2021-12-14 |
A novel NRF2/ARE inhibitor gossypol induces cytotoxicity and sensitizes chemotherapy responses in chemo-refractory cancer cells |
Journal of Food and Drug Analysis. 2021 Dec 14;29(4):638-652. |
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2021-11-16 |
Identification of prognostic biomarkers originating from the tumor stroma of betel quid-associated oral cancer tissues |
Frontiers in Oncology. 2021 Nov 16;11:Article number 769665. |
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2021-04 |
Phase I dose-escalation study of SCB01A, a microtubule inhibitor with vascular disrupting activity, in patients with advanced solid tumors |
Oncologist. 2021 Apr;26(4):e567-e579. |
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2021-03-11 |
c-MYC-directed NRF2 drives malignant progression of head and neck cancer via glucose-6-phosphate dehydrogenase and transketolase activation |
Theranostics. 2021 Mar 11;11(11):5232-5247. |
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2021-03-04 |
Targeting lysosomal cysteine protease cathepsin S reveals immunomodulatory therapeutic strategy for oxaliplatin-induced peripheral neuropathy |
Theranostics. 2021 Mar 4;11(10):4672-4687. |
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2021-01-12 |
Ephrin A4-ephrin receptor A10 signaling promotes cell migration and spheroid formation by upregulating NANOG expression in oral squamous cell carcinoma cells |
Scientific Reports. 2021 Jan 12;11:Article number 644. |
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2020-08 |
The SMAC mimetic LCL161 is a direct ABCB1/MDR1-ATPase activity modulator and BIRC5/Survivin expression down-regulator in cancer cells |
Toxicology and Applied Pharmacology. 2020 Aug;401:Article number 115080. |
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2020-07-17 |
Germline susceptibility variants impact clinical outcome and therapeutic strategies for stage III colorectal cancer[Erratum:Scientific Reports. 2019 Mar;9:Article number 3931.] |
Scientific Reports. 2020 Jul 17;10:Article number 12216. |
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2020-06-28 |
Index of cancer-associated fibroblasts is superior to the epithelial–mesenchymal transition score in prognosis prediction |
Cancers. 2020 Jun 28;12(7):Article number 1718. |
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2020-06 |
Pharmacological inhibition of cathepsin S suppresses abdominal aortic aneurysm in mice |
European Journal of Vascular and Endovascular Surgery. 2020 Jun;59(6):990-999. |
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2020-05-27 |
The tumor suppressor TGFBR3 blocks lymph node metastasis in head and neck cancer |
Cancers. 2020 May 27;12(6):Article number 1375. |
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2020-04-02 |
MiR-30a and miR-379 modulate retinoic acid pathway by targeting DNA methyltransferase 3B in oral cancer |
Journal of Biomedical Science. 2020 Apr 2;27:Article number 46. |
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2020-03-31 |
Discoidin domain receptor-1 (DDR1) is involved in angiolymphatic invasion in oral cancer |
Cancers. 2020 Mar 31;12(4):Article number 841. |
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2019-12 |
Lysosomal cysteine protease cathepsin S is involved in cancer cell motility by regulating store-operated Ca(2+) entry |
Biochimica et Biophysica Acta. Molecular Cell Research. 2019 Dec;1866(12):Article number 118517. |
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2019-08-24 |
New insights into mechanisms of cisplatin resistance: From tumor cell to microenvironment |
International Journal of Molecular Sciences. 2019 Aug 24;20(17):Article number 4136. |
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2019-07 |
Cathepsin S inhibition alleviates oxaliplatin-induced peripheral neuropathy through regulation of Ca2+homeostasis |
Cancer Research. 2019 Jul;79(13, Suppl.):Abstract number 2942. |
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2019-06-01 |
Laminin gamma2-enriched extracellular vesicles of oral squamous cell carcinoma cells enhance in vitro lymphangiogenesis via intergrin alpha3-dependent uptake by lymphatic endothelial cells |
International Journal of Cancer. 2019 Jun 1;144(11):2795-2810. |
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2019-06 |
Sequential therapy of neoadjuvant biochemotherapy with cetuximab, paclitaxel, and cisplatin followed by cetuximab-based concurrent bioradiotherapy in high-risk locally advanced oral squamous cell carcinoma: Final analysis of a phase 2 clinical trial |
Head and Neck. 2019 Jun;41(6):1703-1712. |
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2019-06 |
Validation of alcohol flushing questionnaire to identify ALDH2 status in a case-control study of head and neck cancer |
Alcoholism, Clinical and Experimental Research. 2019 Jun;43(6):1225-1233. |
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2019-04 |
Oral hygiene and the overall survival of head and neck cancer patients |
Cancer Medicine. 2019 Apr;8(4):1854-1864. |
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2019-03-20 |
TNF-alpha-induced miR-450a mediates TMEM182 expression to promote oral squamous cell carcinoma motility |
PLoS ONE. 2019 Mar 20;14(3):Article number e0213463. |
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2019-03 |
Germline susceptibility variants impact clinical outcome and therapeutic strategies for stage III colorectal cancer |
Scientific Reports. 2019 Mar;9:Article number 3931. |
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2019-02 |
The influence of prediagnosis alcohol consumption and the polymorphisms of ethanol metabolizing genes on the survival of head and neck cancer patients |
Cancer Epidemiology, Biomarkers and Prevention. 2019 Feb;28(2):248-257. |
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2019-01-15 |
1-Arylsulfonyl indoline-benzamides as a new antitubulin agents, with inhibition of histone deacetylase |
European Journal of Medicinal Chemistry. 2019 Jan 15;162:612-630. |
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2018-12 |
Ubiquitin-conjugating enzyme E2 B regulates the ubiquitination of O(6)-methylguanine-DNA methyltransferase and BCNU sensitivity in human nasopharyngeal carcinoma cells |
Biochemical Pharmacology. 2018 Dec;158:327-338. |
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2018-12 |
The clinical implication of O6 methylguanine DNA methyltransferase in rectal cancers |
Cancer Science. 2018 Dec;109(Suppl. 2):1369. |
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2018-11 |
Alpha-tubulin acetyltransferase/MEC-17 regulates cancer cell migration and invasion through epithelial-mesenchymal transition suppression and cell polarity disruption |
Scientific Reports. 2018 Nov;8:Article number 17477. |
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2018-06-15 |
2-Aroylquinoline-5,8-diones as potent anticancer agents displaying tubulin and heat shock protein 90 (HSP90) inhibition [Erratum: Organic and Biomolecular Chemistry. 2016 Jan;14(2):716-723.] |
Organic and biomolecular chemistry. 2018 Jun 15;16:4734. |
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2018-06 |
The interplay between oral microbiome, lifestyle factors, and genetic polymorphisms in the risk of oral squamous cell carcinoma |
Carcinogenesis. 2018 Jun;39(6):778-787. |
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2018-05-29 |
Homoharringtonine induced immune alteration for an efficient anti-tumor response in mouse models of non-small cell lung adenocarcinoma expressing Kras mutation |
Scientific Reports. 2018 May 29;8:Article number 8216. |
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2018-03-28 |
Novel microtubule inhibitor MPT0B098 inhibits hypoxia-induced epithelial-to-mesenchymal transition in head and neck squamous cell carcinoma |
Journal of Biomedical Science. 2018 Mar 28;25:Article number 28. |
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2018-01 |
O6BG modulates the repair activity of homologous recombination and its clinical application |
Cancer Science. 2018 Jan;109(Suppl. 1):379. |
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2017-12-15 |
Skin Delivery of Clec4a small hairpin RNA Elicited an effective antitumor response by enhancing CD8(+) immunity in vivo |
Molecular Therapy-Nucleic Acids. 2017 Dec 15;9:419-427. |
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2017-12 |
Enhanced B-Raf-mediated NRF2 gene transcription and HATs-mediated NRF2 protein acetylation contributes to ABCC1-mediated chemoresistance and glutathione-mediated survival in acquired topoisomerase II poison-resistant cancer cells |
Free Radical Biology and Medicine. 2017 Dec;113:505-518. |
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2017-10-24 |
Investigating the association between diet and risk of head and neck cancer in Taiwan |
Oncotarget. 2017 Oct 24;8(58):98865-98875. |
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2017-10 |
Epidermal growth factor-induced pyruvate dehydrogenase kinase 1 expression enhances head and neck squamous cell carcinoma metastasis via up-regulation of fibronectin |
FASEB Journal. 2017 Oct;31(10):4265-4276. |
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2017-10 |
The c.1085A>G genetic variant of CSF1R gene regulates tumor immunity by altering the proliferation, polarization, and function of macrophages |
Clinical Cancer Research. 2017 Oct;23(20):6021-6030. |
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2017-08-29 |
Investigating the association between alcohol and risk of head and neck cancer in Taiwan |
Scientific Reports. 2017 Aug 29;7:Article number 9701. |
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2017-06-20 |
Chronic treatment with cisplatin induces chemoresistance through the TIP60-mediated Fanconi anemia and homologous recombination repair pathways |
Scientific Reports. 2017 Jun 20;7:Article number 3879. |
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2017-04-21 |
Regular recreational physical activity and risk of head and neck cancer |
BMC Cancer. 2017 Apr 21;17:Article number 286. |
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2017-03-28 |
Minoxidil is a potential neuroprotective drug for paclitaxel-induced peripheral neuropathy |
Scientific Reports. 2017 Mar 28;7:Article number 45366. |
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2017-01-25 |
Parathyroid hormone-like hormone is a poor prognosis marker of head and neck vancer and promotes cell growth via RUNX2 regulation |
Scientific Reports. 2017 Jan 25;7:Article number 41131. |
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2016-12-15 |
Dysregulation of RUNX2/activin-A axis upon miR-376c downregulation promotes lymph node metastasis in head and neck squamous cell carcinoma |
Cancer Research. 2016 Dec 15;76(24):7140-7150. |
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2016-10-25 |
A comprehensive analysis on the association between tobacco-free Betel Quid and risk of Head and Neck Cancer in Taiwanese men |
PLoS ONE. 2016 Oct 25;11(10):Article number e0164937. |
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2016-09 |
Up-regulation of miR-455-5p by the TGF-beta–SMAD signalling axis promotes the proliferation of oral squamous cancer cells by targeting UBE2B |
Journal of Pathology. 2016 Sep;240(1):38-49. |
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2016-08-24 |
A phase I clinical study of immunotherapy for advanced colorectal cancers using carcinoembryonic antigen-pulsed dendritic cells mixed with tetanus toxoid and subsequent IL-2 treatment |
Journal of Biomedical Science. 2016 Aug 24;23:Article number 64. |
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2016-08 |
Desferal regulates hCtr1 and transferrin receptor expression through Sp1 and exhibits synergistic cytotoxicity with platinum drugs in oxaliplatin-resistant human cervical cancer cells in vitro and in vivo |
Oncotarget. 2016 Aug;7(31):49310-49321. |
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2016-07-08 |
Cathepsin S attenuates endosomal EGFR signalling: A mechanical rationale for the combination of cathepsin S and EGFR tyrosine kinase inhibitors |
Scientific Reports. 2016 Jul 8;6:Article number 29256. |
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2016-07-01 |
MPT0B098, a microtubule inhibitor, suppresses JAK2/STAT3 signaling pathway through modulation of SOCS3 stability in oral squamous cell carcinoma |
PLoS ONE. 2016 Jul 1;11(7):Article number e0158440. |
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2016-07 |
Development of nanoliposomal irinotecan (nal-IRI, MM-398, PEP02) in the management of metastatic pancreatic cancer |
Expert Opinion on Pharmacotherapy. 2016 Jul;17(10):1413-1420. |
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