國家衛生研究院 NHRI:
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    Collection

    Patents [0/32]
    Periodical Articles [143/144]
    Conference Papers/Meeting Abstract [27/39]

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    Showing items 26-50 of 215. (9 Page(s) Totally)
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    DateTitleRelation
    2019-04-01 A novel, potent, and orally bioavailable thiazole HCV NS5A inhibitor for the treatment of hepatitis C virus European Journal of Medicinal Chemistry. 2019 Apr 1;167:245-268.
    2019-02-20 Convallatoxin enhance the ligand-induced mu-opioid receptor endocytosis and attenuate morphine antinociceptive tolerance in mice Scientific Reports. 2019 Feb 20;9:Article number 2405.
    2018-12 Dendritic cell-derived exosomes increase the efficacy of anti-PD-L1 antibody in melanoma model Cancer Science. 2018 Dec;109(Suppl. 2):1322.
    2018-12 Targeting RSPO3 reduces stem cell function in RSPO3-Fusion-positive colon cancer and RSPO3 high lung cancer Cancer Science. 2018 Dec;109(SI, Suppl. 2):210.
    2018-12 Targeting RSPO3 reduces stem cell function in RSPO3-Fusion-positive colon cancer and RSPO3 high lung cancer Cancer Science. 2018 Dec;109(Suppl. 2, SI):1257.
    2018-10 Identification of novel Cdc7 kinase inhibitors as anti-cancer agents that target the interaction with Dbf4 by the fragment complementation and drug repositioning approach EBioMedicine. 2018 Oct;36:241-251.
    2018-08-24 BPR1J373, a novel multitargeted kinase inhibitor, effectively suppresses the growth of gastrointestinal stromal tumor Cancer Science. 2018 Nov;109(11):3591-3601.
    2018-07 Clinical candidate DBPR112: A novel epidermal growth factor receptor inhibitor as a promising treatment for non-small cell lung cancer Cancer Research. 2018 Jul;78(13, Suppl.):Meeting Abstract 4789.
    2018-01-23 Identification of danthron as an isoform-specific inhibitor of HEME OXYGENASE-1/cytochrome P450 reductase interaction with anti-tumor activity Journal of Biomedical Science. 2018 Jan 23;25:Article number 6.
    2018-01 Discovery and development of DBPR112 as a clinical candidate: A novel EGFR inhibitor for non-small cell lung cancer Cancer Science. 2018 Jan;109(Suppl. 1):739.
    2017-09-26 Identification of neuraminidase inhibitors against dual H274Y/I222R mutant strains Scientific Reports. 2017 Sep 26;7:Article number 12336.
    2017-07 Targeting tumor associated phosphatidylserine with new zinc dipicolylamine-based drug conjugates Bioconjugate Chemistry. 2017 Jul;28(7):1878-1892.
    2017-04 Discovery of BPR1K871-a quinazoline based multi-kinase inhibitor for the treatment of AML and solid tumors: Rational design, synthesis, in vitro and in vivo evaluation Abstracts of Papers of the American Chemical Society. 2017 Apr;253:Meeting Abstract 482.
    2017-01 A potent, selective, and orally bioavailable HCV NS5A inhibitor for treatment of Hepatitis C Virus: (S)-1-((R)-2-(Cyclopropanecarboxamido)-2-phenylacetyl)-N-(4-phenylthiazo l-2-yl)pyrrolidine-2-carboxamide Journal of Medicinal Chemistry. 2017 Jan;60(1):228-247.
    2016-12 Discovery of BPR1K871, a quinazoline based, multi-kinase inhibitor for the treatment of AML and solid tumors: Rational design, synthesis, in vitro and in vivo evaluation Oncotarget. 2016 Dec;7(52):86239-86256.
    2016-12 Glucocorticoids may compromise the effect of gefitinib in non-small cell lung cancer Oncotarget. 2016 Dec;7(52):85917-85928.
    2016-12 Novel cKIT kinase inhibitor, BPRCKJ001, as an advanced therapeutic candidate for GIST Annals of Oncology. 2016 Dec;27(Suppl. 9):Meeting Abstract 2P.
    2016-11-29 Discovery of novel inhibitors of Aurora kinases with indazole scaffold: In silico fragment-based and knowledge-based drug design European Journal of Medicinal Chemistry. 2016 Nov 29;124:186-199.
    2016-10 BPR1J373, an oral multiple tyrosine kinase inhibitor, targets c-KIT for the treatment of c-KIT driven myeloid leukemia Molecular Cancer Therapeutics. 2016 Oct;15(10):2323-2333.
    2016-09 Mycotoxin patulin suppresses innate immune responses by mitochondrial dysfunction and p62/sequestosome-1-dependent mitophagy Journal of Biological Chemistry. 2016 Sep;291(37):19299-19311.
    2016-07-28 Design and synthesis of 1,2,3-triazole-containing N-acyl zanamivir analogs as potent neuraminidase inhibitors European Journal of Medicinal Chemistry. 2016 Jul 28;123:397-406.
    2016-05-19 Non-small-cell lung cancer cells combat epidermal growth factor receptor tyrosine kinase inhibition through immediate adhesion-related responses OncoTargets and Therapy. 2016 May 19;9:2961-2973.
    2016-02-26 Using mutagenesis to explore conserved residues in the RNA-binding groove of influenza A virus nucleoprotein for antiviral drug development Scientific Reports. 2016 Feb 26;6:Article number 21662.
    2016-01-01 Bispecific antibody conjugated manganese-based magnetic engineered iron oxide for imaging of HER2/neu- and EGFR-expressing tumors Theranostics. 2016 Jan 1;6(1):118-130.
    2015-10 Identification of substituted naphthotriazolediones as novel tryptophan 2,3-dioxygenase (TDO) inhibitors through structure-based virtual screening Journal of Medicinal Chemistry. 2015 Oct;58 (19):7807-7819.

    Showing items 26-50 of 215. (9 Page(s) Totally)
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