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Probing for improved selectivity wi...
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顯示項目51-67 / 67. (共3頁)
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2006-06-15
Substituted pyrrolidine-2,4-dicarboxylic acid amides as potent dipeptidyl peptidase IV inhibitors
Bioorganic and Medicinal Chemistry Letters. 2006 Jun;16(12):3268-3272.
2006-06-13
Identification of hydrophobic residues critical for DPP-IV dimerization
Biochemistry. 2006 Jun;45(23):7006-7012.
2006-05-04
Structure-based drug design of a novel family of PPAR gamma partial agonists: Virtual screening, X-ray crystallography, and in vitro/in vivo biological activities
Journal of Medicinal Chemistry. 2006 May;49(9):2703-2712.
2006-04
Chromatin-binding in vivo of the erythroid kruppel-like factor, EKLF, in the murine globin loci
Cell Research. 2006 Apr;16(4):347-355.
2006-02-09
Indol-1-yl acetic acids as peroxisome proliferator-activated receptor agonists: Design, synthesis, structural biology, and molecular docking studies
Journal of Medicinal Chemistry. 2006 Feb;49(3):1212-1216.
2006-01-12
2-[3-[2-[(2S)-2-cyano-1-pyrrolidinyl]-2-oxoethylamino]-3-methyl-1-oxobutyl]-1,2,3,4-tetrahydroisoquinoline: A potent, selective, and orally bioavailable dipeptide-derived inhibitor of dipeptidyl peptidase IV
Journal of Medicinal Chemistry. 2006 Jan;49(1):373-380.
2005-12-29
Novel indole-based peroxisome proliferator-activated receptor agonists: Design, SAR, structural biology, and biological activities
Journal of Medicinal Chemistry. 2005 Dec;48(26):8194-8208.
2005-08-02
Papain-like protease 2 (PLP2) from severe acute respiratory syndrome coronavirus (SARS-CoV): Expression, purification, characterization, and inhibition
Biochemistry. 2005 Aug;44(30):10349-10359.
2005-07-01
Inhibition of dipeptidyl-peptidase IV catalyzed peptide truncation by vildagliptin ((2S)-{[3-hydroxyadamantan-1-yl) amino]acetyl}-pyrrolidine-2-carbonitrile)
Biochemical Pharmacology. 2005 Jul;70(1):134-143.
2005-07-01
Glutamic acid analogues as potent dipeptidyl peptidase IV and 8 inhibitors
Bioorganic and Medicinal Chemistry Letters. 2005 Jul;15(13):3271-3275.
2005-03
Design, synthesis and sar of indole-based PPAR agonists
Abstracts of Papers of the American Chemical Society. 2005 Mar;229(Part 2):U141.
2005-03
Design and structure-activity relationships of novel indole-based PPAR agonists as antidiabetic agents
Abstracts of Papers of the American Chemical Society. 2005 Mar;229(Part 2):U141.
2005-02-01
Novel isoindoline compounds for potent and selective inhibition of prolyl dipeptidase DPP8
Bioorganic and Medicinal Chemistry Letters. 2005 Feb;15(3):687-691.
2004-12-10
One site mutation disrupts dimer formation in human DPP-IV proteins
Journal of Biological Chemistry. 2004 Dec;279(50):52338-52345.
2004-09-10
Evaluation of metal-conjugated compounds as inhibitors of 3CL protease of SARS-CoV
FEBS Letters. 2004 Sep;574(1-3):116-120.
2004-05
Purification and characterization of human prolyl dipeptidase DPPS in Sf9 insect cells
Protein Expression and Purification. 2004 May;35(1):142-146.
2003-01
Congenital dyserythropoietic anemia type II: exclusion of seven candidate genes
Blood Cells Molecules and Diseases. 2003 Jan-Feb;30(1):22-29.
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