2018-07 |
An intestinal "Transformers"-like nanocarrier system for enhancing the oral bioavailability of poorly water-soluble drugs |
ACS Nano. 2018 Jul;12(7):6389-6397. |
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2018-07 |
4-Bromophenylhydrazinyl benzenesulfonylphenylureas inhibit indoleamine 2,3-dioxygenase in vitro and in vivo |
Cancer Research. 2018 Jul;78(13, Suppl.):Meeting Abstract 1664. |
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2018-07 |
Clinical candidate DBPR112: A novel epidermal growth factor receptor inhibitor as a promising treatment for non-small cell lung cancer |
Cancer Research. 2018 Jul;78(13, Suppl.):Meeting Abstract 4789. |
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2018-07 |
Blockage of EGFR signaling repurposes tumor metabolism through suppression of glycolysis and Kreb cycle in head and neck cancer |
Cancer Research. 2018 Jul;78(13, Suppl.):Meeting Abstract 3944. |
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2018-06-15 |
2-Aroylquinoline-5,8-diones as potent anticancer agents displaying tubulin and heat shock protein 90 (HSP90) inhibition [Erratum: Organic and Biomolecular Chemistry. 2016 Jan;14(2):716-723.] |
Organic and biomolecular chemistry. 2018 Jun 15;16:4734. |
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2018-05-22 |
Total synthesis of tetarimycin A, (±)-Naphthacemycin A9, and (±)-Fasamycin A: structure-activity relationship studies against drug-resistant bacteria |
Journal of Organic Chemistry. 2018 May 22;83(12):6508-6523. |
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2018-05-10 |
Design and synthesis of BPR1K653 derivatives targeting the back pocket of Aurora kinases for selective isoform inhibition |
European Journal of Medicinal Chemistry. 2018 May 10;151:533-545. |
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2018-04-25 |
Challenging clinically unresponsive medullary thyroid cancer: Discovery and pharmacological activity of novel RET inhibitors |
European Journal of Medicinal Chemistry. 2018 Apr 25;150:491-505. |
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2018-04 |
Effects of female sex hormones on folic acid-induced anti-angiogenesis |
Acta Physiologica. 2018 Apr;222:Article number e13001. |
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2018-04 |
4-Bromophenylhydrazinyl benzenesulfonylphenylureas as indoleamine 2,3-dioxygenase inhibitors with in vivo target inhibition and anti-tumor efficacy |
Bioorganic Chemistry. 2018 Apr;77:600-607. |
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2018-04 |
PSPC1 mediates TGF-beta1 autocrine signalling and Smad2/3 target switching to promote EMT, stemness and metastasis |
Nature Cell Biology. 2018 Apr;20(4):479-491. |
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2018-02-08 |
Development of stem-cell-mobilizing agents targeting CXCR4 receptor for peripheral blood stem cell transplantation and beyond |
Journal of Medicinal Chemistry. 2018 Feb 8;61(3):818-833. |
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2018-01-23 |
Identification of danthron as an isoform-specific inhibitor of HEME OXYGENASE-1/cytochrome P450 reductase interaction with anti-tumor activity |
Journal of Biomedical Science. 2018 Jan 23;25:Article number 6. |
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2018-01-01 |
Identification of an oxime-containing C-glucosylarene as a potential inhibitor of sodium-dependent glucose co-transporter 2 |
European Journal of Medicinal Chemistry. 2018 Jan 1;143:611-620. |
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2018-01 |
Discovery and development of DBPR112 as a clinical candidate: A novel EGFR inhibitor for non-small cell lung cancer |
Cancer Science. 2018 Jan;109(Suppl. 1):739. |
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2017-12 |
Stimulatory actions of a novel thiourea derivative on large-conductance, calcium-activated potassium channels |
Journal of Cellular Physiology. 2017 Dec;232(12):3409-3421. |
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2017-12 |
Enhanced B-Raf-mediated NRF2 gene transcription and HATs-mediated NRF2 protein acetylation contributes to ABCC1-mediated chemoresistance and glutathione-mediated survival in acquired topoisomerase II poison-resistant cancer cells |
Free Radical Biology and Medicine. 2017 Dec;113:505-518. |
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2017-11 |
Caveolin-1 secreted from adipose tissues and adipocytes functions as an adipogenesis enhancer |
Obesity. 2017 Nov;25(11):1932-1940. |
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2017-10 |
Identification of anti-viral activity of the cardenolides, Na+/K+-ATPase inhibitors, against porcine transmissible gastroenteritis virus |
Toxicology and Applied Pharmacology. 2017 Oct;332:129-137. |
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2017-09-26 |
Identification of neuraminidase inhibitors against dual H274Y/I222R mutant strains |
Scientific Reports. 2017 Sep 26;7:Article number 12336. |
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2017-09 |
trans-stilbene C-glycosides: Synthesis by a microwave-assisted heck reaction and evaluation of the SGLT-2 inhibitory activity |
Asian Journal of Organic Chemistry. 2017 Sep;6(9):1308-1321. |
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2017-09 |
Outer nuclear membrane protein Kuduk modulates the LINC complex and nuclear envelope architecture |
Journal of Cell Biology. 2017 Sep;216(9):2827-2841. |
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2017-09 |
Adaptation of influenza A (H7N9) virus in primary human airway epithelial cells |
Scientific Reports. 2017 Sep;7:Article number 11300. |
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2017-08-11 |
Targeting P-glycoprotein: Investigation of piperine analogs for overcoming drug resistance in cancer |
Scientific Reports. 2017 Aug 11;7:Article number 7972. |
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2017-08-07 |
Utrophin compensates dystrophin loss during mouse spermatogenesis |
Scientific Reports. 2017 Aug 7;7:Article number 7372. |
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