國家衛生研究院 NHRI:
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    显示项目26-50 / 66. (共3页)
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    日期题名關聯
    2013-04-30 Pyrrolidine derivatives 164613/2013-04-30
    2013-02-11 吡咯啉啶化合物 I385163/2013-02-11
    2013-02-11 吡咯啶化合物 I385171/2013-02-11
    2013-02 Resistance studies of a di-thiazol analogue, DBPR110, as a potential hepatitis C virus NS5A inhibitor in replicon systems Antimicrobial Agents and Chemotherapy. 2013 Feb; 57(2):723-733.
    2012-11 BPR1J271, a novel FLT3 inhibitor for treating acute myeloid leukemia European Journal of Cancer. 2012 Nov;48(Suppl. 6):53-54.
    2012-06-15 Pyrrolidine derivatives 587911/2012-06-15
    2012-06-07 3-Phenyl-1H-5-pyrazolylamine-based derivatives as potent and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3) Bioorganic and Medicinal Chemistry Letters. 2012 Jun 7;22(14):4654-4659.
    2012-04-21 吡咯啉啶化合物 I362388/2012-04-21
    2012-01-17 Pyrrolidine compounds CA2559611/2012-01-17
    2012-01 Resistance analysis and characterization of a thiazole analogue, BP008, as a potent hepatitis C virus NS5A inhibitor Antimicrobial Agents and Chemotherapy. 2012 Jan;56(1):44-53.
    2012-01 BPR1J-097, a novel FLT3 kinase inhibitor, exerts potent inhibitory activity against AML British Journal of Cancer. 2012 Jan;106(3):475-481.
    2011-12-06 Pyrrolidine compounds US8071787B2/2011-12-06
    2011-09-20 Pyrrolidine derivatives US8022096B2/2011-09-20.
    2011-07 Discovery and evaluation of 3-phenyl-1H-5-pyrazolylamine-based derivatives as potent, selective and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3) Bioorganic and Medicinal Chemistry. 2011 Jul;19(14):4173-4182 .
    2011-06 Cleavage-site specificity of prolyl endopeptidase FAP investigated with a full-length protein substrate Journal of Biochemistry. 2011 Jun;149(6):685-692.
    2011-06 Current advances and therapeutic potential of agents targeting dipeptidyl peptidases-IV, -II, 8/9 and fibroblast activation protein Current Topics In Medicinal Chemistry. 2011 Jun;(11):1447-1463.
    2011-05-25 Pyrrolidine derivatives ZA201006329B/2011-05-25
    2011-02 Synthesis of 3,3-dimethylglutamic acid derivatives as DPP-IV inhibitors and evaluation of their chemical stability Journal of the Chinese Chemical Society. 2011 Feb;58(1):108-117.
    2010-10-06 吡咯烷化合物 ZL200580009891.6/2010-10-06
    2010-09 The dimeric transmembrane domain of prolyl dipeptidase DPP-IV contributes to its quaternary structure and enzymatic activities Protein Science. 2010 Sep;19(9):1627-1638.
    2010-08 Substituted 4-carboxymethylpyroglutamic acid diamides as potent and selective inhibitors of fibroblast activation protein Journal of Medicinal Chemistry. 2010 Aug;53(18):6572-6583.
    2010-06-15 (2S,4S)-1-[2-(1,1-Dimethyl-3-oxo-3-pyrrolidin-1-yl-propylamino)acetyl]-4-fluoro-pyrrolidine-2-carbonitrile: A potent, selective, and orally bioavailable dipeptide-derived inhibitor of dipeptidyl peptidase IV Bioorganic and Medicinal Chemistry Letters. 2010 Jun 15;20(12):3596-3600.
    2010-03-30 Pyrrolidine compounds US7687504B2/2010-03-30
    2009-10 (1,3-Diphenyl-1H-pyrazol-4-yl)-methylamine analogues as inhibitors of dipeptidyl peptidases Journal of the Chinese Chemical Society. 2009 Oct;56(5):1048-1055.
    2009-07-15 Biochemistry, pharmacokinetics, and toxicology of a potent and selective DPP8/9 inhibitor Biochemical Pharmacology. 2009 Jul 15;78(2):203-210.

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