國家衛生研究院 NHRI:
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    近3年内发表的文件:6(8.57%)
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    显示项目1-50 / 70. (共2页)
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    日期题名關聯
    2024-01-14 Benzimidazole compounds and use thereof for treating alzheimer's disease or huntington's disease SG11202101274X/2024-01-14
    2023-06-01 增加細胞吞噬作用之方法 TWI804339/2023-06-01
    2023-03-03 Benzimidazole compounds and use thereof for treating alzheimer's disease or huntington's disease IN424040/2023-03-03
    2023-01-27 苯並咪唑化合物及其在製備治療阿茲海默症或亨丁頓氏症的藥物中的用途 HK40053325/2023-01-27
    2023-01-26 苯并咪唑化合物及其在製備治療阿茲海默症或亨丁頓氏症的藥物中的用途 J/006659/2023-01-26
    2023-01-24 Benzimidazole compounds and use thereof for treating alzheimer's disease or huntington's disease CA3109623/2023-01-24
    2022-08-23 苯并咪唑化合物及其在制备治疗阿兹海默症或亨丁顿氏症的药物中的用途 CN113613652/2022-08-23
    2022-08 Rosmarinic acid interferes with influenza virus A entry and replication by decreasing GSK3beta and phosphorylated AKT expression levels Journal of Microbiology, Immunology, and Infection. 2022 Aug;55(4):598-610.
    2022-05-31 벤즈이미다졸 화합물 및 알츠하이머 질환 또는 헌팅톤병을 치료하기 위한 그의 용도 KR 10-2405760/2022-05-31
    2022-03-14 ベンズイミダゾール化合物,及びアルツハイマー病又はハンチントン病の治療のためのその使用 JP7035275/2022-03-14
    2021-11-11 Benzimidazole compounds and use thereof for treating alzheimer's disease or huntington's disease AU2019333295/2021-11-11
    2021-01-01 苯并咪唑化合物及其用於治療阿茲海默症或亨丁頓氏症之用途 TWI715156/2021-01-01
    2020-12 Rosmarinic acid exhibits broad anti-enterovirus A71 activity by inhibiting the interaction between the five-fold axis of capsid VP1 and cognate sulfated receptors Emerging Microbes and Infections. 2020 Dec;9(1):1194-1205.
    2020-03-10 Benzimidazole compounds and use thereof for treating alzheimer's disease or huntington's disease US10584120/2020-03-10
    2019-12 A novel flavivirus entry inhibitor, BP34610, discovered through high-throughput screening with dengue reporter viruses Antiviral Research. 2019 Dec;172:Article number 104636.
    2019-04-01 A novel, potent, and orally bioavailable thiazole HCV NS5A inhibitor for the treatment of hepatitis C virus European Journal of Medicinal Chemistry. 2019 Apr 1;167:245-268.
    2019-03-20 Proline derivatives EP2507232/2019-03-20
    2018-09 Development of robust genotype 1a hepatitis C replicons harboring adaptive mutations for facilitating the antiviral drug discovery and study of virus replication Journal of Virological Methods. 2018 Sep;259:10-17.
    2017-12 Stimulatory actions of a novel thiourea derivative on large-conductance, calcium-activated potassium channels Journal of Cellular Physiology. 2017 Dec;232(12):3409-3421.
    2017-10-24 Proline derivatives for use to treat hepatitis c infection CA2781140/2017-10-24
    2017-08-10 프롤린 유도체 KR10-1768946/2017-08-10
    2017-06 Mutagenesis of dengue virus protein NS2A revealed a novel domain responsible for virus-induced cytopathic effect and interactions between NS2A and NS2B transmembrane segments Journal of Virology. 2017 Jun;91(12):Article number e01836-16.
    2017-01 A potent, selective, and orally bioavailable HCV NS5A inhibitor for treatment of Hepatitis C Virus: (S)-1-((R)-2-(Cyclopropanecarboxamido)-2-phenylacetyl)-N-(4-phenylthiazo l-2-yl)pyrrolidine-2-carboxamide Journal of Medicinal Chemistry. 2017 Jan;60(1):228-247.
    2016-07-21 Proline derivatives AU2010325980/2016-07-21
    2016-07 In vitro and in vivo studies of a potent capsid-binding inhibitor of enterovirus 71 Journal of Antimicrobial Chemotherapy. 2016 Jul;71(7):1922-1932.
    2016-06-17 脯氨酸衍生物 HK1171439/2016-06-17
    2016-02-04 脯氨酸衍生物 J/001913/2016-02-04
    2015-07-29 脯氨酸衍生物 CN102482269/2015-07-29
    2015-05-29 Proline derivatives JP5753185/2015-05-29
    2014-09-01 治療阿茲海默症或帕金森氏症之醫藥組成物 TWI450716/2014-09-01
    2014-03-11 脯胺酸衍生物 TWI429645/2014-03-11
    2014-01 A novel dengue virus inhibitor, BP13944, discovered by high-throughput screening with dengue virus replicon cells selects for resistance in the viral NS2B/NS3 protease Antimicrobial Agents and Chemotherapy. 2014 Jan;58(1):110-119.
    2013-04-09 Proline derivatives US8415482/2013-04-09
    2013-02 Resistance studies of a di-thiazol analogue, DBPR110, as a potential hepatitis C virus NS5A inhibitor in replicon systems Antimicrobial Agents and Chemotherapy. 2013 Feb; 57(2):723-733.
    2012-06-12 Treatment of neurodegenerative disorders with thiourea compounds US8198284/2012-06-12
    2012-04-11 咪唑啉酮及咪唑啉硫酮衍生物 TWI361808/2012-04-11
    2012-03-01 C型肝炎病毒抑制劑 TWI359137/2012-03-01
    2012-01 Resistance analysis and characterization of a thiazole analogue, BP008, as a potent hepatitis C virus NS5A inhibitor Antimicrobial Agents and Chemotherapy. 2012 Jan;56(1):44-53.
    2011-07-26 Hepatitis C virus inhibitors US7985763/2011-07-26
    2011-05-10 Imidazolidinone and imidazolidinethione derivatives US7939523/2011-05-10
    2011-04 Antitumor effect of BPR-DC-2, a novel synthetic cyclic cyanoguanidine derivative, involving the inhibition of MDR-1 expression and down-regulation of p-AKT and PARP-1 in lung cancer Investigational New Drugs. 2011 Apr;29(2):195-206.
    2011-04 Isatin-beta-thiosemicarbazones as potent herpes simplex virus inhibitors Bioorganic and Medicinal Chemistry Letters. 2011 Apr;21(7):1948-1952.
    2011-03-01 Thiourea derivatives US7897764/2011-03-01
    2011-01 Novel dengue virus-specific NS2B/NS3 protease inhibitor, BP2109, discovered by a high-throughput screening assay Antimicrobial Agents and Chemotherapy. 2011 Jan;55(1):229-238.
    2011-01 BPR0C261 is a novel orally active antitumor agent with antimitotic and anti-angiogenic activities Cancer Science. 2011 Jan;102(1):182-191.
    2010-10 Modulation of microglial immune responses by a novel thiourea derivative Chemico-Biological Interactions. 2010 Oct;188(1):228-236.
    2010-09-01 Synthesis, activity, and pharmacokinetic properties of a series of conformationally-restricted thiourea analogs as novel hepatitis C virus inhibitors Bioorganic and Medicinal Chemistry. 2010 Sep ;18(17):6414-6421.
    2010-08-21 硫尿化合物及抑制C型肝炎病毒感染之方法 TWI329102/2010-08-21
    2010-05-11 咪唑啉酮化合物 TWI324594/2010-05-11
    2009-11-01 Design and efficient synthesis of novel arylthiourea derivatives as potent hepatitis C virus inhibitors Bioorganic and Medicinal Chemistry Letters. 2009 Nov 1;19(21):6063-6068.

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