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Institute of Biotechnology and Pharmaceutical Research
Ming-Shiu Hung
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Decrypting orphan GPCR drug discove...
Natural fucoidans inhibit coronavir...
Modulating the affinity and signali...
Discovery and development of a nove...
Unique sulfur-aromatic interactions...
A structure-function approach ident...
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Median nerve stimulation induces an...
DUSP6 mediates T cell receptor-enga...
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Date
Title
Relation
2024-01-23
Decrypting orphan GPCR drug discovery via multitask learning
Journal of Cheminformatics. 2024 Jan 23;16:Article number 10.
2023-07-20
Natural fucoidans inhibit coronaviruses by targeting viral spike protein and host cell furin
Biochemical Pharmacology. 2023 Jul 20;215:Article number 115688.
2023-01
Modulating the affinity and signaling bias of cannabinoid receptor 1 antagonists
Bioorganic Chemistry. 2023 Jan;130:Article number 106236.
2022-02-05
Discovery and development of a novel N-(3-bromophenyl)-{[(phenylcarbamoyl)amino]methyl}-N-hydroxythiophene-2-carboximidamide indoleamine 2,3-dioxygenase inhibitor using knowledge-based drug design
European Journal of Medicinal Chemistry. 2022 Feb 5;229:Article number 114043.
2020-02-10
Unique sulfur-aromatic interactions contribute to the binding of potent imidazothiazole indoleamine 2,3-Dioxygenase inhibitors
Journal of Medicinal Chemistry. 2020 Feb 10;63(4):1642-1659.
2019-08
A structure-function approach identifies L-PGDS as a mediator responsible for glucocorticoid-induced leptin expression in adipocytes
Biochemical Pharmacology. 2019 Aug;166:203-211.
2019-01-01
Fluorine-18 isotope labeling for positron emission tomography imaging. Direct evidence for DBPR211 as a peripherally restricted CB1 inverse agonist
Bioorganic and Medicinal Chemistry. 2019 Jan 1;27(1):216-223.
2018-10-06
Median nerve stimulation induces analgesia via orexin-initiated endocannabinoid disinhibition in the periaqueductal gray
Proceedings of the National Academy of Sciences of the United States of America. 2018 Nov;115(45):E10720-E10729.
2018-08-21
DUSP6 mediates T cell receptor-engaged glycolysis and restrains TFH cell differentiation
Proceedings of the National Academy of Sciences of the United States of America. 2018 Aug 21;115(34):E8027-E8036.
2018-04
4-Bromophenylhydrazinyl benzenesulfonylphenylureas as indoleamine 2,3-dioxygenase inhibitors with in vivo target inhibition and anti-tumor efficacy
Bioorganic Chemistry. 2018 Apr;77:600-607.
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