Collection 會議論文/會議摘要 [4/6] 期刊論文 [9/9] Siblings 伍素瑩 [52/65] 其他 [58/60] 夏克山 [76/98] 岳嶽 [29/32] 張仲明 [7/9] 張俊彥 [18/18] 張竣評 [21/26] 徐祖安 [170/215] 李秀珠 [75/105] 李靜琪 [23/24] 林書玉 [19/20] 洪明秀 [31/40] 潘秀玲(2009-2013) [16/17] 王鴻俊 [7/7] 石全(2014-2017) [35/39] 童俊維 [23/23] 紀雅惠 [21/25] 翁紹華 [22/24] 莊宏 [1/1] 葉修華 [24/25] 葉燈光 [133/152] 蔣維棠 [41/66] 謝興邦 [171/231] 趙宇生(2002-2013) [120/212] 郭靜娟 [49/55] 鄒倫 [28/29] 陳志豪 [31/52] 陳新(2002-2015) [53/67] 陳炯東 [180/212] 顏婉菁 [6/7] 許明珠(1997-2001) [3/10] 陳淑貞(1998-2001) [3/11] 陳華鍵(1997-2001) [9/9] Community Statistics 近3年內發表的文件:1(6.67%) 含全文筆數:13(86.67%) 文件下載次數統計 下載大於0次:13(100.00%) 下載大於100次:13(100.00%) 檔案下載總次數:8084(0.15%) 最後更新時間: 2024-12-01 03:13 Top Upload Loading... Top Download Loading... Recent Submissions BPR3P0128, a non-nucleoside RNA-dep... Discovery of an orally efficacious ... Discovery of 2,4-diaminopyrimidines... Optimization of furanopyrimidine-ba... Discovery of BPR1K871-a quinazoline... Discovery of BPR1K871, a quinazolin... Homology modeling of DFG-in FMS-lik... Efficient virtual screening using l... Anaplastic lymphoma kinase (ALK) in... Ligand efficiency based approach fo...

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Date	Title	Relation
2024-04	BPR3P0128, a non-nucleoside RNA-dependent RNA polymerase inhibitor, inhibits SARS-CoV-2 variants of concern and exerts synergistic antiviral activity in combination with remdesivir	Antimicrobial Agents and Chemotherapy. 2024 Apr 3;68(4):Article number e0095623
2021-06-16	Discovery of an orally efficacious MYC inhibitor for liver cancer using a GNMT-based high-throughput screening system and structure-activity relationship analysis	Journal of Medicinal Chemistry. 2021 Jun 16;64(13):8992-9009.
2017-04	Discovery of BPR1K871-a quinazoline based multi-kinase inhibitor for the treatment of AML and solid tumors: Rational design, synthesis, in vitro and in vivo evaluation	Abstracts of Papers of the American Chemical Society. 2017 Apr;253:Meeting Abstract 482.
2016-12	Discovery of BPR1K871, a quinazoline based, multi-kinase inhibitor for the treatment of AML and solid tumors: Rational design, synthesis, in vitro and in vivo evaluation	Oncotarget. 2016 Dec;7(52):86239-86256.
2016-11-29	Discovery of novel inhibitors of Aurora kinases with indazole scaffold: In silico fragment-based and knowledge-based drug design	European Journal of Medicinal Chemistry. 2016 Nov 29;124:186-199.
2015-08	Optimization of furanopyrimidine-based kinase inhibitors: Identification of a BTK kinase inhibitor for the treatment of B cell lymphoma	Abstracts of Papers of the American Chemical Society. 2015 Aug;250:Meeting Abstract 180.
2015-08	Discovery of 2,4-diaminopyrimidines bearing a unique pharmacophore as anaplastic lymphoma kinase inhibitors	Abstracts of Papers of the American Chemical Society. 2015 Aug;250:Meeting Abstract 182.
2015-06-29	Homology modeling of DFG-in FMS-like tyrosine kinase 3 (FLT3) and structure-based virtual screening for inhibitor identification	Scientific Reports. 2015 Jun 29;5:Article number 11702.
2014-10	Small-molecule EGFR tyrosine kinase inhibitors for the treatment of cancer	Expert Opinion on Investigational Drugs. 2014 Oct;23(10):1333-1348.
2014-08	Ligand efficiency based approach for efficient virtual screening of compound libraries	European Journal of Medicinal Chemistry. 2014 Aug;83:226-235.
2014-07	Anaplastic lymphoma kinase (ALK) inhibitors: A review of design and discovery	MedChemComm. 2014 Jul;5(9):1266-1279.
2014-03	Efficient virtual screening using ligand efficiency based approach	Abstracts of Papers - American Chemical Society. 2014 Mar;247:Article number 55-MEDI.
2013-04-07	Kinase-focused library: Design and synthesis of pyrimidines derivatives bearing amino substituents using high throughput parallel synthesis	Abstracts of Papers - American Chemical Society. 2013 Apr 7;245:Article number 298-MEDI
2013-04-07	3D-QSAR assisted drug design: Identification of a potent quinazoline based Aurora kinase inhibitor	Abstracts of Papers - American Chemical Society. 2013 Apr 7;245:Article number 87-MEDI.
2013-01	3D-QSAR-assisted drug design: Identification of a potent quinazoline-based aurora kinase inhibitor	ChemMedChem. 2013 Jan;8(1):136-148.

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