國家衛生研究院 NHRI:
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    近3年内发表的文件:5(11.11%)
    含全文笔数:25(55.56%)

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    最后更新时间: 2025-05-01 04:41

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    日期题名關聯
    2025-02 Development of BACE2-IN-1/tranylcypromine-based compounds to induce steroidogenesis-dependent neuroprotection Biomedicine and Pharmacotherapy. 2025 Feb;183:Article number 117851.
    2024-11-21 Discovery of a mu-opioid receptor modulator that in combination with morphinan antagonists induces analgesia Cell Chemical Biology. 2024 Nov 21;31(11):1885-1898.e10.
    2024-11 DBPR116, a prodrug of BPRMU191, in combination with naltrexone as a safer opioid analgesic than morphine via peripheral administration Journal of Medicinal Chemistry. 2024 Nov 14;67(21):19777-19790.
    2024-05-01 Thiazolidinone compounds and use thereof EP3426246/2024-05-01
    2023-10-05 A dual nociceptin and mu opioid receptor agonist exhibited robust antinociceptive effect with decreased side effects European Journal of Medicinal Chemistry. 2023 Oct 05;258:Article number 115608.
    2022-12-05 Benzo[b]thiophene-2-carboxamides as novel opioid receptor agonists with potent analgesic effect and reduced constipation European Journal of Medicinal Chemistry. 2022 Dec 5;243:Article number 114728.
    2022-11-22 オピオイド受容体調節因子及びその使用 JP7181536/2022-11-22
    2022-11 Selective and antagonist-dependent µ-opioid receptor activation by the combination of 2-{[2-(6-chloro-3,4-dihydro-1(2H)-quinolinyl)-2-oxoethyl]sulfanyl}-5-phenyl-4,6-(1H,5H)-pyrimidinedione and naloxone/naltrexone Bioorganic Chemistry. 2022 Nov;128:Article number 105905.
    2022-08-30 チアゾリジノン化合物及びその使用 JP7132849/2022-08-30
    2022-05-20 噻唑烷酮化合物及其用途 HK1258687/2022-05-20
    2022-03-08 Opioid receptor modulators and use thereof CA2996281/2022-03-08
    2022-02-16 티아졸리디논 화합물 및 그의 용도 KR10-2365673/2022-02-16
    2022-01-19 噻唑烷酮化合物及其用途 J/005474/2022-01-19
    2022-01-05 阿片受體調節劑及其用途 J/005174/2022-01-05
    2021-09-28 噻唑烷酮化合物及其用途 CN108883099/2021-09-28
    2021-09-24 阿片受體調節劑及其用途 HK1253294/2021-09-24
    2021-07-22 Thiazolidinone compounds and use thereof AU2017229129/2021-07-22
    2021-06-04 阿片受体调节剂及其用途 CN108369222/2021-06-04
    2020-11-18 Opioid receptor modulators and use thereof EP3344997/2020-11-18
    2020-10-08 Comparative study between deep learning and QSAR classifications for TNBC inhibitors and novel GPCR agonist discovery Scientific Reports. 2020 Oct 8;10:Article number 16771.
    2020-10 Increased activation of HDAC1/2/6 and Sp1 underlies therapeutic resistance and tumor growth in glioblastoma Neuro-Oncology. 2020 Oct;22(10):1439-1451.
    2020-06 Morphine produces potent antinociception, sedation, and hypothermia in humanized mice expressing human mu opioid receptor splice variants Pain. 2020 Jun;161(6):1177-1190.
    2020-04-21 噻唑烷酮化合物及其用途 TWI691332/2020-04-21
    2020-04-15 Betulinic acid-mediated tuning of PERK/CHOP signaling by Sp1 inhibition as a novel therapeutic strategy for glioblastoma Cancers. 2020 Apr 15;12(4):Article number 981.
    2020-04 BPR1M97, a dual mu opioid receptor/nociceptin-orphanin FQ peptide receptor agonist, produces potent antinociceptive effects with safer properties than morphine Neuropharmacology. 2020 Apr;166:Article number 107678.

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