國家衛生研究院 NHRI:
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    Patents [0/11]
    Periodical Articles [52/52]
    Conference Papers/Meeting Abstract [1/4]

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    Showing items 51-67 of 67. (3 Page(s) Totally)
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    DateTitleRelation
    2006-06-15 Substituted pyrrolidine-2,4-dicarboxylic acid amides as potent dipeptidyl peptidase IV inhibitors Bioorganic and Medicinal Chemistry Letters. 2006 Jun;16(12):3268-3272.
    2006-06-13 Identification of hydrophobic residues critical for DPP-IV dimerization Biochemistry. 2006 Jun;45(23):7006-7012.
    2006-05-04 Structure-based drug design of a novel family of PPAR gamma partial agonists: Virtual screening, X-ray crystallography, and in vitro/in vivo biological activities Journal of Medicinal Chemistry. 2006 May;49(9):2703-2712.
    2006-04 Chromatin-binding in vivo of the erythroid kruppel-like factor, EKLF, in the murine globin loci Cell Research. 2006 Apr;16(4):347-355.
    2006-02-09 Indol-1-yl acetic acids as peroxisome proliferator-activated receptor agonists: Design, synthesis, structural biology, and molecular docking studies Journal of Medicinal Chemistry. 2006 Feb;49(3):1212-1216.
    2006-01-12 2-[3-[2-[(2S)-2-cyano-1-pyrrolidinyl]-2-oxoethylamino]-3-methyl-1-oxobutyl]-1,2,3,4-tetrahydroisoquinoline: A potent, selective, and orally bioavailable dipeptide-derived inhibitor of dipeptidyl peptidase IV Journal of Medicinal Chemistry. 2006 Jan;49(1):373-380.
    2005-12-29 Novel indole-based peroxisome proliferator-activated receptor agonists: Design, SAR, structural biology, and biological activities Journal of Medicinal Chemistry. 2005 Dec;48(26):8194-8208.
    2005-08-02 Papain-like protease 2 (PLP2) from severe acute respiratory syndrome coronavirus (SARS-CoV): Expression, purification, characterization, and inhibition Biochemistry. 2005 Aug;44(30):10349-10359.
    2005-07-01 Inhibition of dipeptidyl-peptidase IV catalyzed peptide truncation by vildagliptin ((2S)-{[3-hydroxyadamantan-1-yl) amino]acetyl}-pyrrolidine-2-carbonitrile) Biochemical Pharmacology. 2005 Jul;70(1):134-143.
    2005-07-01 Glutamic acid analogues as potent dipeptidyl peptidase IV and 8 inhibitors Bioorganic and Medicinal Chemistry Letters. 2005 Jul;15(13):3271-3275.
    2005-03 Design, synthesis and sar of indole-based PPAR agonists Abstracts of Papers of the American Chemical Society. 2005 Mar;229(Part 2):U141.
    2005-03 Design and structure-activity relationships of novel indole-based PPAR agonists as antidiabetic agents Abstracts of Papers of the American Chemical Society. 2005 Mar;229(Part 2):U141.
    2005-02-01 Novel isoindoline compounds for potent and selective inhibition of prolyl dipeptidase DPP8 Bioorganic and Medicinal Chemistry Letters. 2005 Feb;15(3):687-691.
    2004-12-10 One site mutation disrupts dimer formation in human DPP-IV proteins Journal of Biological Chemistry. 2004 Dec;279(50):52338-52345.
    2004-09-10 Evaluation of metal-conjugated compounds as inhibitors of 3CL protease of SARS-CoV FEBS Letters. 2004 Sep;574(1-3):116-120.
    2004-05 Purification and characterization of human prolyl dipeptidase DPPS in Sf9 insect cells Protein Expression and Purification. 2004 May;35(1):142-146.
    2003-01 Congenital dyserythropoietic anemia type II: exclusion of seven candidate genes Blood Cells Molecules and Diseases. 2003 Jan-Feb;30(1):22-29.

    Showing items 51-67 of 67. (3 Page(s) Totally)
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