鄰近類別 會議論文/會議摘要 [33/51] 專利 [0/63] 類別統計 近3年內發表的文件:13(8.84%) 含全文筆數:147(100.00%) 文件下載次數統計 下載大於0次:147(100.00%) 下載大於100次:140(95.24%) 檔案下載總次數:88027(82.28%) 最後更新時間: 2025-04-28 23:12 上傳排行 資料載入中..... 下載排行 資料載入中..... 最近上傳 KIF2C promotes paclitaxel resistanc... Identification and biological evalu... Novel naphthyridones targeting pann... Advancing precision therapy for col... Aldehyde dehydrogenases as drug tar... Discovery of novel TANK-Binding Kin... DBPR116, a prodrug of BPRMU191, in ... Discovery of dual MER/AXL kinase in... Macrophage-mediated controlled rele... Targeting cathepsin S promotes acti...

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顯示項目1-25 / 147. (共6頁) 1 2 3 4 5 6 > >> 每頁顯示[10|25|50]項目

日期	題名	關聯
2025-03-25	KIF2C promotes paclitaxel resistance by depolymerizing polyglutamylated microtubules	Developmental Cell. 2025 Mar 25;Article in Press.
2025-03-24	Identification and biological evaluation of a novel CLK4 inhibitor targeting alternative splicing in pancreatic cancer using structure-based virtual screening	Advanced Science. 2025 Mar 24;Article in Press.
2025-01	Aldehyde dehydrogenases as drug targets for cancer: SAR and structural biology aspects for inhibitor design	Bioorganic Chemistry. 2025 Jan;154:Article number 108019.
2025-01	Advancing precision therapy for colorectal cancer: Developing clinical indications for multi-target kinase inhibitor BPR1J481 using patient-derived xenograft models	Pharmacological Research. 2025 Jan;211:Article number 107556.
2024-12-30	Novel naphthyridones targeting pannexin 1 for colitis management	Advanced Science. 2024 Dec 30;Article in Press.
2024-12	Discovery of novel TANK-Binding Kinase 1 (TBK1) inhibitor against pancreatic ductal adenocarcinoma	International Journal of Biological Macromolecules. 2024 Dec;283(Part 1):Article number 137296.
2024-11	DBPR116, a prodrug of BPRMU191, in combination with naltrexone as a safer opioid analgesic than morphine via peripheral administration	Journal of Medicinal Chemistry. 2024 Nov 14;67(21):19777-19790.
2024-06-24	Macrophage-mediated controlled release of cysteine protease inhibitor from PLGA-PEG/hydroxyapatite microspheres for targeting cathepsin S in Alzheimer's disease	European Polymer Journal. 2024 Jun 24;214:Article number 113151.
2024-06-24	Discovery of dual MER/AXL kinase inhibitors as bifunctional small molecules for inhibiting tumor growth and enhancing tumor immune microenvironment	Journal of Medicinal Chemistry. 2024 Jun 24;Article in Press.
2024-05-09	Targeting cathepsin S promotes activation of OLF1-BDNF/TrkB axis to enhance cognitive function	Journal of Biomedical Science. 2024 May 09;31:Article number 46.
2023-11-03	Influence of ring strain on the formation of rearrangement vs cyclization isotwistane products in the acyl radical reaction of bicyclo[2.2.2]octanone	Organic Letters. 2023 Nov 3;25(43):7757-7762.
2023-10-05	A dual nociceptin and mu opioid receptor agonist exhibited robust antinociceptive effect with decreased side effects	European Journal of Medicinal Chemistry. 2023 Oct 05;258:Article number 115608.
2023-02-07	Development of furanopyrimidine-based orally active third-generation EGFR inhibitors for the treatment of non-small cell lung cancer	Journal of Medicinal Chemistry. 2023 Feb 7;66(4):2566-2588.
2022-09-12	A critical overview of current progress for COVID-19: Development of vaccines, antiviral drugs, and therapeutic antibodies	Journal of Biomedical Science. 2022 Sep 12;29:Article number 68.
2022-08-09	Recent advances in total synthesis of natural products by masked ortho-benzoquinones	Journal of the Chinese Chemical Society. 2022 Aug 09;69(8):1210-1222.
2022-05-09	Natural product myricetin is a pan-KDM4 inhibitor which with poly lactic-co-glycolic acid formulation effectively targets castration-resistant prostate cancer	Journal of Biomedical Science. 2022 May 9;29:Article number 29.
2022-04-06	Identification of entry inhibitors against delta and omicron variants of SARS-CoV-2	International Journal of Molecular Sciences. 2022 Apr 6;23(7):Article number 4050.
2022-01-21	Novel FLT3/AURK multikinase inhibitor is efficacious against sorafenib-refractory and sorafenib-resistant hepatocellular carcinoma	Journal of Biomedical Science. 2022 Jan 21;29:Article number 5.
2021-11-15	Design and synthesis of novel orally selective and type II pan-TRK inhibitors to overcome mutations by property-driven optimization	European Journal of Medicinal Chemistry. 2021 Nov 15;224:Article number 113673.
2021-10-14	Discovery of BPR1R024, an orally active and selective CSF1R inhibitor that exhibits antitumor and immunomodulatory activity in a murine colon tumor model	Journal of Medicinal Chemistry. 2021 Oct 14;64(19):14477-14497.
2021-07-16	Colloidal assemblies composed of polymeric micellar/emulsified systems integrate cancer therapy combining a tumor-associated antigen vaccine and chemotherapeutic regimens	Nanomaterials. 2021 Jul 16;11(7):Article number 1844.
2021-04-16	Development of a robust scale-up synthetic route for BPR1K871: A clinical candidate for the treatment of acute myeloid leukemia and solid tumors	Organic Process Research and Development. 2021 Apr 16;25(4):817-830.
2021-04-13	Chlorinated briarane diterpenoids from octocoral Briareum stechei (Kükenthal, 1908)	Tetrahedron Letters. 2021 Apr 13;69:Article number 152976.
2021-02-22	Mimicking H3 substrate arginine in the design of G9a lysine methyltransferase inhibitors for cancer therapy: A computational study for structure-based drug design	ACS Omega. 2021 Feb 22;6(9):6100-6111.
2021-01-31	Briarenols W-Z: Chlorine-containing polyoxygenated briaranes from octocoral briareum stechei (Kükenthal, 1908)	Marine Drugs. 2021 Jan 31;19(2):Article number 77.

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