| 2007-02 |
Anti-inflammatory effects of 7-methoxyl-cryptopleurine and structure-activity relationships of phenanthroindolizidines and phenanthroquinolizidine |
第15屆細胞及分子生物新知研討會. 2007 Feb 1-3. |
|
| 2007-01 |
Preparation and characterization of nanoparticles shelled with chitosan for oral insulin delivery |
Biomacromolecules. 2007 Jan;8(1):146-152. |
 |
| 2007 |
A convenient new procedure for converting primary amides into nitriles |
Chemical Communications. 2007 (3):301-303. |
|
| 2007 |
Crystal structures and computer screened inhibitors of Helicobacter pylori undecaprenyl pyrophosphate synthase |
Frontiers in the Convergence of Bioscience and Information Technologies, FBIT 2007. 2007:305-310(Article number 4524124). |
|
| 2006-12-15 |
Investigation of the dimer interface and substrate specificity of prolyl dipeptidase DPP8 |
Journal of Biological Chemistry. 2006 Dec;281(50):38653-38662. |
|
| 2006-12 |
Pharmacokinetics of anti-SARS-CoV agent niclosamide and its analogs in rats |
Journal of Food and Drug Analysis. 2006 Dec;14(4):329-333. |
|
| 2006-12 |
Biochemical properties of recombinant prolyl dipeptidases DPP-IV and DPP8 |
Advances in Experimental Medicine and Biology. 2006 Dec;575:27-32. |
|
| 2006-11-25 |
The inhibitory effect of polyunsaturated fatty acids on human CYP enzymes |
Life Sciences. 2006 Nov;79(26):2432-2440. |
|
| 2006-11-16 |
7-aroyl-aminoindoline-1-sulfonamides as a novel class of potent antitubulin agents |
Journal of Medicinal Chemistry. 2006 Nov;49(23):6656-6659. |
|
| 2006-11 |
Phase I and pharmacokinetic study of oral thalidomide in patients with advanced hepatocellular carcinoma |
Cancer Chemotherapy and Pharmacology. 2006 Nov;58(5):654-664. |
|
| 2006-11 |
Combined modalities of resistance in an oxaliplaitin-resistant human gastric cancer cell line with enhanced sensitivity |
EJC Supplements. 2006 Nov;4(12):59. |
|
| 2006-10-31 |
Imidazolidinone compounds |
US7129359B2/2006-10-31 |
|
| 2006-10-19 |
Structural basis for the structure-activity relationships of peroxisome proliferator-activated receptor agonists |
Journal of Medicinal Chemistry. 2006 Oct;49(21):6421-6424. |
|
| 2006-10 |
Micropropagation of red sanders (Pterocarpus santalinus L.) using mature nodal explants |
Journal of Forest Research. 2006 Oct;11(5):329-335. |
|
| 2006-10 |
Structure-activity relationship studies of 3-aroylindoles as potent antimitotic agents |
ChemMedChem. 2006 Oct;1(10):1106-1118. |
|
| 2006-09-19 |
Imidazolamino compounds |
US7109227B2/2006-09-19 |
|
| 2006-09 |
MEDI 416-3- 2-((2S)-2-Cyano-pyrrolidin-1-yl)-2-oxo-ethylamino -3-methyl-butyr amide analogs as DPP-IV inhibitors for the treatment of type-II diabetes |
Abstracts of Papers - American Chemical Society. 2006 Sep;232:MEDI 416. |
|
| 2006-08-24 |
Structure-based drug design and structural biology study of novel nonpeptide inhibitors of severe acute respiratory syndrome coronavirus main protease |
Journal of Medicinal Chemistry. 2006 Aug;49(17):5154-5161. |
|
| 2006-08-01 |
抗腸病毒化合物 |
I259083/2006-08-01 |
|
| 2006-08 |
Impaired phagocytosis of capsular serotypes K1 or K2 Klebsiella pneumoniae in type 2 diabetes mellitus patients with poor glycemic control |
Journal of Clinical Endocrinology and Metabolism. 2006 Aug;91(8):3084-3087. |
|
| 2006-07 |
Non-lethal Candida albicans cph1/cph1 efg1/efg1 transcription factor mutant establishing restricted zone of infection in a mouse model of systemic infection |
International Journal of Immunopathology and Pharmacology. 2006 Jul-Sep;19(3):561-565. |
|
| 2006-07 |
Antiviral drug discovery against SARS-CoV |
Current Medicinal Chemistry. 2006 Jul;13(17):2003-2020. |
|
| 2006-06-15 |
Discovery of a novel family of SARS-CoV protease inhibitors by virtual screening and 3D-QSAR studies |
Journal of Medicinal Chemistry. 2006 Jun;49(12):3485-3495. |
|
| 2006-06-15 |
Substituted pyrrolidine-2,4-dicarboxylic acid amides as potent dipeptidyl peptidase IV inhibitors |
Bioorganic and Medicinal Chemistry Letters. 2006 Jun;16(12):3268-3272. |
|
| 2006-06-13 |
Identification of hydrophobic residues critical for DPP-IV dimerization |
Biochemistry. 2006 Jun;45(23):7006-7012. |
|
| 2006-06 |
Synthesis and cytotoxicity studies of cyclohepta[b]indoles, benzo[6,7]cyclohepta[1,2-b]indoles, indeno[1,2-b]indoles, and benzo[a]carbazoles |
Journal of the Chinese Chemical Society. 2006 Jun;53(3):647-662. |
|
| 2006-05-04 |
Structure-based drug design of a novel family of PPAR gamma partial agonists: Virtual screening, X-ray crystallography, and in vitro/in vivo biological activities |
Journal of Medicinal Chemistry. 2006 May;49(9):2703-2712. |
|
| 2006-05 |
Antitubulin agents for the treatment of cancer - a medicinal chemistry update |
Expert Opinion on Therapeutic Patents. 2006 May;16(5):647-691. |
|
| 2006-04-19 |
用於治療黃病毒科病毒感染之醫藥組合物、套組、及包裝產品 |
ZL03138694.6/2006-04-19 |
|
| 2006-04 |
Chromatin-binding in vivo of the erythroid kruppel-like factor, EKLF, in the murine globin loci |
Cell Research. 2006 Apr;16(4):347-355. |
|
| 2006-04 |
Use of the sex ratio as a means of resource assessment for the Japanese eel Anguilla japonica: A case study in the Kaoping River, Taiwan |
Zoological Studies. 2006 Apr;45(2):255-263. |
|
| 2006-04 |
Analysis of the structure-activity relationships between phenanthroindolizidines and phenanthroquinolizidines |
FASEB Journal. 2006 Apr 1-5;20(5):LB492. |
|
| 2006-03 |
Anti-inflammatory mechanisms of phenanthroindolizidine alkaloids |
Molecular Pharmacology. 2006 Mar;69(3):749-758. |
|
| 2006-03 |
Paclitaxel-loaded poly(gamma-glutamic acid)-poly(lactide) nanoparticles as a targeted drug delivery system for the treatment of liver cancer |
Biomaterials. 2006 Mar;27(9):2051-2059. |
|
| 2006-03 |
Paclitaxel-loaded poly(gamma-glutamic acid)-poly(lactide) nanoparticles as a targeted drug delivery system against cultured HepG2 cells |
Bioconjugate Chemistry. 2006 Mar;17(2):291-299. |
|
| 2006-02-09 |
Indol-1-yl acetic acids as peroxisome proliferator-activated receptor agonists: Design, synthesis, structural biology, and molecular docking studies |
Journal of Medicinal Chemistry. 2006 Feb;49(3):1212-1216. |
|
| 2006-02 |
Stable RNA interference in Spodoptera frugiperda cells by a DNA vector-based method |
Biotechnology Letters. 2006 Feb;28(4):271-277. |
|
| 2006-01-12 |
2-[3-[2-[(2S)-2-cyano-1-pyrrolidinyl]-2-oxoethylamino]-3-methyl-1-oxobutyl]-1,2,3,4-tetrahydroisoquinoline: A potent, selective, and orally bioavailable dipeptide-derived inhibitor of dipeptidyl peptidase IV |
Journal of Medicinal Chemistry. 2006 Jan;49(1):373-380. |
|
| 2006-01-01 |
Synthesis and anti-viral activity of a series of sesquiterpene lactones and analogues in the subgenomic HCV replicon system |
Bioorganic and Medicinal Chemistry. 2006 Jan 1;14(1):83-91. |
|
| 2006-01 |
Interaction of Moloney murine leukemia virus capsid with Ubc9 and PIASy mediates SUMO-1 addition required early in infection |
Journal of Virology. 2006 Jan;80(1):342-352. |
|
| 2006 |
Expedient synthesis and structure-activity relationships of phenanthroindolizidine and phenanthroquinolizidine alkaloids |
Organic and Biomolecular Chemistry. 2006;4(5):860-867. |
|
| 2006 |
Antiviral drug discovery targeting to viral proteases |
Current Pharmaceutical Design. 2006;12(11):1301-1314. |
|
| 2005-12-29 |
Novel indole-based peroxisome proliferator-activated receptor agonists: Design, SAR, structural biology, and biological activities |
Journal of Medicinal Chemistry. 2005 Dec;48(26):8194-8208. |
|
| 2005-12-15 |
The effect of N-terminal truncation on double-dimer assembly of goose delta-crystallin |
Biochemical Journal. 2005 Dec;392(Pt. 3):545-554. |
|
| 2005-11 |
Emergence of mutation clusters in the HCV genome during sequential viral passages in Sip-L expressing cells |
Journal of Virological Methods. 2005 Nov;129(2):170-177. |
|
| 2005-10-15 |
Synthesis, antiproliferative, and vasorelaxing evaluations of coumarin alpha-methylene-gamma-butyrolactones |
Bioorganic and Medicinal Chemistry. 2005 Oct;13(20):5710-5716. |
|
| 2005-10-01 |
Synthesis and antipicornavirus activity of (R)- and (S)-1-[5-(4 '-chlorobiphenyl-4-yloxy)-3-methylpentyl]-3-pyridin-4-yl-imidazolidin-2-one |
Bioorganic and Medicinal Chemistry Letters. 2005 Oct;15(19):4206-4211. |
|
| 2005-10 |
Inhibition of hepatitis C virus replication by antimonial compounds |
Antimicrobial Agents and Chemotherapy. 2005 Oct;49(10):4197-4202. |
|
| 2005-08-23 |
Indole compounds |
US6933316B2/2005-08-23 |
|
| 2005-08-02 |
Papain-like protease 2 (PLP2) from severe acute respiratory syndrome coronavirus (SARS-CoV): Expression, purification, characterization, and inhibition |
Biochemistry. 2005 Aug;44(30):10349-10359. |
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