國家衛生研究院 NHRI:作者相關文件

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"Chern, JH"的相關文件

類別	日期	題名	關聯
[陳志豪] 期刊論文	2002-04-11	Design, synthesis, and structure-activity relationship of pyridyl imidazolidinones: A novel class of potent and selective human enterovirus 71 inhibitors	-
[夏克山] 期刊論文	2004-03-08	Synthesis and in vitro cytotoxicity of 5-substituted 2-cyanoimino-4-imidazodinone and 2-cyanoimino-4-pyrimidinone derivatives	-
[徐祖安] 期刊論文	2004-05-17	Design, synthesis, and structure-activity relationships of pyrazolo[3,4-d]pyrimidinies: a novel class of potent enterovirus inhibitors	-
[夏克山] 專利	2004-06-01	咪唑啉酮化合物	-
[趙宇生(2002-2013)] 期刊論文	2004-09	Mutation in enterovirus 71 capsid protein VP1 confers resistance to the inhibitory effects of pyridyl imidazolidinone	-
[夏克山] 期刊論文	2004-10-18	Synthesis and antienteroviral activity of a series of novel, oxime ether-containing pyridyl imidazolidinones	-
[陳志豪] 專利	2004-11-09	Anti-enterovirus compounds	-
[陳志豪] 期刊論文	2005-05-19	Design, synthesis, and antipicornavirus activity of 1-[5-(4-arylphenoxy)alkyl]-3-pyridin-4-ylimidazolidin-2-one derivatives	-
[陳志豪] 期刊論文	2005-10-01	Synthesis and antipicornavirus activity of (R)- and (S)-1-[5-(4 '-chlorobiphenyl-4-yloxy)-3-methylpentyl]-3-pyridin-4-yl-imidazolidin-2-one	-
[陳志豪] 專利	2006-08-01	抗腸病毒化合物	-
[陳志豪] 專利	2006-10-31	Imidazolidinone compounds	-
[陳志豪] 專利	2007-06-01	咪唑啉酮化合物	-
[陳志豪] 專利	2007-08-21	Imidazolidinone compounds	-
[陳志豪] 期刊論文	2008-05	Antiviral activity of pyridyl imidazolidinones against enterovirus 71 variants	-
[李秀珠] 期刊論文	2008-10-15	Analogues of 2-phenyl-ethenesulfonic acid phenyl ester have dual functions of inhibiting expression of inducible nitric oxide synthase and activating peroxisome proliferator-activated receptor gamma	-
[陳志豪] 專利	2009-03-10	Imidazolidinone compounds	-
[陳志豪] 期刊論文	2009-04-01	Design, synthesis, and anti-HCV activity of thiourea compounds	-
[徐祖安] 期刊論文	2009-07	Novel antiviral agent DTriP-22 targets RNA-dependent RNA polymerase of enterovirus 71	-
[陳志豪] 期刊論文	2009-08-01	Design and synthesis of indole, 2,3-dihydro-indole, and 3,4-dihydro-2H-quinoline-1-carbothioic acid amide derivatives as novel HCV inhibitors	-
[陳志豪] 期刊論文	2009-11-01	Design and efficient synthesis of novel arylthiourea derivatives as potent hepatitis C virus inhibitors	-
[陳志豪] 專利	2010-05-11	咪唑啉酮化合物	-
[陳志豪] 專利	2010-08-21	硫尿化合物及抑制C型肝炎病毒感染之方法	-
[趙宇生(2002-2013)] 期刊論文	2010-09-01	Synthesis, activity, and pharmacokinetic properties of a series of conformationally-restricted thiourea analogs as novel hepatitis C virus inhibitors	-
[陳志豪] 期刊論文	2010-10	Modulation of microglial immune responses by a novel thiourea derivative	-
[趙宇生(2002-2013)] 期刊論文	2011-01	Novel dengue virus-specific NS2B/NS3 protease inhibitor, BP2109, discovered by a high-throughput screening assay	-
[陳炯東] 期刊論文	2011-01	BPR0C261 is a novel orally active antitumor agent with antimitotic and anti-angiogenic activities	-
[陳志豪] 專利	2011-03-01	Thiourea derivatives	-
[陳志豪] 期刊論文	2011-04	Antitumor effect of BPR-DC-2, a novel synthetic cyclic cyanoguanidine derivative, involving the inhibition of MDR-1 expression and down-regulation of p-AKT and PARP-1 in lung cancer	-
[徐祖安] 期刊論文	2011-04	Isatin-beta-thiosemicarbazones as potent herpes simplex virus inhibitors	-
[陳志豪] 專利	2011-05-10	Imidazolidinone and imidazolidinethione derivatives	-
[徐祖安] 專利	2011-07-26	Hepatitis C virus inhibitors	-
[岳嶽] 期刊論文	2012-01	Resistance analysis and characterization of a thiazole analogue, BP008, as a potent hepatitis C virus NS5A inhibitor	-
[陳志豪] 專利	2012-03-01	C型肝炎病毒抑制劑	-
[陳志豪] 專利	2012-04-11	咪唑啉酮及咪唑啉硫酮衍生物	-
[謝奉勳] 專利	2012-06-12	Treatment of neurodegenerative disorders with thiourea compounds	-
[岳嶽] 期刊論文	2013-02	Resistance studies of a di-thiazol analogue, DBPR110, as a potential hepatitis C virus NS5A inhibitor in replicon systems	-
[陳志豪] 專利	2013-04-09	Proline derivatives	-
[岳嶽] 期刊論文	2014-01	A novel dengue virus inhibitor, BP13944, discovered by high-throughput screening with dengue virus replicon cells selects for resistance in the viral NS2B/NS3 protease	-
[陳志豪] 專利	2014-03-11	脯胺酸衍生物	-
[謝奉勳] 專利	2014-09-01	治療阿茲海默症或帕金森氏症之醫藥組成物	-
[陳志豪] 專利	2015-07-29	脯氨酸衍生物	-
[葉燈光] 期刊論文	2016-07	In vitro and in vivo studies of a potent capsid-binding inhibitor of enterovirus 71	-
[陳志豪] 期刊論文	2017-01	A potent, selective, and orally bioavailable HCV NS5A inhibitor for treatment of Hepatitis C Virus: (S)-1-((R)-2-(Cyclopropanecarboxamido)-2-phenylacetyl)-N-(4-phenylthiazo l-2-yl)pyrrolidine-2-carboxamide	-
[岳嶽] 期刊論文	2017-06	Mutagenesis of dengue virus protein NS2A revealed a novel domain responsible for virus-induced cytopathic effect and interactions between NS2A and NS2B transmembrane segments	-
[謝奉勳] 期刊論文	2017-12	Stimulatory actions of a novel thiourea derivative on large-conductance, calcium-activated potassium channels	-
[岳嶽] 期刊論文	2018-09	Development of robust genotype 1a hepatitis C replicons harboring adaptive mutations for facilitating the antiviral drug discovery and study of virus replication	-
[陳志豪] 期刊論文	2019-04-01	A novel, potent, and orally bioavailable thiazole HCV NS5A inhibitor for the treatment of hepatitis C virus	-
[岳嶽] 期刊論文	2019-12	A novel flavivirus entry inhibitor, BP34610, discovered through high-throughput screening with dengue reporter viruses	-
[陳志豪] 期刊論文	2020-12	Rosmarinic acid exhibits broad anti-enterovirus A71 activity by inhibiting the interaction between the five-fold axis of capsid VP1 and cognate sulfated receptors	-
[陳志豪] 期刊論文	2022-08	Rosmarinic acid interferes with influenza virus A entry and replication by decreasing GSK3beta and phosphorylated AKT expression levels	-

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