| 2009-02-01 |
1,2,3-Triazole derivatives as new cannabinoid CB1 receptor antagonists |
Bioorganic and Medicinal Chemistry Letters. 2009 Feb 1;19(3):1022-1025. |
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| 2009-02 |
Involvement of oxidative stress and activation of aryl hydrocarbon receptor in elevation of CYP1A1 expression and activity in lung cells and tissues by arsenic: An in vitro and in vivo study |
Toxicological Sciences. 2009 Feb;107(2):385-393. |
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| 2009-02 |
Aurintricarboxylic acid inhibits influenza virus neuraminidase |
Antiviral Research. 2009 Feb;81(2):123-131. |
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| 2009-02 |
A novel dengue vaccine candidate that induces cross-neutralizing antibodies and memory immunity |
Microbes and Infection. 2009 Feb;11(2):288-295. |
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| 2009-01-22 |
Pyrrolidine compounds |
AU2005221678/2009-01-22 |
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| 2009-01 |
Far upstream element binding protein 2 interacts with enterovirus 71 internal ribosomal entry site and negatively regulates viral translation |
Nucleic Acids Ressearch. 2009 Jan;37(1):47-59. |
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| 2009 |
Thiopurine analogue inhibitors of severe acute respiratory syndrome-coronavirus papain-like protease, a deubiquitinating and deISGylating enzyme |
Antiviral Chemistry and Chemotherapy. 2009;19(4):151-156. |
|
| 2009 |
A concise total synthesis of (±)-acutifolone A |
Organic and Biomolecular Chemistry. 2009;7(16):3285-3290. |
|
| 2008-12-25 |
Synthesis and structure-activity relationships of 2-amino-1-aroylnaphthalene and 2-hydroxy-1-aroylnaphthalenes as potent antitubulin agents |
Journal of Medicinal Chemistry. 2008 Dec 25;51(24):8163-8167. |
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| 2008-12-11 |
吲哚化合物 |
I304066/2008-12-11 |
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| 2008-12-09 |
Imidazolamino compounds |
US7462723B2/2008-12-09 |
|
| 2008-12 |
Development of antiviral agents for enteroviruses |
Journal of Antimicrobial Chemotherapy. 2008 Dec;62(6):1169-1173. |
|
| 2008-12 |
Potent activation of large-conductance Ca2+-activated K + channels by the diphenylurea 1,3-bis-[2-hydroxy-5-(trifluoromethyl) phenyl]urea (NS1643) in pituitary tumor (GH3) cells |
Molecular Pharmacology. 2008 Dec;74(6):1696-1704. |
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| 2008-12 |
Mana-Hox displays anticancer activity against prostate cancer cells through tubulin depolymerization and DNA damage stress |
Naunyn-Schmiedeberg's Archives of Pharmacology. 2008 Dec;378(6):599-608. |
|
| 2008-11-28 |
Anti-angiogenic action of 5,5-diphenyl-2-thiohydantoin-N10 (DPTH-N10) |
Cancer Letters. 2008 Nov 28;271(2):294-305. |
|
| 2008-11-25 |
Anti-tumor compounds |
US7456289B2/2008-11-25 |
|
| 2008-11-11 |
Indole compounds |
US7449478B2/2008-11-11 |
|
| 2008-11 |
Amantadine as a regulator of internal ribosome entry site |
Acta Pharmacologica Sinica. 2008 Nov;29(11):1327-1333. |
|
| 2008-10-15 |
Analogues of 2-phenyl-ethenesulfonic acid phenyl ester have dual functions of inhibiting expression of inducible nitric oxide synthase and activating peroxisome proliferator-activated receptor gamma |
Bioorganic and Medicinal Chemistry Letters. 2008 Oct 15;18(20):5676-5679. |
|
| 2008-09-21 |
Bioisosteric replacement of the pyrazole 3-carboxamide moiety of rimonabant. A novel series of oxadiazoles as CB1 cannabinoid receptor antagonists |
Organic and Biomolecular Chemistry. 2008 Sep 21;6(18):3399-3407. |
|
| 2008-09-16 |
Pyrrolidine compounds |
US7425633B2/2008-09-16 |
|
| 2008-09-11 |
Bioisosteric replacement of the pyrazole 5-aryl moiety of N-(piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (SR141716A). A novel series of alkynylthiophenes as potent and selective cannabinoid-1 receptor antagonists |
Journal of Medicinal Chemistry. 2008 Sep 11;51(17):5397-5412. |
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| 2008-09 |
Human breast tumor cells express multimodal imaging reporter genes |
Molecular Imaging and Biology. 2008 Sep;10(5):253-263. |
|
| 2008-08-01 |
Design, synthesis, and evaluation of 3C protease inhibitors as anti-enterovirus 71 agents |
Bioorganic and Medicinal Chemistry. 2008 Aug 1;16(15):7388-7398. |
|
| 2008-08 |
A three-dimensional pharmacophore model for dipeptidyl peptidase IV inhibitors |
European Journal of Medicinal Chemistry. 2008 Aug;43(8):1603-1611. |
|
| 2008-07-24 |
Discovery of 4-amino and 4-hydroxy-1-aroylindoles as potent tubulin polymerization inhibitors |
Journal of Medicinal Chemistry. 2008 Jul;51(14):4351-4355. |
|
| 2008-07-21 |
吡咯啉啶化合物 |
I299039/2008-07-21 |
|
| 2008-07-15 |
Inhibitors of dipeptidyl peptidase 8 and dipeptidyl peptidase 9. Part 1: Identification of dipeptide derived leads |
Bioorganic and Medicinal Chemistry Letters. 2008 Jul;18(14):4154-4158. |
|
| 2008-07-15 |
Inhibitors of dipeptidyl peptidase 8 and dipeptidyl peptidase 9. Part 2: Isoindoline containing inhibitors |
Bioorganic and Medicinal Chemistry Letters. 2008 Jul;18(14):4159-4162. |
|
| 2008-07-09 |
Enhanced oral bioavailability of paclitaxel by D-alpha-tocopheryl polyethylene glycol 400 succinate in mice |
International Journal of Pharmaceutics. 2008 Jul;359(1-2):174-181. |
|
| 2008-07-08 |
Use of 1H-indol-3-yl-2-oxoacetamide compounds |
US7396838B2/2008-07-08 |
|
| 2008-07-01 |
Pyrrolidine compounds |
KR10-0844593/2008-07-01 |
|
| 2008-07 |
Anti-HSV activity of digitoxin and its possible mechanisms |
Antiviral Research. 2008 Jul;79(1):62-70. |
|
| 2008-07 |
Computational and ultrastructural toxicology of a nanoparticle, Quantum Dot 705, in mice |
Environmental Science and Technology. 2008 Jul;42(16):6264-6270. |
|
| 2008-07 |
Chemical constituents and cytotoxic activity of the root of Antidesma hiiranense |
Planta Medica. 2008 Jul;74(9):1076. |
|
| 2008-07 |
Chemical constituents from a cytotoxic root extract of Anneslea lanceolata |
Planta Medica. 2008 Jul;74(9):1059. |
|
| 2008-07 |
Secondary metabolites and cytotoxic activity of the stem bark of Litsea akoensis |
Planta Medica. 2008 Jul;74(9):1071. |
|
| 2008-07 |
Chemical constituents and cytotoxic activity of the root wood of Magnolia kachirachirai |
Planta Medica. 2008 Jul;74(9):1071. |
|
| 2008-07 |
Secondary metabolites and cytotoxic activities from the stem bark of Zanthoxylum nitidum |
Planta Medica. 2008 Jul;74(9):1046. |
|
| 2008-06-01 |
A cell-based high-throughput screen for epidermal growth factor receptor pathway inhibitors |
Analytical Biochemistry. 2008 Jun;377(1):89-94. |
|
| 2008-06 |
Cytotoxic constituents from the root wood of formosan Michelia compressa |
Journal of the Chilean Chemical Society. 2008 Jun;53(2):1523-1524. |
|
| 2008-06 |
Oral delivery of peptide drugs using nanoparticles self-assembled by poly(gamma-glutamic acid) and a chitosan derivative functionalized by trimethylation |
Bioconjugate Chemistry. 2008 Jun;19(6):1248-1255. |
|
| 2008-06 |
Synthesis, beta-adrenergic receptor binding and antihypertensive potential of vanillin-derived phenoxypropanolamines |
Indian Journal of Chemistry Section B: Organic Chemistry Including Medicinal Chemistry. 2008 Jun;47(6):903-909. |
|
| 2008-05-01 |
Purification and characterization of a dipeptidyl peptidase 9-like enzyme from bovine testes |
Frontiers in Bioscience. 2008 May 1;13(9):3558-3568. |
|
| 2008-05-01 |
抗腫瘤化合物 |
I296195/2008-05-01 |
|
| 2008-05 |
Antiviral activity of pyridyl imidazolidinones against enterovirus 71 variants |
Journal of Biomedical Science. 2008 May;15(3):291-300. |
|
| 2008-05 |
Bioassay-guided purification and identification of PPARa/gamma agonists from Chlorella sorokiniana |
Phytotherapy Research. 2008 May;22(5):605-613. |
|
| 2008-05 |
High-performance liquid chromatography-electrospray mass spectrometry for the simultaneous determination of multiple active components in Sheng-Mai San, a prescription of traditional Chinese medicine |
Phytochemical Analysis. 2008 May-Jun;19(3):258-265. |
|
| 2008-04-15 |
Thiopurine analogues inhibit papain-like protease of severe acute respiratory syndrome coronavirus |
Biochemical Pharmacology. 2008 Apr;75(8):1601-1609. |
|
| 2008-04-06 |
COMP 266-Structure, function and inhibitors of prolyl dipeptidase DPP8 |
Abstracts of Papers - American Chemical Society. 2008 Apr 6;235:266-COMP. |
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