國家衛生研究院 NHRI:
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    近3年内发表的文件:3(7.89%)
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    最后更新时间: 2025-02-26 18:53

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    显示项目1-25 / 38. (共2页)
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    日期题名關聯
    2024-06-01 Discovery of a long half-life AURKA inhibitor to treat MYC-amplified solid tumors as a monotherapy and in combination with everolimus Molecular Cancer Therapeutics. 2024 Jun 01;23(6):766-779.
    2023-12 Pulmonary delivery of remdesivir and dexamethasone encapsulated nanostructured lipid carriers for enhanced inflammatory suppression in lung Journal of Drug Delivery Science and Technology. 2023 Dec;90:Article number 105144.
    2023-01 Modulating the affinity and signaling bias of cannabinoid receptor 1 antagonists Bioorganic Chemistry. 2023 Jan;130:Article number 106236.
    2021-08-29 Pyrazole compounds AE3821/2021-08-29
    2021-06-11 Synergistic inhibition of SARS-CoV-2 replication using disulfiram/ebselen and remdesivir[Erratum:ACS Pharmacology and Translational Science. 2021 Apr 9;4(2):898-907.] ACS Pharmacology and Translational Science. 2021 Jun 11;4(3):Article number 1246.
    2021-05-19 Discovery and synthesis of a pyrimidine-based aurora kinase inhibitor to reduce levels of MYC oncoproteins Journal of Medicinal Chemistry. 2021 May 19;64(11):7312-7330.
    2021-04-09 Synergistic inhibition of SARS-CoV-2 replication using disulfiram/ebselen and remdesivir ACS Pharmacology and Translational Science. 2021 Apr 9;4(2):898-907.
    2020-12-14 Inhibition of SARS-CoV-2 by highly potent broad-spectrum anti-coronaviral tylophorine-based derivatives Frontiers in Pharmacology. 2020 Dec 14;11:Article number 606097.
    2020-10-08 Comparative study between deep learning and QSAR classifications for TNBC inhibitors and novel GPCR agonist discovery Scientific Reports. 2020 Oct 8;10:Article number 16771.
    2020-08 BPR6K609: An Aurora kinase inhibitor targeting small cell lung cancer with MYC amplification Cancer Research. 2020 Aug;80(16):1937.
    2019-10-22 Compostos e composição farmacêutica BR112013013490/2019-10-22
    2019-07 An Aurora kinase inhibitor BPR6K471 inhibits tumor growth and reduces the cancer stem cell-like properties of small cell lung cancer Cancer Research. 2019 Jul;79(13, Suppl.):Abstract number 3851.
    2019-01-01 Fluorine-18 isotope labeling for positron emission tomography imaging. Direct evidence for DBPR211 as a peripherally restricted CB1 inverse agonist Bioorganic and Medicinal Chemistry. 2019 Jan 1;27(1):216-223.
    2018-11-07 Pyrazole compounds EP2632919/2018-11-07
    2018-05-10 Design and synthesis of BPR1K653 derivatives targeting the back pocket of Aurora kinases for selective isoform inhibition European Journal of Medicinal Chemistry. 2018 May 10;151:533-545.
    2018-03-29 吡唑類化合物 HK1187610/2018-03-29
    2016-12-08 Bromomethylthioindole inspired carbazole hybrids as promising class of anti-MRSA agents ACS Medicinal Chemistry Letters. 2016 Dec 8;7(12):1191-1196.
    2016-11-23 吡唑類化合物 J/002325/2016-11-23
    2016-10-27 Pyrazole derivatives RU2600983/2016-10-27
    2016-06-22 吡唑类化合物 CN103459383/2016-06-22
    2016-06-09 Pyrazole compounds AU2012316331/2016-06-09
    2016-05-10 Pyrazole compounds CA2818944/2016-05-10
    2016-01-22 ピラゾール化合物 JP5872591/2016-01-22
    2016-01-13 피라졸 화합물 KR10-1586714/2016-01-13
    2015-05 A novel peripheral cannabinoid receptor 1 antagonist, BPR0912, reduces weight independently of food intake and modulates thermogenesis Diabetes, Obesity and Metabolism. 2015 May;17(5):495-504.

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