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近3年內發表的文件:13(8.84%)
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KIF2C promotes paclitaxel resistanc...
Identification and biological evalu...
Novel naphthyridones targeting pann...
Advancing precision therapy for col...
Aldehyde dehydrogenases as drug tar...
Discovery of novel TANK-Binding Kin...
DBPR116, a prodrug of BPRMU191, in ...
Discovery of dual MER/AXL kinase in...
Macrophage-mediated controlled rele...
Targeting cathepsin S promotes acti...
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2025-03-25
KIF2C promotes paclitaxel resistance by depolymerizing polyglutamylated microtubules
Developmental Cell. 2025 Mar 25;Article in Press.
2025-03-24
Identification and biological evaluation of a novel CLK4 inhibitor targeting alternative splicing in pancreatic cancer using structure-based virtual screening
Advanced Science. 2025 Mar 24;Article in Press.
2025-01
Aldehyde dehydrogenases as drug targets for cancer: SAR and structural biology aspects for inhibitor design
Bioorganic Chemistry. 2025 Jan;154:Article number 108019.
2025-01
Advancing precision therapy for colorectal cancer: Developing clinical indications for multi-target kinase inhibitor BPR1J481 using patient-derived xenograft models
Pharmacological Research. 2025 Jan;211:Article number 107556.
2024-12-30
Novel naphthyridones targeting pannexin 1 for colitis management
Advanced Science. 2024 Dec 30;Article in Press.
2024-12
Discovery of novel TANK-Binding Kinase 1 (TBK1) inhibitor against pancreatic ductal adenocarcinoma
International Journal of Biological Macromolecules. 2024 Dec;283(Part 1):Article number 137296.
2024-11
DBPR116, a prodrug of BPRMU191, in combination with naltrexone as a safer opioid analgesic than morphine via peripheral administration
Journal of Medicinal Chemistry. 2024 Nov 14;67(21):19777-19790.
2024-06-24
Macrophage-mediated controlled release of cysteine protease inhibitor from PLGA-PEG/hydroxyapatite microspheres for targeting cathepsin S in Alzheimer's disease
European Polymer Journal. 2024 Jun 24;214:Article number 113151.
2024-06-24
Discovery of dual MER/AXL kinase inhibitors as bifunctional small molecules for inhibiting tumor growth and enhancing tumor immune microenvironment
Journal of Medicinal Chemistry. 2024 Jun 24;Article in Press.
2024-05-09
Targeting cathepsin S promotes activation of OLF1-BDNF/TrkB axis to enhance cognitive function
Journal of Biomedical Science. 2024 May 09;31:Article number 46.
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