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2024-06-01
Discovery of a long half-life AURKA inhibitor to treat MYC-amplified solid tumors as a monotherapy and in combination with everolimus
Molecular Cancer Therapeutics. 2024 Jun 01;23(6):766-779.
2023-12
Pulmonary delivery of remdesivir and dexamethasone encapsulated nanostructured lipid carriers for enhanced inflammatory suppression in lung
Journal of Drug Delivery Science and Technology. 2023 Dec;90:Article number 105144.
2023-01
Modulating the affinity and signaling bias of cannabinoid receptor 1 antagonists
Bioorganic Chemistry. 2023 Jan;130:Article number 106236.
2021-06-11
Synergistic inhibition of SARS-CoV-2 replication using disulfiram/ebselen and remdesivir[Erratum:ACS Pharmacology and Translational Science. 2021 Apr 9;4(2):898-907.]
ACS Pharmacology and Translational Science. 2021 Jun 11;4(3):Article number 1246.
2021-05-19
Discovery and synthesis of a pyrimidine-based aurora kinase inhibitor to reduce levels of MYC oncoproteins
Journal of Medicinal Chemistry. 2021 May 19;64(11):7312-7330.
2021-04-09
Synergistic inhibition of SARS-CoV-2 replication using disulfiram/ebselen and remdesivir
ACS Pharmacology and Translational Science. 2021 Apr 9;4(2):898-907.
2020-12-14
Inhibition of SARS-CoV-2 by highly potent broad-spectrum anti-coronaviral tylophorine-based derivatives
Frontiers in Pharmacology. 2020 Dec 14;11:Article number 606097.
2020-10-08
Comparative study between deep learning and QSAR classifications for TNBC inhibitors and novel GPCR agonist discovery
Scientific Reports. 2020 Oct 8;10:Article number 16771.
2020-08
BPR6K609: An Aurora kinase inhibitor targeting small cell lung cancer with MYC amplification
Cancer Research. 2020 Aug;80(16):1937.
2019-07
An Aurora kinase inhibitor BPR6K471 inhibits tumor growth and reduces the cancer stem cell-like properties of small cell lung cancer
Cancer Research. 2019 Jul;79(13, Suppl.):Abstract number 3851.
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