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生技與藥物研究所
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陳華鍵(1997-2001)
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Showing items 126-150 of 1008. (41 Page(s) Totally)
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Date
Title
Relation
2021-03-04
Targeting lysosomal cysteine protease cathepsin S reveals immunomodulatory therapeutic strategy for oxaliplatin-induced peripheral neuropathy
Theranostics. 2021 Mar 4;11(10):4672-4687.
2021-03-02
Total synthesis of landomycins Q and R and related core structures for exploration of the cytotoxicity and antibacterial properties
RSC Advances. 2021 Mar 2;11(16):9426-9432.
2021-03-01
Phase I dose escalation study of sorafenib plus S-1 for advanced solid tumors
Scientific Reports. 2021 Mar 1;11:Article number 4834.
2021-02-24
New insights into oral squamous cell carcinoma: From clinical aspects to molecular tumorigenesis
International Journal of Molecular Sciences. 2021 Feb 24;22(5):Article number 2252.
2021-02-22
Mimicking H3 substrate arginine in the design of G9a lysine methyltransferase inhibitors for cancer therapy: A computational study for structure-based drug design
ACS Omega. 2021 Feb 22;6(9):6100-6111.
2021-01-31
Briarenols W-Z: Chlorine-containing polyoxygenated briaranes from octocoral briareum stechei (Kükenthal, 1908)
Marine Drugs. 2021 Jan 31;19(2):Article number 77.
2021-01-15
One-pot synthesis of dibenzo[b,f]oxepines and total synthesis of bauhinoxepin C
Journal of Organic Chemistry. 2021 Jan 15;86(2):1955-1963.
2021-01
Overcoming vincristine resistance in cancer: Computational design and discovery of piperine-inspired P-glycoprotein inhibitors
Chemical Biology and Drug Design. 2021 Jan;97(1):51-66.
2021-01
Effect of a neuropilin-1-derived virus receptor trap on enterovirus A71 infection in vitro
Antimicrobial Agents and Chemotherapy. 2021 Jan;65(1):Article number e00695-20.
2021-01
BPRDP056, a novel small molecule drug conjugate specifically targeting phosphatidylserine for cancer therapy
Translational Oncology. 2021 Jan;14(1):Article number 100897.
2021-01
Potent and orally active purine-based fetal hemoglobin inducers for treating Beta-thalassemia and sickle cell disease
European Journal of Medicinal Chemistry. 2021 Jan;209:Article number 112938.
2020-12-14
Inhibition of SARS-CoV-2 by highly potent broad-spectrum anti-coronaviral tylophorine-based derivatives
Frontiers in Pharmacology. 2020 Dec 14;11:Article number 606097.
2020-12-10
Tumor-agnostic inhibitors in oncology: A new phase for precision medicine
Journal of the Chinese Chemical Society. 2020 Dec 10;67(12):2216-2224.
2020-12-03
Mitochondria and calcium homeostasis: Cisd2 as a big player in cardiac ageing
International Journal of Molecular Sciences. 2020 Dec 3;21(23):Article number 9238.
2020-12
Rosmarinic acid exhibits broad anti-enterovirus A71 activity by inhibiting the interaction between the five-fold axis of capsid VP1 and cognate sulfated receptors
Emerging Microbes and Infections. 2020 Dec;9(1):1194-1205.
2020-12
Natural cardenolides suppress coronaviral replication by downregulating JAK1 via a Na(+)/K(+)-ATPase independent proteolysis[Erratum:Biochemical Pharmacology. 2020 Oct;180:Article number 114122.]
Biochemical Pharmacology. 2020 Dec;182:Article number 114287.
2020-12
Engineering a novel IgG-like bispecific antibody against enterovirus A71
Biochemistry and Biophysics Reports. 2020 Dec;24:Article number 100860.
2020-11-28
Exercise and the Cisd2 prolongevity gene: Two promising strategies to delay the aging of skeletal muscle
International Journal of Molecular Sciences. 2020 Nov 28;21(23):Article number 9059.
2020-11
Molecular profiling of afatinib-resistant non-small cell lung cancer cells in vivo derived from mice
Pharmacological Research. 2020 Nov;161:Article number 105183.
2020-10-08
Comparative study between deep learning and QSAR classifications for TNBC inhibitors and novel GPCR agonist discovery
Scientific Reports. 2020 Oct 8;10:Article number 16771.
2020-10
Increased activation of HDAC1/2/6 and Sp1 underlies therapeutic resistance and tumor growth in glioblastoma
Neuro-Oncology. 2020 Oct;22(10):1439-1451.
2020-10
Natural cardenolides suppress coronaviral replication by downregulating JAK1 via a Na(+)/K(+)-ATPase independent proteolysis
Biochemical Pharmacology. 2020 Oct;180:Article number 114122.
2020-10
A bubble bursting-mediated oral drug delivery system that enables concurrent delivery of lipophilic and hydrophilic chemotherapeutics for treating pancreatic tumors in rats
Biomaterials. 2020 Oct;255:Article number 120157.
2020-09-25
Protective effect of CXCR4 antagonist CX807 in a rat model of hemorrhagic stroke
International Journal of Molecular Sciences. 2020 Sep 25;21(19):Article number 7085.
2020-08-20
Discovery of M protease inhibitors encoded by SARS-CoV-2
Antimicrobial Agents and Chemotherapy. 2020 Aug 20;64(9):e00872-20.
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