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显示项目26-50 / 215. (共9页) << < 1 2 3 4 5 6 7 8 9 > >> 每页显示[10|25|50]项目

日期	题名	關聯
2019-04-01	A novel, potent, and orally bioavailable thiazole HCV NS5A inhibitor for the treatment of hepatitis C virus	European Journal of Medicinal Chemistry. 2019 Apr 1;167:245-268.
2019-02-20	Convallatoxin enhance the ligand-induced mu-opioid receptor endocytosis and attenuate morphine antinociceptive tolerance in mice	Scientific Reports. 2019 Feb 20;9:Article number 2405.
2018-12	Dendritic cell-derived exosomes increase the efficacy of anti-PD-L1 antibody in melanoma model	Cancer Science. 2018 Dec;109(Suppl. 2):1322.
2018-12	Targeting RSPO3 reduces stem cell function in RSPO3-Fusion-positive colon cancer and RSPO3 high lung cancer	Cancer Science. 2018 Dec;109(SI, Suppl. 2):210.
2018-12	Targeting RSPO3 reduces stem cell function in RSPO3-Fusion-positive colon cancer and RSPO3 high lung cancer	Cancer Science. 2018 Dec;109(Suppl. 2, SI):1257.
2018-10	Identification of novel Cdc7 kinase inhibitors as anti-cancer agents that target the interaction with Dbf4 by the fragment complementation and drug repositioning approach	EBioMedicine. 2018 Oct;36:241-251.
2018-08-24	BPR1J373, a novel multitargeted kinase inhibitor, effectively suppresses the growth of gastrointestinal stromal tumor	Cancer Science. 2018 Nov;109(11):3591-3601.
2018-07	Clinical candidate DBPR112: A novel epidermal growth factor receptor inhibitor as a promising treatment for non-small cell lung cancer	Cancer Research. 2018 Jul;78(13, Suppl.):Meeting Abstract 4789.
2018-01-23	Identification of danthron as an isoform-specific inhibitor of HEME OXYGENASE-1/cytochrome P450 reductase interaction with anti-tumor activity	Journal of Biomedical Science. 2018 Jan 23;25:Article number 6.
2018-01	Discovery and development of DBPR112 as a clinical candidate: A novel EGFR inhibitor for non-small cell lung cancer	Cancer Science. 2018 Jan;109(Suppl. 1):739.
2017-09-26	Identification of neuraminidase inhibitors against dual H274Y/I222R mutant strains	Scientific Reports. 2017 Sep 26;7:Article number 12336.
2017-07	Targeting tumor associated phosphatidylserine with new zinc dipicolylamine-based drug conjugates	Bioconjugate Chemistry. 2017 Jul;28(7):1878-1892.
2017-04	Discovery of BPR1K871-a quinazoline based multi-kinase inhibitor for the treatment of AML and solid tumors: Rational design, synthesis, in vitro and in vivo evaluation	Abstracts of Papers of the American Chemical Society. 2017 Apr;253:Meeting Abstract 482.
2017-01	A potent, selective, and orally bioavailable HCV NS5A inhibitor for treatment of Hepatitis C Virus: (S)-1-((R)-2-(Cyclopropanecarboxamido)-2-phenylacetyl)-N-(4-phenylthiazo l-2-yl)pyrrolidine-2-carboxamide	Journal of Medicinal Chemistry. 2017 Jan;60(1):228-247.
2016-12	Discovery of BPR1K871, a quinazoline based, multi-kinase inhibitor for the treatment of AML and solid tumors: Rational design, synthesis, in vitro and in vivo evaluation	Oncotarget. 2016 Dec;7(52):86239-86256.
2016-12	Glucocorticoids may compromise the effect of gefitinib in non-small cell lung cancer	Oncotarget. 2016 Dec;7(52):85917-85928.
2016-12	Novel cKIT kinase inhibitor, BPRCKJ001, as an advanced therapeutic candidate for GIST	Annals of Oncology. 2016 Dec;27(Suppl. 9):Meeting Abstract 2P.
2016-11-29	Discovery of novel inhibitors of Aurora kinases with indazole scaffold: In silico fragment-based and knowledge-based drug design	European Journal of Medicinal Chemistry. 2016 Nov 29;124:186-199.
2016-10	BPR1J373, an oral multiple tyrosine kinase inhibitor, targets c-KIT for the treatment of c-KIT driven myeloid leukemia	Molecular Cancer Therapeutics. 2016 Oct;15(10):2323-2333.
2016-09	Mycotoxin patulin suppresses innate immune responses by mitochondrial dysfunction and p62/sequestosome-1-dependent mitophagy	Journal of Biological Chemistry. 2016 Sep;291(37):19299-19311.
2016-07-28	Design and synthesis of 1,2,3-triazole-containing N-acyl zanamivir analogs as potent neuraminidase inhibitors	European Journal of Medicinal Chemistry. 2016 Jul 28;123:397-406.
2016-05-19	Non-small-cell lung cancer cells combat epidermal growth factor receptor tyrosine kinase inhibition through immediate adhesion-related responses	OncoTargets and Therapy. 2016 May 19;9:2961-2973.
2016-02-26	Using mutagenesis to explore conserved residues in the RNA-binding groove of influenza A virus nucleoprotein for antiviral drug development	Scientific Reports. 2016 Feb 26;6:Article number 21662.
2016-01-01	Bispecific antibody conjugated manganese-based magnetic engineered iron oxide for imaging of HER2/neu- and EGFR-expressing tumors	Theranostics. 2016 Jan 1;6(1):118-130.
2015-10	Identification of substituted naphthotriazolediones as novel tryptophan 2,3-dioxygenase (TDO) inhibitors through structure-based virtual screening	Journal of Medicinal Chemistry. 2015 Oct;58 (19):7807-7819.

显示项目26-50 / 215. (共9页) << < 1 2 3 4 5 6 7 8 9 > >> 每页显示[10|25|50]项目