| 2020-03-01 |
A selective Aurora-A 5'-UTR siRNA inhibits tumor growth and metastasis |
Cancer Letters. 2020 Mar 1;472:97-107. |
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| 2020-01 |
Identification of novel quinoline inhibitor for EHMT2/G9a through virtual screening |
Biochimie. 2020 Jan;168:220-230. |
|
| 2019-12 |
Lysosomal cysteine protease cathepsin S is involved in cancer cell motility by regulating store-operated Ca(2+) entry |
Biochimica et Biophysica Acta. Molecular Cell Research. 2019 Dec;1866(12):Article number 118517. |
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| 2019-11-27 |
Discovery of a furanopyrimidine-based epidermal growth factor receptor inhibitor (DBPR112) as a clinical candidate for the treatment of non-small cell lung cancer |
Journal of Medicinal Chemistry. 2019 Nov 27;62(22):10108-10123. |
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| 2019-10-08 |
Identification of two novel small compounds that inhibit liver cancer formation in zebrafish and analysis of their conjugation to nanodiamonds to further reduce toxicity |
Advanced Therapeutics. 2019 Oct 8;2(12):Article number 1900105. |
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| 2019-07-03 |
Delineating the active site architecture of G9a lysine methyltransferase through substrate and inhibitor binding mode analysis: A molecular dynamics study |
Journal of Biomolecular Structure and Dynamics. 2019 Jul 3;37(10):2581-2592. |
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| 2019-07 |
Dual Kit/Aur inhibitors as chemosensitizing agents for the treatment of melanoma: Design, synthesis, docking studies and functional investigation |
Scientific Reports. 2019 Jul;9:Article number 9943. |
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| 2019-05-29 |
Insights for the design of protein lysine methyltransferase G9a inhibitors |
Future Medicinal Chemistry. 2019 May 29;11(9):993-1014. |
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| 2018-11 |
Biomimetic Syntheses of (±)‐Isopalhinine A, (±)‐Palhinine A, and (±)‐Palhinine D |
Angewandte Chemie. 2018 Nov;57(47):15572-15576. |
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| 2018-05-10 |
Design and synthesis of BPR1K653 derivatives targeting the back pocket of Aurora kinases for selective isoform inhibition |
European Journal of Medicinal Chemistry. 2018 May 10;151:533-545. |
|
| 2018-04-25 |
Challenging clinically unresponsive medullary thyroid cancer: Discovery and pharmacological activity of novel RET inhibitors |
European Journal of Medicinal Chemistry. 2018 Apr 25;150:491-505. |
|
| 2017-08-11 |
Targeting P-glycoprotein: Investigation of piperine analogs for overcoming drug resistance in cancer |
Scientific Reports. 2017 Aug 11;7:Article number 7972. |
|
| 2017-07 |
Drug repurposing for chronic myeloid leukemia: In silico and in vitro investigation of DrugBank database for allosteric Bcr-Abl inhibitors |
Journal of Biomolecular Structure and Dynamics. 2017 Jun;35(8):1833-1848. |
|
| 2016-12 |
Discovery of BPR1K871, a quinazoline based, multi-kinase inhibitor for the treatment of AML and solid tumors: Rational design, synthesis, in vitro and in vivo evaluation |
Oncotarget. 2016 Dec;7(52):86239-86256. |
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| 2016-11-29 |
Discovery of novel inhibitors of Aurora kinases with indazole scaffold: In silico fragment-based and knowledge-based drug design |
European Journal of Medicinal Chemistry. 2016 Nov 29;124:186-199. |
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| 2016-07 |
Therapeutic polymeric nanoparticles and the methods of making and using thereof: A patent evaluation of WO2015036792 |
Expert Opinion on Therapeutic Patents. 2016 Jul;26(7):751-755. |
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| 2016-03 |
Disruption of protein-protein interactions: Hot spot detection, structure-based virtual screening and in vitro testing for the anti-cancer drug target survivin |
RSC Advances. 2016 Mar;6(38):31947-31959. |
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| 2015-06-29 |
Homology modeling of DFG-in FMS-like tyrosine kinase 3 (FLT3) and structure-based virtual screening for inhibitor identification |
Scientific Reports. 2015 Jun 29;5:Article number 11702. |
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| 2015-02 |
Function-oriented development of CXCR4 antagonists as selective human immunodeficiency virus (HIV)-1 entry inhibitors |
Journal of Medicinal Chemistry. 2015 Feb;58(3):1452-1465. |
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| 2015-01 |
Identification of ligand efficient, fragment-like hits from an HTS library: Structure-based virtual screening and docking investigations of 2H- and 3H-pyrazolo tautomers for Aurora kinase A selectivity |
Journal of Computer-Aided Molecular Design. 2015 Jan;29(1):89-100. |
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| 2014-12 |
BPR-3P0128 inhibits RNA-dependent RNA polymerase elongation and VPg uridylylation activities of Enterovirus 71 |
Antiviral Research. 2014 Dec;112:18-25. |
|
| 2014-10 |
Small-molecule EGFR tyrosine kinase inhibitors for the treatment of cancer |
Expert Opinion on Investigational Drugs. 2014 Oct;23(10):1333-1348. |
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| 2014-08 |
CDKN1A-mediated responsiveness of MLL-AF4-positive acute lymphoblastic leukemia to Aurora kinase-A inhibitors |
International Journal of Cancer. 2014 Aug;135(3):751-762. |
|
| 2014-08 |
Ligand efficiency based approach for efficient virtual screening of compound libraries |
European Journal of Medicinal Chemistry. 2014 Aug;83:226-235. |
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| 2014-07 |
Anaplastic lymphoma kinase (ALK) inhibitors: A review of design and discovery |
MedChemComm. 2014 Jul;5(9):1266-1279. |
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