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    最後更新時間: 2025-04-28 15:53

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    日期題名關聯
    2025-02-27 Orally bioavailable and site-selective covalent STING inhibitor derived from a macrocyclic marine diterpenoid Journal of Medicinal Chemistry. 2025 Feb 27;Article in Press.
    2024-06-01 Discovery of a long half-life AURKA inhibitor to treat MYC-amplified solid tumors as a monotherapy and in combination with everolimus Molecular Cancer Therapeutics. 2024 Jun 01;23(6):766-779.
    2023-11-15 Analysis of structure–activity relationship of indol-3-yl-N-phenylcarbamic amides as potent STING inhibitors Bioorganic and Medicinal Chemistry. 2023 Nov 15;95:Article number 117502.
    2023-07-18 Marine diterpenoid targets STING palmitoylation in mammalian cells Communications Chemistry. 2023 Jul 18;6:Article number 153.
    2022-08 AKT phosphorylation as a predictive biomarker for PI3K/mTOR dual inhibition-induced proteolytic cleavage of mTOR companion proteins in small cell lung cancer Cell and Bioscience. 2022 Aug;12:Article number 122.
    2022-07-11 嘧啶化合物及其醫藥用途 TWI770858/2022-07-11
    2022-02-16 티아졸리디논 화합물 및 그의 용도 KR10-2365673/2022-02-16
    2022-01-04 Deformation of the nucleus by TGF beta 1 via the remodeling of nuclear envelope and histone isoforms Epigenetics and Chromatin. 2022 Jan 04;15:Article number 1.
    2021-06-02 Development of a respiratory syncytial virus vaccine using human hepatitis B core-based virus-like particles to induce mucosal immunity Vaccine. 2021 Jun 2;39(24):3259-3269.
    2021-05-19 Discovery and synthesis of a pyrimidine-based aurora kinase inhibitor to reduce levels of MYC oncoproteins Journal of Medicinal Chemistry. 2021 May 19;64(11):7312-7330.
    2021-03-08 The SUN2-nesprin-2 LINC complex and KIF20A function in the Golgi dispersal Scientific Reports. 2021 Mar 8;11:Article number 5358.
    2020-11-28 Exercise and the Cisd2 prolongevity gene: Two promising strategies to delay the aging of skeletal muscle International Journal of Molecular Sciences. 2020 Nov 28;21(23):Article number 9059.
    2020-08-19 Lamin A-mediated nuclear lamina integrity is required for proper ciliogenesis EMBO Reports. 2020 Oct 05;21(10):Article number e49680.
    2020-08 BPR6K609: An Aurora kinase inhibitor targeting small cell lung cancer with MYC amplification Cancer Research. 2020 Aug;80(16):1937.
    2019-12 Progerin in muscle leads to thermogenic and metabolic defects via impaired calcium homeostasis Aging Cell. 2019 Dec;Article number e13090.
    2019-08-15 Sun1 mediates interkinetic nuclear migration and Notch signaling in the neurogenesis of zebrafish Stem Cells and Development. 2019 Aug 15;28(16):1116-1127.
    2019-07 An Aurora kinase inhibitor BPR6K471 inhibits tumor growth and reduces the cancer stem cell-like properties of small cell lung cancer Cancer Research. 2019 Jul;79(13, Suppl.):Abstract number 3851.
    2019-05 A novel mechanism of miRNA-mediated CBX8 associated with tumorigenesis in head and neck squamous cell carcinoma Journal of Clinical Oncology. 2019 May;37(15, Suppl. S):Abstract number e17534.
    2019-03-01 Interference of DNAJB6/MRJ isoform switch by morpholino inhibits replication of HIV-1 and RSV Molecular Therapy. Nucleic Acids. 2019 Mar 1;14:251-261.
    2018-05-10 Design and synthesis of BPR1K653 derivatives targeting the back pocket of Aurora kinases for selective isoform inhibition European Journal of Medicinal Chemistry. 2018 May 10;151:533-545.
    2017-09 Outer nuclear membrane protein Kuduk modulates the LINC complex and nuclear envelope architecture Journal of Cell Biology. 2017 Sep;216(9):2827-2841.
    2017-09 Adaptation of influenza A (H7N9) virus in primary human airway epithelial cells Scientific Reports. 2017 Sep;7:Article number 11300.
    2017-08-07 Utrophin compensates dystrophin loss during mouse spermatogenesis Scientific Reports. 2017 Aug 7;7:Article number 7372.
    2017-04-05 In vivo inhibition of influenza A virus replication by RNA interference targeting the PB2 subunit via intratracheal delivery PLoS ONE. 2017 Apr 5;12(4):Article number e0174523.
    2015-08 Sun1 deficiency leads to cerebellar ataxia in mice Disease Models and Mechanisms. 2015 Aug;8(8):957-967.

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