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Institute of Biotechnology and Pharmaceutical Research
Weir-Torn Jiaang
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Advancing precision therapy for col...
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Date
Title
Relation
2012-01
BPR1J-097, a novel FLT3 kinase inhibitor, exerts potent inhibitory activity against AML
British Journal of Cancer. 2012 Jan;106(3):475-481.
2011-07
Discovery and evaluation of 3-phenyl-1H-5-pyrazolylamine-based derivatives as potent, selective and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3)
Bioorganic and Medicinal Chemistry. 2011 Jul;19(14):4173-4182 .
2011-06
Current advances and therapeutic potential of agents targeting dipeptidyl peptidases-IV, -II, 8/9 and fibroblast activation protein
Current Topics In Medicinal Chemistry. 2011 Jun;(11):1447-1463.
2011-06
Cleavage-site specificity of prolyl endopeptidase FAP investigated with a full-length protein substrate
Journal of Biochemistry. 2011 Jun;149(6):685-692.
2011-02
Synthesis of 3,3-dimethylglutamic acid derivatives as DPP-IV inhibitors and evaluation of their chemical stability
Journal of the Chinese Chemical Society. 2011 Feb;58(1):108-117.
2010-09
The dimeric transmembrane domain of prolyl dipeptidase DPP-IV contributes to its quaternary structure and enzymatic activities
Protein Science. 2010 Sep;19(9):1627-1638.
2010-08
Substituted 4-carboxymethylpyroglutamic acid diamides as potent and selective inhibitors of fibroblast activation protein
Journal of Medicinal Chemistry. 2010 Aug;53(18):6572-6583.
2010-06-15
(2S,4S)-1-[2-(1,1-Dimethyl-3-oxo-3-pyrrolidin-1-yl-propylamino)acetyl]-4-fluoro-pyrrolidine-2-carbonitrile: A potent, selective, and orally bioavailable dipeptide-derived inhibitor of dipeptidyl peptidase IV
Bioorganic and Medicinal Chemistry Letters. 2010 Jun 15;20(12):3596-3600.
2009-10
(1,3-Diphenyl-1H-pyrazol-4-yl)-methylamine analogues as inhibitors of dipeptidyl peptidases
Journal of the Chinese Chemical Society. 2009 Oct;56(5):1048-1055.
2009-07-15
Biochemistry, pharmacokinetics, and toxicology of a potent and selective DPP8/9 inhibitor
Biochemical Pharmacology. 2009 Jul 15;78(2):203-210.
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