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Xanthine derivatives reveal an allo...
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2010-06-15
(2S,4S)-1-[2-(1,1-Dimethyl-3-oxo-3-pyrrolidin-1-yl-propylamino)acetyl]-4-fluoro-pyrrolidine-2-carbonitrile: A potent, selective, and orally bioavailable dipeptide-derived inhibitor of dipeptidyl peptidase IV
Bioorganic and Medicinal Chemistry Letters. 2010 Jun 15;20(12):3596-3600.
2009-10
(1,3-Diphenyl-1H-pyrazol-4-yl)-methylamine analogues as inhibitors of dipeptidyl peptidases
Journal of the Chinese Chemical Society. 2009 Oct;56(5):1048-1055.
2009-07-15
Biochemistry, pharmacokinetics, and toxicology of a potent and selective DPP8/9 inhibitor
Biochemical Pharmacology. 2009 Jul 15;78(2):203-210.
2009-06
A three-dimensional pharmacophore model for dipeptidyl peptidase IV inhibitiors [Erratum: European Journal of Medicinal Chemistry. 2008 Aug;43(8):1603-1611.]
European Journal of Medicinal Chemistry. 2009 Jun;44(6):2763-2763.
2009-04-01
Rational design and synthesis of potent and long-lasting glutamic acid-based dipeptidyl peptidase IV inhibitors
Bioorganic and Medicinal Chemistry Letters. 2009 Apr 1;19(7):1908-1912.
2009-03-15
Novel trans-2-aryl-cyclopropylamine analogues as potent and selective dipeptidyl peptidase IV inhibitors
Bioorganic and Medicinal Chemistry. 2009 Mar 15;17(6):2388-2399.
2008-08
A three-dimensional pharmacophore model for dipeptidyl peptidase IV inhibitors
European Journal of Medicinal Chemistry. 2008 Aug;43(8):1603-1611.
2007-03-01
3-[2-((2S)-2-Cyano-pyrrolidin-1-yl)-2-oxo-ethylamino]-3-methyl-butyramide analogues as selective DPP-IV inhibitors for the treatment of type-II diabetes
Bioorganic and Medicinal Chemistry Letters. 2007 Mar;17(5):1274-1279.
2006-06-15
Substituted pyrrolidine-2,4-dicarboxylic acid amides as potent dipeptidyl peptidase IV inhibitors
Bioorganic and Medicinal Chemistry Letters. 2006 Jun;16(12):3268-3272.
2006-01-12
2-[3-[2-[(2S)-2-cyano-1-pyrrolidinyl]-2-oxoethylamino]-3-methyl-1-oxobutyl]-1,2,3,4-tetrahydroisoquinoline: A potent, selective, and orally bioavailable dipeptide-derived inhibitor of dipeptidyl peptidase IV
Journal of Medicinal Chemistry. 2006 Jan;49(1):373-380.
2005-07-01
Glutamic acid analogues as potent dipeptidyl peptidase IV and 8 inhibitors
Bioorganic and Medicinal Chemistry Letters. 2005 Jul;15(13):3271-3275.
2005-04-15
Benzothiazolium compounds: Novel classes of inhibitors that suppress the nitric oxide production in RAW264.7 cells stimulated by LPS/IFN gamma
Bioorganic and Medicinal Chemistry Letters. 2005 Apr;15(8):2027-2032.
2005-02-01
Novel isoindoline compounds for potent and selective inhibition of prolyl dipeptidase DPP8
Bioorganic and Medicinal Chemistry Letters. 2005 Feb;15(3):687-691.
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