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    Items for Author "Shia, KS" 

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    Showing 94 items.

    Collection Date Title Relation Bitstream
    [伍素瑩] 期刊論文 2020-02-10 Unique sulfur-aromatic interactions contribute to the binding of potent imidazothiazole indoleamine 2,3-Dioxygenase inhibitors -
    [伍素瑩] 期刊論文 2016-01 Important hydrogen bond networks in Indoleamine 2,3-Dioxygenase 1 (IDO1) inhibitor design revealed by crystal structures of imidazoleisoindole derivatives with IDO1 -
    [夏克山] 圖書 2008-03 流感抗病毒藥物介紹 -
    [夏克山] 專利 2015-02-24 Pyrazole compounds -
    [夏克山] 專利 2015-02-11 吡唑類化合物 -
    [夏克山] 專利 2014-11-19 咪唑-4-酮及咪唑-4-硫酮化合物 -
    [夏克山] 專利 2014-07-30 Pyrazole compounds -
    [夏克山] 專利 2014-04-21 咪唑-4-酮及咪唑-4-硫酮化合物 -
    [夏克山] 專利 2013-09-11 噻吩化合物及其醫藥組成物 -
    [夏克山] 專利 2013-01-15 Imidazol-4-one and imidazole-4-thione compounds -
    [夏克山] 專利 2012-07-04 噻吩化合物 -
    [夏克山] 專利 2011-10-01 硒吩化合物及其醫藥組成物 -
    [夏克山] 專利 2011-08-11 噁二唑化合物 -
    [夏克山] 專利 2011-03-21 吡唑化合物及其醫藥組成物 -
    [夏克山] 專利 2010-11-16 Thiophene compounds -
    [夏克山] 專利 2010-09-28 Selenophene compounds -
    [夏克山] 專利 2010-04-27 Oxadiazole compounds -
    [夏克山] 專利 2004-06-01 咪唑啉酮化合物 -
    [夏克山] 會議論文/會議摘要 2007-03 First total synthesis of the cis-clerodane diterpenoids solidagolactones IV and V -
    [夏克山] 會議論文/會議摘要 2001-04 Improved general synthetic approach to cis-clerodane diterpenoids: A more efficient total synthesis of (+/-)-6 beta-acetoxy-2-oxokolavenool -
    [夏克山] 期刊論文 2023-03-17 A convenient diels-alder approach toward potential polyketide-like antibiotics using alpha-activated alpha,Beta-unsaturated 4,4-dimethyl-1-tetralones as dienophiles -
    [夏克山] 期刊論文 2022-10-03 Protective effect of CXCR4 antagonist DBPR807 against ischemia-reperfusion injury in a rat and porcine model of myocardial infarction: Potential adjunctive therapy for percutaneous coronary intervention -
    [夏克山] 期刊論文 2021-07-21 Anionic diels-alder chemistry of cyclic sodium dien-1-olates delivering highly stereoselective and functionalized polycyclic adducts -
    [夏克山] 期刊論文 2021-03-30 A highly selective and potent CXCR4 antagonist for hepatocellular carcinoma treatment -
    [夏克山] 期刊論文 2021-03-02 Total synthesis of landomycins Q and R and related core structures for exploration of the cytotoxicity and antibacterial properties -
    [夏克山] 期刊論文 2020-04 Development of a cross-conjugated vinylogous [4+2] anionic annulation and application to the total synthesis of natural antibiotic (±)-ABX -
    [夏克山] 期刊論文 2020-01-16 Development of a cross-conjugated vinylogous [4+2] anionic annulation and application to the total synthesis of natural antibiotic (±)-ABX -
    [夏克山] 期刊論文 2019-01-01 Fluorine-18 isotope labeling for positron emission tomography imaging. Direct evidence for DBPR211 as a peripherally restricted CB1 inverse agonist -
    [夏克山] 期刊論文 2018-12-07 Temperature-controlled thiation of alpha-Cyano-beta-Alkynyl carbonyl derivatives for de vovo synthesis of 2-Aminothiophenes and thieno[2,3- c]isothiazoles -
    [夏克山] 期刊論文 2018-08 Auroramycin: A potent antibiotic from streptomyces roseosporus by CRISPR-Cas9 activation -
    [夏克山] 期刊論文 2018-07 Harnessing CXCR4 antagonists in stem cell mobilization, HIV infection, ischemic diseases, and oncology -
    [夏克山] 期刊論文 2018-07 Synergic effect of curcumin and its structural analogue (Monoacetylcurcumin) on anti-influenza virus infection -
    [夏克山] 期刊論文 2018-05-22 Total synthesis of tetarimycin A, (±)-Naphthacemycin A9, and (±)-Fasamycin A: structure-activity relationship studies against drug-resistant bacteria -
    [夏克山] 期刊論文 2018-02-08 Development of stem-cell-mobilizing agents targeting CXCR4 receptor for peripheral blood stem cell transplantation and beyond -
    [夏克山] 期刊論文 2016-11-18 Cobalt(II)-catalyzed aerobic oxidation of terminal-capped alkynyl alpha-cyano alkanone systems. An oxygen-mediated radical chain reaction -
    [夏克山] 期刊論文 2016-01 Synthesis of (E)-oxindolylidene acetate using tandem palladium-catalyzed Heck and alkoxycarbonylation reactions -
    [夏克山] 期刊論文 2015-08-14 Studies on antibiotics active against resistant bacteria. Total synthesis of MRSA-active tetarimycin A and its analogues -
    [夏克山] 期刊論文 2015-06-15 Synthesis and evaluation of 3-ylideneoxindole acetamides as potent anticancer agents -
    [夏克山] 期刊論文 2015-06-15 The total synthesis of retrojusticidin B, justicidin E, and helioxanthin -
    [夏克山] 期刊論文 2015-03 Stem cell mobilizers targeting chemokine receptor CXCR4: Renoprotective application in acute kidney injury -
    [夏克山] 期刊論文 2015-02 Function-oriented development of CXCR4 antagonists as selective human immunodeficiency virus (HIV)-1 entry inhibitors -
    [夏克山] 期刊論文 2014-10 Manganese(III)-catalyzed oxidative cyclization of aryl 1-cyanoalk-5-ynyl ketone systems: A convenient and general approach to cyclopenta[b]naphthalene derivatives -
    [夏克山] 期刊論文 2014-03 Double michael addition reactions of the nazarov reagent with 2-cyano-2-cycloalkenones: An alternative approach to cis-fused bicyclic systems -
    [夏克山] 期刊論文 2013-11-13 Discovery of 1-(2,4-Dichlorophenyl)-N-(piperidin-1-yl)-4-((pyrrolidine-1-sulfonamido)methyl)-5 -(5-((4-(trifluoromethyl)phenyl)ethynyl)thiophene-2-yl)-1H-pyrazole-3-carboxamide as a novel peripherally restricted cannabinoid-1 receptor antagonist with significant weight-loss efficacy in diet-induced obese mice -
    [夏克山] 期刊論文 2013-04 Palladium(0)/copper(I)-catalyzed tandem cyclization of aryl 1-cyanoalk-5-ynyl ketone system: Rapid assembly of cyclopenta[b]naphthalene and benzo[b]fluorene derivatives -
    [夏克山] 期刊論文 2012-12 Tandem cyclization of alpha-Cyano alpha-Alkynyl aryl ketones induced by tert-Butyl hydroperoxide and tetrabutylammonium iodide -
    [夏克山] 期刊論文 2012-11-20 Beckmann rearrangement of ketoximes induced by phenyl dichlorophosphate at ambient temperature -
    [夏克山] 期刊論文 2012-07 K2CO3/NaI-induced cyclization of omega-bromo alpha-cyano ketones: A new annulation approach for the formation of carbalkoxycyclohexane ring system -
    [夏克山] 期刊論文 2012-05 Palladium(II) acetate mediated oxidative cyclization of omega-unsaturated alpha-cyano ketones for facile construction of methylenecyclohexane ring system -
    [夏克山] 期刊論文 2012-02 Discovery of novel stem cell mobilizers that target the CXCR4 receptor -
    [夏克山] 期刊論文 2011-07 Conia-ene annulation of the alpha-cyano Beta-TMS-capped alkynyl cycloalkanone system and its synthetic application -
    [夏克山] 期刊論文 2011-06 Hot topic: Opportunities and potential challenges for the treatment of metabolic syndrome -
    [夏克山] 期刊論文 2011-03-04 Autoxidative annulation cascade of the alpha-cyano beta-TMS-capped alkynyl cycloalkanone system -
    [夏克山] 期刊論文 2010-09 Discovery of 1-(2,4-Dichlorophenyl)-4-ethyl-5-(5-(2-(4-(trifluoromethyl)phenyl)ethynyl)thiophe n-2-yl)-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide as a potential peripheral cannabinoid-1 receptor inverse agonist -
    [夏克山] 期刊論文 2010-08 Total synthesis of (-)-Isopisiferin: Confirmation of absolute configuration -
    [夏克山] 期刊論文 2010-06 General approach to 2,3-dibenzyl-gamma-butyrolactone lignans: application to the total synthesis of (+/-)-5 '-methoxyyatein, (+/-)-5 '-methoxyclusin, and (+/-)-4 '-hydroxycubebinone -
    [夏克山] 期刊論文 2010-02 Alpha-activated cross conjugated cycloalkenone systems in organic synthesis -
    [夏克山] 期刊論文 2009-07-23 Discovery of 2-[5-(4-chloro-phenyl)-1-(2,4-dichloro-phenyl)-4-ethyl-1H-pyrazol-3-yl]-1,5,5-trimethyl-1,5-dihydro-imidazol-4-thione (BPR-890) via an active metabolite. A novel, potent and selective cannabinoid-1 receptor inverse agonist with high antiobesity efficacy in DIO mice -
    [夏克山] 期刊論文 2009-04-16 Polyene cyclization promoted by the cross-conjugated alpha-carbalkoxy cyclohexenone system. An unusual 1,2-hydride shift under lewis acid catalysis -
    [夏克山] 期刊論文 2009 A concise total synthesis of (±)-acutifolone A -
    [夏克山] 期刊論文 2008-09-21 Bioisosteric replacement of the pyrazole 3-carboxamide moiety of rimonabant. A novel series of oxadiazoles as CB1 cannabinoid receptor antagonists -
    [夏克山] 期刊論文 2008-09-11 Bioisosteric replacement of the pyrazole 5-aryl moiety of N-(piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (SR141716A). A novel series of alkynylthiophenes as potent and selective cannabinoid-1 receptor antagonists -
    [夏克山] 期刊論文 2008-02-07 Design, synthesis, and biological evaluation of novel alkenylthiophenes as potent and selective CB1 cannabinoid receptor antagonists -
    [夏克山] 期刊論文 2008-01-03 Polyene cyclization promoted by the cross-conjugated alpha-carbalkoxy enone system. Observation on a putative 1,5-hydride/1,3-alkyl shift under Lewis acid catalysis -
    [夏克山] 期刊論文 2007-05-16 Lithium naphthalenide induced reductive selenenylation of alpha-cyano ketones: A regiocontrolled process for alpha-phenylseleno ketones and one-pot conversion into enone system -
    [夏克山] 期刊論文 2007-05-16 An efficient new procedure for the one-pot conversion of aldehydes into the corresponding nitriles -
    [夏克山] 期刊論文 2007 A convenient new procedure for converting primary amides into nitriles -
    [夏克山] 期刊論文 2005-04 Carbapenern-based prodrugs. Design, synthesis, and biological evaluation of carbapenems -
    [夏克山] 期刊論文 2005 Design, synthesis and biological evaluation of novel carbapenems -
    [夏克山] 期刊論文 2004-10-18 Synthesis and antienteroviral activity of a series of novel, oxime ether-containing pyridyl imidazolidinones -
    [夏克山] 期刊論文 2004-03-08 Synthesis and in vitro cytotoxicity of 5-substituted 2-cyanoimino-4-imidazodinone and 2-cyanoimino-4-pyrimidinone derivatives -
    [夏克山] 期刊論文 2003-02-17 A modified Robinson annulation process to alpha,alpha-disubstituted-beta,gamma-unsaturated cyclohexanone system. Application to the total synthesis of nanaimoal -
    [夏克山] 期刊論文 2002-10-07 Synthesis and anticancer evaluation of vitamin K-3 analogues -
    [夏克山] 期刊論文 2002 Diels-Alder chemistry of 2-diethoxyphosphinylcyclohex-2-enones. A new approach to complex phosphonates and synthetic applications of the beta-keto phosphonate system -
    [夏克山] 期刊論文 2001-11 An efficacious synthetic strategy for cis-clerodane diterpenoids. Application to the total synthesis of (+/-)-6 beta-acetoxy-2-oxokolavenool -
    [夏克山] 期刊論文 1999-06 Polyene cyclization promoted by the cross conjugated alpha-carbalkoxy enone system. An efficient approach to highly functionalized decalins -
    [張仲明] 會議論文/會議摘要 2002-08 Design, synthesis, and structure-activity relationship of pyridyl imidazolidinones: A novel class of potent and selective human enterovirus 71 inhibitors -
    [張俊彥] 期刊論文 2022-03-02 Discovery of potential neuroprotective agents against paclitaxel-induced peripheral neuropathy -
    [徐祖安] 期刊論文 2004-05-17 Design, synthesis, and structure-activity relationships of pyrazolo[3,4-d]pyrimidinies: a novel class of potent enterovirus inhibitors -
    [楊采菱] 期刊論文 2020-01-06 Biosynthetic engineering of the antifungal, anti-MRSA auroramycin -
    [洪明秀] 會議論文/會議摘要 2019-10 In vivo efficacy of cannabinoid receptor 1 antagonist, CPD1, in treating non-alcoholic fatty liver disease -
    [洪明秀] 期刊論文 2023-01 Modulating the affinity and signaling bias of cannabinoid receptor 1 antagonists -
    [洪明秀] 期刊論文 2015-05 A novel peripheral cannabinoid receptor 1 antagonist, BPR0912, reduces weight independently of food intake and modulates thermogenesis -
    [洪明秀] 期刊論文 2012-07 Induction of fatty acid oxidation resists weight gain, ameliorates hepatic steatosis and reduces cardiometabolic risk factors -
    [洪明秀] 期刊論文 2010-10 Biphasic suppression of appetite by cannabinoid CB1 receptor antagonists with distinct functional activities -
    [王昀] 期刊論文 2020-09-25 Protective effect of CXCR4 antagonist CX807 in a rat model of hemorrhagic stroke -
    [趙宇生(2002-2013)] 期刊論文 2004-09 Mutation in enterovirus 71 capsid protein VP1 confers resistance to the inhibitory effects of pyridyl imidazolidinone -
    [鄒倫] 期刊論文 2019-07-11 Linker optimization and therapeutic evaluation of phosphatidylserine-targeting zinc dipicolylamine-based drug conjugates -
    [鄒倫] 期刊論文 2019-05 Characterization, dynamics, and mechanism of CXCR4 antagonists on a constitutively active mutant -
    [鄒倫] 期刊論文 2017-07 Targeting tumor associated phosphatidylserine with new zinc dipicolylamine-based drug conjugates -
    [陳志豪] 專利 2006-08-01 抗腸病毒化合物 -
    [陳志豪] 專利 2004-11-09 Anti-enterovirus compounds -
    [陳志豪] 期刊論文 2002-04-11 Design, synthesis, and structure-activity relationship of pyridyl imidazolidinones: A novel class of potent and selective human enterovirus 71 inhibitors -
    [陳炯東] 會議論文/會議摘要 2015-08 Zinc-dipicolylamine directed pharmaceutical delivery system (ZAPS) as an innovative cancer drug delivery platform -

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