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Discovery of novel TANK-Binding Kin...
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Development of furanopyrimidine-bas...
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2024-12
Discovery of novel TANK-Binding Kinase 1 (TBK1) inhibitor against pancreatic ductal adenocarcinoma
International Journal of Biological Macromolecules. 2024 Dec;283(Part 1):Article number 137296.
2024-11
DBPR116, a prodrug of BPRMU191, in combination with naltrexone as a safer opioid analgesic than morphine via peripheral administration
Journal of Medicinal Chemistry. 2024 Nov 14;67(21):19777-19790.
2024-06-24
Macrophage-mediated controlled release of cysteine protease inhibitor from PLGA-PEG/hydroxyapatite microspheres for targeting cathepsin S in Alzheimer's disease
European Polymer Journal. 2024 Jun 24;214:Article number 113151.
2024-06-24
Discovery of dual MER/AXL kinase inhibitors as bifunctional small molecules for inhibiting tumor growth and enhancing tumor immune microenvironment
Journal of Medicinal Chemistry. 2024 Jun 24;Article in Press.
2024-05-09
Targeting cathepsin S promotes activation of OLF1-BDNF/TrkB axis to enhance cognitive function
Journal of Biomedical Science. 2024 May 09;31:Article number 46.
2023-11-03
Influence of ring strain on the formation of rearrangement vs cyclization isotwistane products in the acyl radical reaction of bicyclo[2.2.2]octanone
Organic Letters. 2023 Nov 3;25(43):7757-7762.
2023-10-05
A dual nociceptin and mu opioid receptor agonist exhibited robust antinociceptive effect with decreased side effects
European Journal of Medicinal Chemistry. 2023 Oct 05;258:Article number 115608.
2023-02-07
Development of furanopyrimidine-based orally active third-generation EGFR inhibitors for the treatment of non-small cell lung cancer
Journal of Medicinal Chemistry. 2023 Feb 7;66(4):2566-2588.
2022-09-12
A critical overview of current progress for COVID-19: Development of vaccines, antiviral drugs, and therapeutic antibodies
Journal of Biomedical Science. 2022 Sep 12;29:Article number 68.
2022-08-09
Recent advances in total synthesis of natural products by masked ortho-benzoquinones
Journal of the Chinese Chemical Society. 2022 Aug 09;69(8):1210-1222.
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