabetes -
    [謝興邦] 期刊論文 2005-12-29 Novel indole-based peroxisome proliferator-activated receptor agonists: Design, SAR, structural biology, and biological activities -
    [陳新(2002-2015)] 期刊論文 2005-02-01 Novel isoindoline compounds for potent and selective inhibition of prolyl dipeptidase DPP8 -
    [蔣維棠] 期刊論文 2009-03-15 Novel trans-2-aryl-cyclopropylamine analogues as potent and selective dipeptidyl peptidase IV inhibitors -
    [陳新(2002-2015)] 期刊論文 2004-12-10 One site mutation disrupts dimer formation in human DPP-IV proteins -
    [陳新(2002-2015)] 期刊論文 2005-08-02 Papain-like protease 2 (PLP2) from severe acute respiratory syndrome coronavirus (SARS-CoV): Expression, purification, characterization, and inhibition -
    [陳新(2002-2015)] 期刊論文 2016-03 Probing for improved selectivity with dipeptide-derived inhibitors of dipeptidyl peptidases 8 and 9: The impact of P1-variation -
    [陳新(2002-2015)] 期刊論文 2011-03 Processing and turnover of the Hedgehog protein in the endoplasmic reticulum -
    [陳新(2002-2015)] 期刊論文 2011-09 Proline in transmembrane domain of type II protein DPP-IV governs Its translocation behavior through endoplasmic reticulum -
    [陳新(2002-2015)] 期刊論文 2008-05-01 Purification and characterization of a dipeptidyl peptidase 9-like enzyme from bovine testes -
    [陳新(2002-2015)] 期刊論文 2004-05 Purification and characterization of human prolyl dipeptidase DPPS in Sf9 insect cells -
    [蔣維棠] 專利 2010-03-30 Pyrrolidine compounds -
    [趙宇生(2002-2013)] 專利 2009-01-22 Pyrrolidine compounds -
    [蔣維棠] 專利 2008-07-01 Pyrrolidine compounds -
    [蔣維棠] 專利 2012-01-17 Pyrrolidine compounds -
    [陳新(2002-2015)] 專利 2011-12-06 Pyrrolidine compounds -
    [蔣維棠] 期刊論文 2009-04-01 Rational design and synthesis of potent and long-lasting glutamic acid-based dipeptidyl peptidase IV inhibitors -
    [陳新(2002-2015)] 期刊論文 2011-11-04 Role of a propeller loop in the quaternary structure and enzymatic activity of prolyl dipeptidases DPP-IV and DPP9 -
    [陳新(2002-2015)] 期刊論文 2014-02 Role of HERP and a HERP-related protein in HRD1-dependent protein degradation at the endoplasmic reticulum -
    [趙宇生(2002-2013)] 期刊論文 2010-10 Structural basis for the improved potency of peroxisome proliferator-activated receptor (PPAR) agonists -
    [謝興邦] 期刊論文 2006-10-19 Structural basis for the structure-activity relationships of peroxisome proliferator-activated receptor agonists -
    [陳新(2002-2015)] 期刊論文 2011-08 Structure-activity relationship studies on isoindoline inhibitors of dipeptidyl peptidases 8 and 9 (DPP8, DPP9): Is DPP8-selectivity an attainable goal? -
    [伍素瑩] 期刊論文 2006-05-04 Structure-based drug design of a novel family of PPAR gamma partial agonists: Virtual screening, X-ray crystallography, and in vitro/in vivo biological activities -
    [趙宇生(2002-2013)] 期刊論文 2010-08 Substituted 4-carboxymethylpyroglutamic acid diamides as potent and selective inhibitors of fibroblast activation protein -
    [蔣維棠] 期刊論文 2006-06-15 Substituted pyrrolidine-2,4-dicarboxylic acid amides as potent dipeptidyl peptidase IV inhibitors -
    [李岳倫] 期刊論文 2019-05 TDP-43 induces mitochondrial damage and activates the mitochondrial unfolded protein response -
    [陳新(2002-2015)] 期刊論文 2010-09 The dimeric transmembrane domain of prolyl dipeptidase DPP-IV contributes to its quaternary structure and enzymatic activities -
    [陳新(2002-2015)] 期刊論文 2009 Thiopurine analogue inhibitors of severe acute respiratory syndrome-coronavirus papain-like protease, a deubiquitinating and deISGylating enzyme -
    [陳新(2002-2015)] 期刊論文 2008-04-15 Thiopurine analogues inhibit papain-like protease of severe acute respiratory syndrome coronavirus -
    [蔣維棠] 專利 2008-07-21 吡咯啉啶化合物 -
    [陳新(2002-2015)] 專利 2013-02-11 吡咯啶化合物 -
    [趙宇生(2002-2013)] 專利 2011-02-11 吡咯烷化合物 -
    [蔣維棠] 專利 2010-10-06 吡咯烷化合物 -
    [謝興邦] 專利 2008-12-11 吲哚化合物 -
    [謝興邦] 專利 2010-12-01 吲哚化合物 -

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