邻近类别 會議論文/會議摘要 [30/48] 專利 [0/42] 类别统计 近3年内发表的文件:12(8.51%) 含全文笔数:141(100.00%) 文件下载次数统计 下载大于0次:141(100.00%) 下载大于100次:138(97.87%) 全文下载总次数:83978(82.42%) 最后更新时间: 2024-12-01 00:40 上传排行 数据加载中..... 下载排行 数据加载中..... 最近上传 DBPR116, a prodrug of BPRMU191, in ... Discovery of dual MER/AXL kinase in... Macrophage-mediated controlled rele... Targeting cathepsin S promotes acti... Influence of ring strain on the for... A dual nociceptin and mu opioid rec... Development of furanopyrimidine-bas... A critical overview of current prog... Recent advances in total synthesis ... Natural product myricetin is a pan-...

跳至: (选择年份) 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1997 1996 1995 1994 1993 1992 1991 1990 1985 1980 1975 1970 1960 1950 (选择月份) January February March April May June July August September October November December 或输入年份:

由新到旧排序 由最旧的开始

显示项目76-100 / 141. (共6页) << < 1 2 3 4 5 6 > >> 每页显示[10|25|50]项目

日期	题名	關聯
2010-09	Cancer cells acquire mitotic drug resistance properties through beta i-tubulin mutations and alterations in the expression of beta-tubulin isotypes	PLoS ONE. 2010 Sep;5(9):Article number e12564.
2010-07	Antiangiogenic Activities and Cisplatin-combined Antitumor Activities of BPR0L075	Anticancer Research. 2010 Jul;30(7):2813-2822.
2010-06-15	Fast-forwarding hit to lead: Aurora and epidermal growth factor receptor kinase inhibitor lead identification	Journal of Medicinal Chemistry. 2010 Jun 15;53(13):4980-4988.
2010-06	Design and synthesis of alpha-ketoamides as cathepsin S inhibitors with potential applications against tumor invasion and angiogenesis	Journal of Medicinal Chemistry. 2010 Jun;53(11):4545-4549.
2010-03-11	5-Amino-2-Aroylquinolines as Highly Potent Tubulin Polymerization Inhibitors	Journal of Medicinal Chemistry. 2010 Mar 11;53(5):2309-2313.
2010-02-25	Anti-influenza drug discovery: structure-activity relationship and mechanistic insight into novel angelicin derivatives	Journal of Medicinal Chemistry. 2010 Feb 25;53(4):1519-1533.
2010-02-23	Pyrazole compound BPR1P0034 with potent and selective anti-influenza virus activity	Journal of Biomedical Science. 2010 Feb 23;17:Article number 13.
2010-02-01	Identification, SAR studies, and X-ray Co-crystallographic analysis of a novel furanopyrimidine aurora kinase a inhibitor	ChemMedChem. 2010 Feb 1;5(2):255-267.
2010-02	Comparative molecular field analysis of anti-tubulin agents with indole ring binding at the colchicine binding site	Journal of Theoretical and Computational Chemistry. 2010 Feb;9(1):279-291.
2010-01	BPR2-D2 targeting viral ribonucleoprotein complex-associated function inhibits oseltamivir-resistant influenza viruses	Journal of Antimicrobial Chemotherapy. 2010 Jan;65(1):63-71.
2009-08-13	Synthesis and evaluation of 3-aroylindoles as anticancer agents: Metabolite approach	Journal of Medicinal Chemistry. 2009 Aug 13;52(15):4941-4945.
2009-07-23	Generation of ligand-based pharmacophore model and virtual screening for identification of novel tubulin inhibitors with potent anticancer activity	Journal of Medicinal Chemistry. 2009 Jul 23;52(14):4221-4233.
2009-07-03	Survivin counteracts the therapeutic effect of microtubule de-stabilizers by stabilizing tubulin polymers	Molecular Cancer. 2009 Jul 3;8:Article number 43.
2009-04-24	Bortezomib overcomes tumor necrosis factor-related apoptosis-inducing ligand resistance in hepatocellular carcinoma cells in part through the inhibition of the phosphatidylinositol 3-kinase/Akt pathway	Journal of Biological Chemistry. 2009 Apr 24;284(17):11121-11133.
2009-04-23	Design and structural analysis of novel pharmacophores for potent and selective peroxisome proliferator-activated receptor gamma agonists	Journal of Medicinal Chemistry. 2009 Apr 23;52(8):2618-2622.
2009-04-17	Synthesis and structure-activity relationships of 1-benzyl-4,5,6-trimethoxyindoles as a novel class of potent antimitotic agents	ChemMedChem. 2009 Apr 17;4(4):588-593.
2009-04	Aurora kinase inhibitors in preclinical and clinical testing	Expert Opinion on Investigational Drugs. 2009 Apr;18(4):379-398.
2009-03	Advances in Aurora kinase inhibitor patents	Expert Opinion on Therapeutic Patents. 2009 Mar;19(3):321-356.
2009-02-26	Structure-based drug design of novel aurora kinase a inhibitors: Structural basis for potency and specificity	Journal of Medicinal Chemistry. 2009 Feb 26;52(4):1050-1062.
2009-02	Aurintricarboxylic acid inhibits influenza virus neuraminidase	Antiviral Research. 2009 Feb;81(2):123-131.
2008-12-25	Synthesis and structure-activity relationships of 2-amino-1-aroylnaphthalene and 2-hydroxy-1-aroylnaphthalenes as potent antitubulin agents	Journal of Medicinal Chemistry. 2008 Dec 25;51(24):8163-8167.
2008-07-24	Discovery of 4-amino and 4-hydroxy-1-aroylindoles as potent tubulin polymerization inhibitors	Journal of Medicinal Chemistry. 2008 Jul;51(14):4351-4355.
2008-07	Anti-HSV activity of digitoxin and its possible mechanisms	Antiviral Research. 2008 Jul;79(1):62-70.
2008-06-01	A cell-based high-throughput screen for epidermal growth factor receptor pathway inhibitors	Analytical Biochemistry. 2008 Jun;377(1):89-94.
2008-05	Bioassay-guided purification and identification of PPARa/gamma agonists from Chlorella sorokiniana	Phytotherapy Research. 2008 May;22(5):605-613.

显示项目76-100 / 141. (共6页) << < 1 2 3 4 5 6 > >> 每页显示[10|25|50]项目