國家衛生研究院 NHRI:作者相关文件

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"Yeh, T. K."的相关文件

类别	日期	题名	關聯
[伍素瑩] 期刊論文	2020-02-10	Unique sulfur-aromatic interactions contribute to the binding of potent imidazothiazole indoleamine 2,3-Dioxygenase inhibitors	-
[伍素瑩] 期刊論文	2019-04-10	Discovery of Conformational Control Inhibitors Switching off the Activated c-KIT and Targeting a Broad Range of Clinically Relevant c-KIT Mutants	-
[伍素瑩] 期刊論文	2015-10	Identification of substituted naphthotriazolediones as novel tryptophan 2,3-dioxygenase (TDO) inhibitors through structure-based virtual screening	-
[其他] 期刊論文	2022-07-24	Hesperetin promotes longevity and delays aging via activation of Cisd2 in naturally aged mice	-
[劉滄梧] 期刊論文	2020-02-18	Impacts of intralipid on nanodrug abraxane therapy and on the innate immune system	-
[夏克山] 專利	2014-11-19	咪唑-4-酮及咪唑-4-硫酮化合物	-
[夏克山] 專利	2014-04-21	咪唑-4-酮及咪唑-4-硫酮化合物	-
[夏克山] 專利	2013-01-15	Imidazol-4-one and imidazole-4-thione compounds	-
[夏克山] 期刊論文	2022-10-03	Protective effect of CXCR4 antagonist DBPR807 against ischemia-reperfusion injury in a rat and porcine model of myocardial infarction: Potential adjunctive therapy for percutaneous coronary intervention	-
[夏克山] 期刊論文	2021-03-30	A highly selective and potent CXCR4 antagonist for hepatocellular carcinoma treatment	-
[夏克山] 期刊論文	2018-02-08	Development of stem-cell-mobilizing agents targeting CXCR4 receptor for peripheral blood stem cell transplantation and beyond	-
[夏克山] 期刊論文	2013-11-13	Discovery of 1-(2,4-Dichlorophenyl)-N-(piperidin-1-yl)-4-((pyrrolidine-1-sulfonamido)methyl)-5 -(5-((4-(trifluoromethyl)phenyl)ethynyl)thiophene-2-yl)-1H-pyrazole-3-carboxamide as a novel peripherally restricted cannabinoid-1 receptor antagonist with significant weight-loss efficacy in diet-induced obese mice	-
[夏克山] 期刊論文	2010-09	Discovery of 1-(2,4-Dichlorophenyl)-4-ethyl-5-(5-(2-(4-(trifluoromethyl)phenyl)ethynyl)thiophe n-2-yl)-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide as a potential peripheral cannabinoid-1 receptor inverse agonist	-
[夏克山] 期刊論文	2009-07-23	Discovery of 2-[5-(4-chloro-phenyl)-1-(2,4-dichloro-phenyl)-4-ethyl-1H-pyrazol-3-yl]-1,5,5-trimethyl-1,5-dihydro-imidazol-4-thione (BPR-890) via an active metabolite. A novel, potent and selective cannabinoid-1 receptor inverse agonist with high antiobesity efficacy in DIO mice	-
[岳嶽] 期刊論文	2013-02	Resistance studies of a di-thiazol analogue, DBPR110, as a potential hepatitis C virus NS5A inhibitor in replicon systems	-
[岳嶽] 期刊論文	2012-01	Resistance analysis and characterization of a thiazole analogue, BP008, as a potent hepatitis C virus NS5A inhibitor	-
[廖玉潔] 期刊論文	2024-08-19	Tracing the footprints of MPXV in Asia: Phylogenetic insights and lineage dynamics	-
[張俊彥] 期刊論文	2022-03-02	Discovery of potential neuroprotective agents against paclitaxel-induced peripheral neuropathy	-
[張俊彥] 期刊論文	2018-06-15	2-Aroylquinoline-5,8-diones as potent anticancer agents displaying tubulin and heat shock protein 90 (HSP90) inhibition [Erratum: Organic and Biomolecular Chemistry. 2016 Jan;14(2):716-723.]	-
[張俊彥] 期刊論文	2016-01	2-Aroylquinoline-5,8-diones as potent anticancer agents displaying tubulin and heat shock protein 90 (HSP90) inhibition	-
[張俊彥] 期刊論文	2014-05	Azaindolylsulfonamides, with a more selective inhibitory effect on histone deacetylase 6 activity, exhibit antitumor activity in colorectal cancer HCT116 cells	-
[張俊彥] 期刊論文	2014-04	Antimitotic and vascular disrupting agents: 2-hydroxy-3,4,5-trimethoxybenzophenones	-
[張俊彥] 期刊論文	2011-08	BPR1K653, a novel aurora kinase inhibitor, exhibits potent anti-proliferative activity in MDR1 (P-gp170)-mediated multidrug-resistant cancer cells	-
[張俊彥] 期刊論文	2009-04-17	Synthesis and structure-activity relationships of 1-benzyl-4,5,6-trimethoxyindoles as a novel class of potent antimitotic agents	-
[徐祖安] 會議論文/會議摘要	2014-03	DBPR112, a potent and selective EGFR kinase inhibitor in preclinical study	-
[徐祖安] 會議論文/會議摘要	2011-03	Potent EGFR tyrosine kinase inhibitors as anticancer agents	-
[徐祖安] 期刊論文	2014-01-08	Evaluation of the antitumor effects of BPR1J-340, a potent and selective FLT3 inhibitor, alone or in combination with an HDAC inhibitor, vorinostat, in AML cancer	-
[徐祖安] 期刊論文	2012-01	BPR1J-097, a novel FLT3 kinase inhibitor, exerts potent inhibitory activity against AML	-
[李秀珠] 會議論文/會議摘要	2013-04-13	Exploration of the role of tylophorine E ring in anti-Coronavirus activity-Tylophorine derived dibenzoquinolines impart multi-biological activities as orally active agents	-
[李秀珠] 期刊論文	2020-08	Repurposing old drugs as antiviral agents for coronaviruses	-
[李秀珠] 期刊論文	2017-07	Design, synthesis, and evaluation of thiazolidine-2,4-dione derivatives as a novel class of glutaminase inhibitors	-
[李靜琪] 期刊論文	2023-10-05	Discovery of tetrasubstituted thiophenes as Cisd2 activators: A potential novel therapeutic option in nonalcoholic fatty liver disease	-
[李靜琪] 期刊論文	2019-03	Synthesis and biological evaluation of N-glucosyl indole derivatives as sodium-dependent glucose co-transporter 2 inhibitors	-
[李靜琪] 期刊論文	2018-01-01	Identification of an oxime-containing C-glucosylarene as a potential inhibitor of sodium-dependent glucose co-transporter 2	-
[李靜琪] 期刊論文	2016-05	N-Indolylglycosides bearing modifications at the glucose C6-Position as Sodium-Dependent Glucose Co-transporter 2 inhibitors	-
[李靜琪] 期刊論文	2012-09	Synthesis and biological evaluation of novel C-indolylxylosides as sodium-dependent glucose co-transporter 2 inhibitors	-
[林嬪嬪] 會議論文/會議摘要	2007-10	Differential effects of arsenic on cyp1 enzymes in vitro and in vivo	-
[林嬪嬪] 期刊論文	2009-02	Involvement of oxidative stress and activation of aryl hydrocarbon receptor in elevation of CYP1A1 expression and activity in lung cells and tissues by arsenic: An in vitro and in vivo study	-
[林嬪嬪] 期刊論文	2007-09	Persistent tissue kinetics and redistribution of nanoparticles, quantum dot 705, in mice: ICP-MS quantitative assessment	-
[楊重熙] 期刊論文	2011-03	Comparative tissue distributions of cadmium chloride and cadmium-based quantum dot 705 in mice: Safety implications and applications	-
[洪明秀] 會議論文/會議摘要	2016-12	Phenyl benzenesulfonylhydrazides: Selective indoleamine 2,3-dioxygenase inhibitors with potent in vivo pharmacodynamic activity and antitumor efficacy	-
[洪明秀] 期刊論文	2010-10	Biphasic suppression of appetite by cannabinoid CB1 receptor antagonists with distinct functional activities	-
[石全(2014-2017)] 會議論文/會議摘要	2020-08	BPR6K609: An Aurora kinase inhibitor targeting small cell lung cancer with MYC amplification	-
[紀雅惠] 會議論文/會議摘要	2019-07	An Aurora kinase inhibitor BPR6K471 inhibits tumor growth and reduces the cancer stem cell-like properties of small cell lung cancer	-
[紀雅惠] 期刊論文	2024-06-01	Discovery of a long half-life AURKA inhibitor to treat MYC-amplified solid tumors as a monotherapy and in combination with everolimus	-
[紀雅惠] 期刊論文	2021-05-19	Discovery and synthesis of a pyrimidine-based aurora kinase inhibitor to reduce levels of MYC oncoproteins	-
[翁紹華] 會議論文/會議摘要	2018-07	4-Bromophenylhydrazinyl benzenesulfonylphenylureas inhibit indoleamine 2,3-dioxygenase in vitro and in vivo	-
[翁紹華] 期刊論文	2022-12-05	Benzo[b]thiophene-2-carboxamides as novel opioid receptor agonists with potent analgesic effect and reduced constipation	-
[翁紹華] 期刊論文	2022-02-05	Discovery and development of a novel N-(3-bromophenyl)-{[(phenylcarbamoyl)amino]methyl}-N-hydroxythiophene-2-carboximidamide indoleamine 2,3-dioxygenase inhibitor using knowledge-based drug design	-
[翁紹華] 期刊論文	2018-04	4-Bromophenylhydrazinyl benzenesulfonylphenylureas as indoleamine 2,3-dioxygenase inhibitors with in vivo target inhibition and anti-tumor efficacy	-
[翁紹華] 期刊論文	2017-05	1-(2,4-Dibromophenyl)-3,6,6-trimethyl-1,5,6,7-tetrahydro-4H-indazol-4-one: A novel opioid receptor agonist with less accompanying gastrointestinal dysfunction than morphine	-
[翁紹華] 期刊論文	2017-01	Discovery, structure-activity relationship studies, and anti-nociceptive effects of N-(1,2,3,4-tetrahydro-1-isoquinolinylmethyl)benzamides as novel opioid receptor agonists	-
[翁紹華] 期刊論文	2016-01	Phenyl benzenesulfonylhydrazides exhibit selective Indoleamine 2,3-Dioxygenase inhibition with potent in vivo pharmacodynamic activity and antitumor efficacy	-
[葉修華] 期刊論文	2024-10-29	DBPR116, a prodrug of BPRMU191, in combination with naltrexone as a safer opioid analgesic than morphine via peripheral administration	-
[葉修華] 期刊論文	2024-07-17	Discovery of a mu-opioid receptor modulator that in combination with morphinan antagonists induces analgesia	-
[葉修華] 期刊論文	2023-10-05	A dual nociceptin and mu opioid receptor agonist exhibited robust antinociceptive effect with decreased side effects	-
[葉修華] 期刊論文	2020-04	BPR1M97, a dual mu opioid receptor/nociceptin-orphanin FQ peptide receptor agonist, produces potent antinociceptive effects with safer properties than morphine	-
[葉燈光] 專利	2014-08-15	Anticancer oral formulation	-
[葉燈光] 專利	2014-06-04	抗癌口服制剂	-
[葉燈光] 專利	2013-06-05	Anticancer oral formulation	-
[葉燈光] 專利	2013-02-11	抗癌口服藥學組成物	-
[葉燈光] 專利	2011-09-27	Formulations of indol-3-yl-2-oxoacetamide compounds	-
[葉燈光] 會議論文/會議摘要	2019-10	Discovery of clinical candidate DBPR112, a furanopyrimidine-based epidermal growth factor receptor inhibitor for the treatment of non-small cell lung cancer	-
[葉燈光] 會議論文/會議摘要	2017-04	Discovery of BPR1K871-a quinazoline based multi-kinase inhibitor for the treatment of AML and solid tumors: Rational design, synthesis, in vitro and in vivo evaluation	-
[葉燈光] 會議論文/會議摘要	2013-11	A development drug candidate targeting EGFR kinase for lung cancer: DBPR112	-
[葉燈光] 期刊論文	2022-12-05	2,6-Difluorobenzamide derivatives as store-operated calcium channel (SOC) inhibitors	-
[葉燈光] 期刊論文	2020-02-01	Protective effects of 10,11-dihydro-5H-dibenzo[b,f]azepine hydroxamates on vascular cognitive impairment	-
[葉燈光] 期刊論文	2019-06-05	Delta-opioid receptor antagonist naltrindole reduces oxycodone addiction and constipation in mice	-
[葉燈光] 期刊論文	2019-05	Synthesis and evaluation of novel 7H-pyrrolo-[2,3-d]pyrimidine derivatives as potential anticancer agents	-
[葉燈光] 期刊論文	2018-08-23	5-aroylindoles act as selective histone deacetylase 6 inhibitors ameliorating alzheimer's disease phenotypes	-
[葉燈光] 期刊論文	2016-09	Activation of delta-opioid receptor contributes to the antinociceptive effect of oxycodone in mice	-
[葉燈光] 期刊論文	2016-07	In vitro and in vivo studies of a potent capsid-binding inhibitor of enterovirus 71	-
[葉燈光] 期刊論文	2015-01	1-Arylsulfonyl-5-(N-hydroxyacrylamide)tetrahydroquinolines as potent histone deacetylase inhibitors suppressing the growth of prostate cancer cells	-
[葉燈光] 期刊論文	2013-11	BPR0C305, an orally active microtubule-disrupting anticancer agent	-
[葉燈光] 期刊論文	2013-07-08	1-arylsulfonyl-5-(N-hydroxyacrylamide)indolines histone deacetylase inhibitors are potent cytokine release suppressors	-
[葉燈光] 期刊論文	2013-07-08	Inside Cover: 1-arylsulfonyl-5-(N-hydroxyacrylamide)indolines histone deacetylase inhibitors are potent cytokine release suppressors(ChemBioChem 10/2013)	-
[葉燈光] 期刊論文	2012-12-13	Synthesis and biological evaluation of tylophorine-derived dibenzoquinolines as orally active agents: Exploration of the role of tylophorine e ring on biological activity	-
[葉燈光] 期刊論文	2012-06	Effects of Bu-Zhong-Yi-Qi-Tang on hepatic drug-metabolizing enzymes and plasma tolbutamide concentration in rats	-
[葉燈光] 期刊論文	2012-04	Synthesis and biological evaluation of 1-Arylsulfonyl-5-(N-hydroxyacrylamide)indoles as potent histone deacetylase inhibitors with antitumor activity in vivo	-
[葉燈光] 期刊論文	2012-02-01	Kinetics and tissue distribution of neutron-activated zinc oxide nanoparticles and zinc nitrate in mice: Effects of size and particulate nature	-
[葉燈光] 期刊論文	2011-03	Effect of shengmai san on insulin resistance, tumor necrosis factor-alpha and oxidative stress in rats fed on a high-fat diet	-
[葉燈光] 期刊論文	2009-07	Effect of taurine supplementation on cytochrome P450 2E1 and oxidative stress in the liver and kidneys of rats with streptozotocin-induced diabetes	-
[葉燈光] 期刊論文	2008-07	Computational and ultrastructural toxicology of a nanoparticle, Quantum Dot 705, in mice	-
[葉燈光] 期刊論文	2008-05	High-performance liquid chromatography-electrospray mass spectrometry for the simultaneous determination of multiple active components in Sheng-Mai San, a prescription of traditional Chinese medicine	-
[葉燈光] 期刊論文	2008-02-28	Shengmai San reduces hepatic lipids and lipid peroxidation in rats fed on a high-cholesterol diet	-
[葉燈光] 期刊論文	2008-02	The inhibitory effect of tannic acid on cytochrome P450 enzymes and NADPH-CYP reductase in rat and human liver microsomes	-
[葉燈光] 期刊論文	2007-10-01	Rapid and sensitive determination of fentanyl in dog plasma by on-line solid-phase extraction integrated with a hydrophilic column coupled to tandem mass spectrometry	-
[葉燈光] 期刊論文	2007-09-15	Quantitative determination of salidroside in rat plasma by on-line solid-phase extraction integrated with high-performance liquid chromatography/electrospray ionization tandem mass spectrometry	-
[葉燈光] 期刊論文	2007-07	Biotransformation of 6-methoxy-3-(3 ',4 ',5 '-trimethoxy-benzoyl)-1-hindole (BPR0L075), a novel antimicrotubule agent, by mouse, rat, dog, and human liver microsomes	-
[葉燈光] 期刊論文	2006-11-25	The inhibitory effect of polyunsaturated fatty acids on human CYP enzymes	-
[蔣維棠] 期刊論文	2021-01	Potent and orally active purine-based fetal hemoglobin inducers for treating Beta-thalassemia and sickle cell disease	-
[蔣維棠] 期刊論文	2019-12	Identification of a multitargeted tyrosine kinase inhibitor for the treatment of gastrointestinal stromal tumors and acute myeloid leukemia	-
[蔣維棠] 期刊論文	2015-07	Identification of a potent 5-phenyl-thiazol-2-ylamine-based inhibitor of FLT3 with activity against drug resistance-conferring point mutations	-
[蔣維棠] 期刊論文	2013-06	Discovery of 3-phenyl-1H-5-pyrazolylamine derivatives containing a urea pharmacophore as potent and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3)	-
[蔣維棠] 期刊論文	2012-06-07	3-Phenyl-1H-5-pyrazolylamine-based derivatives as potent and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3)	-
[蔣維棠] 期刊論文	2011-07	Discovery and evaluation of 3-phenyl-1H-5-pyrazolylamine-based derivatives as potent, selective and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3)	-
[蔣維棠] 期刊論文	2009-04-01	Rational design and synthesis of potent and long-lasting glutamic acid-based dipeptidyl peptidase IV inhibitors	-
[蔣維棠] 期刊論文	2009-03-15	Novel trans-2-aryl-cyclopropylamine analogues as potent and selective dipeptidyl peptidase IV inhibitors	-
[謝興邦] 會議論文/會議摘要	2023-10	Discovery of novel AXL and MER inhibitors as potential anticancer and immune modulator drugs	-
[謝興邦] 會議論文/會議摘要	2014-11	Discovery of multiple kinases inhibitors, DBPR114, as the novel anti-cancer agent	-
[謝興邦] 會議論文/會議摘要	2014-10	Novel irreversible EGFR tyrosine kinase inhibitor, DBPR112, as a therapeutic candidate for lung adenocarcinoma	-
[謝興邦] 會議論文/會議摘要	2013-04-07	BPR000K, a novel Aurora kinase inhibitor	-
[謝興邦] 會議論文/會議摘要	2013-04-07	3D-QSAR assisted drug design: Identification of a potent quinazoline based Aurora kinase inhibitor	-
[謝興邦] 會議論文/會議摘要	2013-04-07	Development drug candidate targeting EGFR kinase: DBPR112	-
[謝興邦] 會議論文/會議摘要	2011-03-27	Design and synthesis of potent Aurora kinase inhibitors	-
[謝興邦] 期刊論文	2024-06-24	Discovery of dual MER/AXL kinase inhibitors as bifunctional small molecules for inhibiting tumor growth and enhancing tumor immune microenvironment	-
[謝興邦] 期刊論文	2023-02-07	Development of furanopyrimidine-based orally active third-generation EGFR inhibitors for the treatment of non-small cell lung cancer	-
[謝興邦] 期刊論文	2021-11-15	Design and synthesis of novel orally selective and type II pan-TRK inhibitors to overcome mutations by property-driven optimization	-
[謝興邦] 期刊論文	2021-10-14	Discovery of BPR1R024, an orally active and selective CSF1R inhibitor that exhibits antitumor and immunomodulatory activity in a murine colon tumor model	-
[謝興邦] 期刊論文	2021-01	Overcoming vincristine resistance in cancer: Computational design and discovery of piperine-inspired P-glycoprotein inhibitors	-
[謝興邦] 期刊論文	2020-05	Drug-like property optimization: Discovery of orally bioavailable quinazoline-based multi-targeted kinase inhibitors	-
[謝興邦] 期刊論文	2019-11-27	Discovery of a furanopyrimidine-based epidermal growth factor receptor inhibitor (DBPR112) as a clinical candidate for the treatment of non-small cell lung cancer	-
[謝興邦] 期刊論文	2017-08-11	Targeting P-glycoprotein: Investigation of piperine analogs for overcoming drug resistance in cancer	-
[謝興邦] 期刊論文	2016-12	Discovery of BPR1K871, a quinazoline based, multi-kinase inhibitor for the treatment of AML and solid tumors: Rational design, synthesis, in vitro and in vivo evaluation	-
[謝興邦] 期刊論文	2013-01	3D-QSAR-assisted drug design: Identification of a potent quinazoline-based aurora kinase inhibitor	-
[謝興邦] 期刊論文	2012-09	Anti-influenza drug discovery: Identification of an orally bioavailable quinoline derivative through activity- and property-guided lead optimization	-
[謝興邦] 期刊論文	2011-04-28	Scaffold-hopping strategy: Synthesis and biological evaluation of 5,6-Fused bicyclic heteroaromatics to identify orally bioavailable anticancer agents	-
[謝興邦] 期刊論文	2009-08-13	Synthesis and evaluation of 3-aroylindoles as anticancer agents: Metabolite approach	-
[謝興邦] 期刊論文	2007-02-01	Development and validation of a liquid chromatography-tandem mass spectrometry for the determination of BPR0L075, a novel antimicrotuble agent, in rat plasma: Application to a pharmacokinetic study	-
[謝興邦] 期刊論文	2006-10	Structure-activity relationship studies of 3-aroylindoles as potent antimitotic agents	-
[趙宇生(2002-2013)] 會議論文/會議摘要	2012-11	BPR1J271, a novel FLT3 inhibitor for treating acute myeloid leukemia	-
[趙宇生(2002-2013)] 期刊論文	2011-01-13	Discovery of novel N -Beta- d -Xylosylindole derivatives as sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors for the management of hyperglycemia in diabetes	-
[趙宇生(2002-2013)] 期刊論文	2010-11	Identification of phenanthroindolizines and phenanthroquinolizidines as novel potent anti-coronaviral agents for porcine enteropathogenic coronavirus transmissible gastroenteritis virus and human severe acute respiratory syndrome coronavirus	-
[趙宇生(2002-2013)] 期刊論文	2010-10-28	Design and synthesis of tetrahydropyridothieno[2,3-d]pyrimidine scaffold based epidermal growth factor receptor (EGFR) kinase inhibitors: the role of side chain chirality and michael acceptor group for maximal potency	-
[趙宇生(2002-2013)] 期刊論文	2010-09-01	Synthesis, activity, and pharmacokinetic properties of a series of conformationally-restricted thiourea analogs as novel hepatitis C virus inhibitors	-
[趙宇生(2002-2013)] 期刊論文	2010-08	Substituted 4-carboxymethylpyroglutamic acid diamides as potent and selective inhibitors of fibroblast activation protein	-
[趙宇生(2002-2013)] 期刊論文	2010-07	Antiangiogenic Activities and Cisplatin-combined Antitumor Activities of BPR0L075	-
[郭靜娟] 期刊論文	2015-08	Novel Nrf2/ARE activator, trans-coniferylaldehyde, induces a HO-1-mediated defense mechanism through a dual p38alpha/MAPKAPK-2 and PK-N3 signaling pathway	-
[鄒倫] 期刊論文	2022-07	Rejuvenating hepatic tumor microenvironment immunity with a phosphatidylserine-targeting small molecule drug conjugate	-
[鄒倫] 期刊論文	2022-06-21	Synthesis and evaluation of small molecule drug conjugates harnessing thioester-linked maytansinoids	-
[鄒倫] 期刊論文	2022-02-15	Click chemistry and multicomponent reaction for linker diversification of zinc dipicolylamine-based drug conjugates	-
[鄒倫] 期刊論文	2021-01	BPRDP056, a novel small molecule drug conjugate specifically targeting phosphatidylserine for cancer therapy	-
[鄒倫] 期刊論文	2019-07-11	Linker optimization and therapeutic evaluation of phosphatidylserine-targeting zinc dipicolylamine-based drug conjugates	-
[鄒倫] 期刊論文	2017-07	Targeting tumor associated phosphatidylserine with new zinc dipicolylamine-based drug conjugates	-
[鄒小蕙] 期刊論文	2013-07	CYP1A2 genetic polymorphisms are associated with early antidepressant escitalopram metabolism and adverse reactions	-
[陳志豪] 期刊論文	2019-04-01	A novel, potent, and orally bioavailable thiazole HCV NS5A inhibitor for the treatment of hepatitis C virus	-
[陳志豪] 期刊論文	2017-01	A potent, selective, and orally bioavailable HCV NS5A inhibitor for treatment of Hepatitis C Virus: (S)-1-((R)-2-(Cyclopropanecarboxamido)-2-phenylacetyl)-N-(4-phenylthiazo l-2-yl)pyrrolidine-2-carboxamide	-
[陳新(2002-2015)] 期刊論文	2010-06-15	(2S,4S)-1-[2-(1,1-Dimethyl-3-oxo-3-pyrrolidin-1-yl-propylamino)acetyl]-4-fluoro-pyrrolidine-2-carbonitrile: A potent, selective, and orally bioavailable dipeptide-derived inhibitor of dipeptidyl peptidase IV	-
[陳新(2002-2015)] 期刊論文	2009-07-15	Biochemistry, pharmacokinetics, and toxicology of a potent and selective DPP8/9 inhibitor	-
[陳炯東] 會議論文/會議摘要	2019-07	BPRDP056, a novel small molecule drug conjugate specifically targeting phosphatidylserine for cancer therapy	-
[陳炯東] 會議論文/會議摘要	2018-01	Discovery and development of DBPR112 as a clinical candidate: A novel EGFR inhibitor for non-small cell lung cancer	-
[陳炯東] 會議論文/會議摘要	2016-12	Novel cKIT kinase inhibitor, BPRCKJ001, as an advanced therapeutic candidate for GIST	-
[陳炯東] 會議論文/會議摘要	2015-08	Zinc-dipicolylamine directed pharmaceutical delivery system (ZAPS) as an innovative cancer drug delivery platform	-
[陳炯東] 會議論文/會議摘要	2015-08	Optimization of quinazoline-based kinase inhibitors: Identification of a dual FLT3/AURKA kinase inhibitor for the treatment of acute myeloid leukemia	-
[陳炯東] 期刊論文	2022-10-13	Targeting the phosphatidylserine-immune checkpoint with a small-molecule maytansinoid conjugate	-
[陳炯東] 期刊論文	2021-08-01	DBPR108, a novel dipeptidyl peptidase-4 inhibitor with antihyperglycemic activity	-
[陳炯東] 期刊論文	2020-08	Artificial intelligence approach fighting COVID-19 with repurposing drugs	-
[陳炯東] 期刊論文	2011-01	BPR0C261 is a novel orally active antitumor agent with antimitotic and anti-angiogenic activities	-
[陳炯東] 期刊論文	2010-02	Antitumor activities and pharmacokinetics of silatecans DB-67 and DB-91	-
[陳炯東] 期刊論文	2008-07-09	Enhanced oral bioavailability of paclitaxel by D-alpha-tocopheryl polyethylene glycol 400 succinate in mice	-
[陳炯東] 期刊論文	2006-12	Pharmacokinetics of anti-SARS-CoV agent niclosamide and its analogs in rats	-
[黃智興] 期刊論文	2024-07-04	Development of a humanized antibody targeting extracellular HSP90alpha to suppress endothelial-mesenchymal transition-enhanced tumor growth of pancreatic adenocarcinoma cells	-

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