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顯示項目1-50 / 98. (共2頁) 1 2 > >> 每頁顯示[10|25|50]項目

日期	題名	關聯
2023-03-17	A convenient diels-alder approach toward potential polyketide-like antibiotics using alpha-activated alpha,Beta-unsaturated 4,4-dimethyl-1-tetralones as dienophiles	Molecules. 2023 Mar 17;28(6):Article number 2739.
2023-01	Modulating the affinity and signaling bias of cannabinoid receptor 1 antagonists	Bioorganic Chemistry. 2023 Jan;130:Article number 106236.
2022-10-03	Protective effect of CXCR4 antagonist DBPR807 against ischemia-reperfusion injury in a rat and porcine model of myocardial infarction: Potential adjunctive therapy for percutaneous coronary intervention	International Journal of Molecular Sciences. 2022 Oct 3;23(19):Article number 11730.
2022-03-02	Discovery of potential neuroprotective agents against paclitaxel-induced peripheral neuropathy	Journal of Medicinal Chemistry. 2022 Mar 2;65(6):4767-4782.
2021-07-21	Anionic diels-alder chemistry of cyclic sodium dien-1-olates delivering highly stereoselective and functionalized polycyclic adducts	Organic Letters. 2021 Jul 21;23(15):5709-5713.
2021-03-30	A highly selective and potent CXCR4 antagonist for hepatocellular carcinoma treatment	Proceedings of the National Academy of Sciences of the United States of America. 2021 Mar 30;118(13):Article number e2015433118.
2021-03-02	Total synthesis of landomycins Q and R and related core structures for exploration of the cytotoxicity and antibacterial properties	RSC Advances. 2021 Mar 2;11(16):9426-9432.
2020-09-25	Protective effect of CXCR4 antagonist CX807 in a rat model of hemorrhagic stroke	International Journal of Molecular Sciences. 2020 Sep 25;21(19):Article number 7085.
2020-04	Development of a cross-conjugated vinylogous [4+2] anionic annulation and application to the total synthesis of natural antibiotic (±)-ABX	Angewandte Chemie. 2020 Apr;59(16):6540-6545.
2020-02-10	Unique sulfur-aromatic interactions contribute to the binding of potent imidazothiazole indoleamine 2,3-Dioxygenase inhibitors	Journal of Medicinal Chemistry. 2020 Feb 10;63(4):1642-1659.
2020-01-16	Development of a cross-conjugated vinylogous [4+2] anionic annulation and application to the total synthesis of natural antibiotic (±)-ABX	Advanced Materials. 2020 Jan 16;132(16):6602-6607.
2020-01-06	Biosynthetic engineering of the antifungal, anti-MRSA auroramycin	Microbial Cell Factories. 2020 Jan 6;19:Article number 3.
2019-10	In vivo efficacy of cannabinoid receptor 1 antagonist, CPD1, in treating non-alcoholic fatty liver disease	Hepatology. 2019 Oct;70:1333A.
2019-07-11	Linker optimization and therapeutic evaluation of phosphatidylserine-targeting zinc dipicolylamine-based drug conjugates	Journal of Medicinal Chemistry. 2019 Jul 11;62(13):6047-6062.
2019-05	Characterization, dynamics, and mechanism of CXCR4 antagonists on a constitutively active mutant	Cell Chemical Biology. 2019 May;26(5):662-673.e7.
2019-01-01	Fluorine-18 isotope labeling for positron emission tomography imaging. Direct evidence for DBPR211 as a peripherally restricted CB1 inverse agonist	Bioorganic and Medicinal Chemistry. 2019 Jan 1;27(1):216-223.
2018-12-07	Temperature-controlled thiation of alpha-Cyano-beta-Alkynyl carbonyl derivatives for de vovo synthesis of 2-Aminothiophenes and thieno[2,3- c]isothiazoles	Journal of Organic Chemistry. 2018 Dec 7;83(23):14688-14697.
2018-08	Auroramycin: A potent antibiotic from streptomyces roseosporus by CRISPR-Cas9 activation	Chembiochem: A European Journal of Chemical Biology. 2018 Aug;19(16):1716-1719.
2018-07	Harnessing CXCR4 antagonists in stem cell mobilization, HIV infection, ischemic diseases, and oncology	Medicinal Research Reviews. 2018 Jul;38(4):1188-1234.
2018-07	Synergic effect of curcumin and its structural analogue (Monoacetylcurcumin) on anti-influenza virus infection	Journal of Food and Drug Analysis. 2018 Jul;26(3):1015-1023.
2018-05-22	Total synthesis of tetarimycin A, (±)-Naphthacemycin A9, and (±)-Fasamycin A: structure-activity relationship studies against drug-resistant bacteria	Journal of Organic Chemistry. 2018 May 22;83(12):6508-6523.
2018-02-08	Development of stem-cell-mobilizing agents targeting CXCR4 receptor for peripheral blood stem cell transplantation and beyond	Journal of Medicinal Chemistry. 2018 Feb 8;61(3):818-833.
2017-07	Targeting tumor associated phosphatidylserine with new zinc dipicolylamine-based drug conjugates	Bioconjugate Chemistry. 2017 Jul;28(7):1878-1892.
2017-04	A novel CXCR4 antagonist CX549 induces neuroprotection in stroke brain	Cell Transplantation. 2017 Apr;26(4):571-583.
2016-12-08	Bromomethylthioindole inspired carbazole hybrids as promising class of anti-MRSA agents	ACS Medicinal Chemistry Letters. 2016 Dec 8;7(12):1191-1196.
2016-11-18	Cobalt(II)-catalyzed aerobic oxidation of terminal-capped alkynyl alpha-cyano alkanone systems. An oxygen-mediated radical chain reaction	Journal of Organic Chemistry. 2016 Nov 18;81(22):10759-10768.
2016-01	Synthesis of (E)-oxindolylidene acetate using tandem palladium-catalyzed Heck and alkoxycarbonylation reactions	Organic and Biomolecular Chemistry. 2016 Jan;14(1):220-228.
2016-01	Important hydrogen bond networks in Indoleamine 2,3-Dioxygenase 1 (IDO1) inhibitor design revealed by crystal structures of imidazoleisoindole derivatives with IDO1	Journal of Medicinal Chemistry. 2016 Jan;59 (1):282-293.
2015-08-14	Studies on antibiotics active against resistant bacteria. Total synthesis of MRSA-active tetarimycin A and its analogues	Organic Letters. 2015 Aug 14;17(17):4248-4251.
2015-08	Zinc-dipicolylamine directed pharmaceutical delivery system (ZAPS) as an innovative cancer drug delivery platform	Cancer Research. 2015 Aug;75(Suppl. 15):Abstract number 4413.
2015-06-15	Synthesis and evaluation of 3-ylideneoxindole acetamides as potent anticancer agents	European Journal of Medicinal Chemistry. 2015 Jun 15;98:1-12.
2015-06-15	The total synthesis of retrojusticidin B, justicidin E, and helioxanthin	Journal of Organic Chemistry. 2015 Jun 15;80(13):6708-6714.
2015-05	A novel peripheral cannabinoid receptor 1 antagonist, BPR0912, reduces weight independently of food intake and modulates thermogenesis	Diabetes, Obesity and Metabolism. 2015 May;17(5):495-504.
2015-03	Stem cell mobilizers targeting chemokine receptor CXCR4: Renoprotective application in acute kidney injury	Journal of Medicinal Chemistry. 2015 Mar;58(5):2315-2325.
2015-02-24	Pyrazole compounds	US8962845/2015-02-24
2015-02-11	吡唑類化合物	I472514/2015-02-11
2015-02	Function-oriented development of CXCR4 antagonists as selective human immunodeficiency virus (HIV)-1 entry inhibitors	Journal of Medicinal Chemistry. 2015 Feb;58(3):1452-1465.
2014-11-19	咪唑-4-酮及咪唑-4-硫酮化合物	ZL200910006503.9/2014-11-19
2014-10	Manganese(III)-catalyzed oxidative cyclization of aryl 1-cyanoalk-5-ynyl ketone systems: A convenient and general approach to cyclopenta[b]naphthalene derivatives	Advanced Synthesis and Catalysis. 2014 Oct;356(14-15):3025-3038.
2014-07-30	Pyrazole compounds	ZA201303800B/2014-07-30
2014-04-21	咪唑-4-酮及咪唑-4-硫酮化合物	I434686/2014-04-21
2014-03	Double michael addition reactions of the nazarov reagent with 2-cyano-2-cycloalkenones: An alternative approach to cis-fused bicyclic systems	Synlett. 2014 Mar;25(4):543-546.
2013-11-13	Discovery of 1-(2,4-Dichlorophenyl)-N-(piperidin-1-yl)-4-((pyrrolidine-1-sulfonamido)methyl)-5 -(5-((4-(trifluoromethyl)phenyl)ethynyl)thiophene-2-yl)-1H-pyrazole-3-carboxamide as a novel peripherally restricted cannabinoid-1 receptor antagonist with significant weight-loss efficacy in diet-induced obese mice	Journal of Medicinal Chemistry. 2013 Nov 13;56(24):9920-9933.
2013-09-11	噻吩化合物及其醫藥組成物	I408136/2013-09-11
2013-04	Palladium(0)/copper(I)-catalyzed tandem cyclization of aryl 1-cyanoalk-5-ynyl ketone system: Rapid assembly of cyclopenta[b]naphthalene and benzo[b]fluorene derivatives	Advanced Synthesis and Catalysis. 2013 Apr;355(7):1323-1337.
2013-03-27	Thiophene compounds	EP2068870/2013-03-27
2013-01-15	Imidazol-4-one and imidazole-4-thione compounds	US8354442B2/2013-01-15
2012-12	Tandem cyclization of alpha-Cyano alpha-Alkynyl aryl ketones induced by tert-Butyl hydroperoxide and tetrabutylammonium iodide	Organic Letters. 2012 Dec;14(23):6024-6027.
2012-11-20	Beckmann rearrangement of ketoximes induced by phenyl dichlorophosphate at ambient temperature	Molecules. 2012 Nov 20;17(11):13662-13672.
2012-07-04	噻吩化合物	ZL200780036897.1/2012-07-04

顯示項目1-50 / 98. (共2頁) 1 2 > >> 每頁顯示[10|25|50]項目