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生技與藥物研究所
陳炯東
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Orally bioavailable and site-select...
Natural fucoidans inhibit coronavir...
Integrating ultrabright polymer dot...
Advancing precision therapy for col...
DBPR116, a prodrug of BPRMU191, in ...
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Showing items 1-10 of 161. (17 Page(s) Totally)
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2025-02-27
Orally bioavailable and site-selective covalent STING inhibitor derived from a macrocyclic marine diterpenoid
Journal of Medicinal Chemistry. 2025 Feb 27;Article in Press.
2025-02
Natural fucoidans inhibit coronaviruses by targeting viral spike protein and host cell furin[Erratum:Biochemical Pharmacology. 2023 Jul 20;215:Article number 115688.]
Biochemical Pharmacology. 2025 Feb;232:Article number 116753.
2025-01-05
Integrating ultrabright polymer dots and stereo NIR-II imager for assessing anti-angiogenic drugs in oral cancer model
Journal of Cellular and Molecular Medicine. 2025 Jan 05;29(1):Article number e70324.
2025-01
Advancing precision therapy for colorectal cancer: Developing clinical indications for multi-target kinase inhibitor BPR1J481 using patient-derived xenograft models
Pharmacological Research. 2025 Jan;211:Article number 107556.
2024-11-21
Discovery of a mu-opioid receptor modulator that in combination with morphinan antagonists induces analgesia
Cell Chemical Biology. 2024 Nov 21;31(11):1885-1898.e10.
2024-11
DBPR116, a prodrug of BPRMU191, in combination with naltrexone as a safer opioid analgesic than morphine via peripheral administration
Journal of Medicinal Chemistry. 2024 Nov 14;67(21):19777-19790.
2024-06-01
Discovery of a long half-life AURKA inhibitor to treat MYC-amplified solid tumors as a monotherapy and in combination with everolimus
Molecular Cancer Therapeutics. 2024 Jun 01;23(6):766-779.
2024-02-16
Postfermented tea extract potently alleviates glucose metabolism disorders in vitro and in vivo
ACS Food Science and Technology. 2024 Feb 16;4(2):479-490.
2023-07-20
Natural fucoidans inhibit coronaviruses by targeting viral spike protein and host cell furin
Biochemical Pharmacology. 2023 Jul 20;215:Article number 115688.
2023-02-07
Development of furanopyrimidine-based orally active third-generation EGFR inhibitors for the treatment of non-small cell lung cancer
Journal of Medicinal Chemistry. 2023 Feb 7;66(4):2566-2588.
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