| 2018-07 |
An intestinal "Transformers"-like nanocarrier system for enhancing the oral bioavailability of poorly water-soluble drugs |
ACS Nano. 2018 Jul;12(7):6389-6397. |
 |
| 2018-07 |
4-Bromophenylhydrazinyl benzenesulfonylphenylureas inhibit indoleamine 2,3-dioxygenase in vitro and in vivo |
Cancer Research. 2018 Jul;78(13, Suppl.):Meeting Abstract 1664. |
|
| 2018-07 |
Clinical candidate DBPR112: A novel epidermal growth factor receptor inhibitor as a promising treatment for non-small cell lung cancer |
Cancer Research. 2018 Jul;78(13, Suppl.):Meeting Abstract 4789. |
|
| 2018-07 |
Blockage of EGFR signaling repurposes tumor metabolism through suppression of glycolysis and Kreb cycle in head and neck cancer |
Cancer Research. 2018 Jul;78(13, Suppl.):Meeting Abstract 3944. |
|
| 2018-06-15 |
2-Aroylquinoline-5,8-diones as potent anticancer agents displaying tubulin and heat shock protein 90 (HSP90) inhibition [Erratum: Organic and Biomolecular Chemistry. 2016 Jan;14(2):716-723.] |
Organic and biomolecular chemistry. 2018 Jun 15;16:4734. |
|
| 2018-05-22 |
Total synthesis of tetarimycin A, (±)-Naphthacemycin A9, and (±)-Fasamycin A: structure-activity relationship studies against drug-resistant bacteria |
Journal of Organic Chemistry. 2018 May 22;83(12):6508-6523. |
|
| 2018-05-10 |
Design and synthesis of BPR1K653 derivatives targeting the back pocket of Aurora kinases for selective isoform inhibition |
European Journal of Medicinal Chemistry. 2018 May 10;151:533-545. |
|
| 2018-04-25 |
Challenging clinically unresponsive medullary thyroid cancer: Discovery and pharmacological activity of novel RET inhibitors |
European Journal of Medicinal Chemistry. 2018 Apr 25;150:491-505. |
|
| 2018-04 |
Effects of female sex hormones on folic acid-induced anti-angiogenesis |
Acta Physiologica. 2018 Apr;222:Article number e13001. |
|
| 2018-04 |
4-Bromophenylhydrazinyl benzenesulfonylphenylureas as indoleamine 2,3-dioxygenase inhibitors with in vivo target inhibition and anti-tumor efficacy |
Bioorganic Chemistry. 2018 Apr;77:600-607. |
|
| 2018-04 |
PSPC1 mediates TGF-beta1 autocrine signalling and Smad2/3 target switching to promote EMT, stemness and metastasis |
Nature Cell Biology. 2018 Apr;20(4):479-491. |
|
| 2018-02-08 |
Development of stem-cell-mobilizing agents targeting CXCR4 receptor for peripheral blood stem cell transplantation and beyond |
Journal of Medicinal Chemistry. 2018 Feb 8;61(3):818-833. |
|
| 2018-01-23 |
Identification of danthron as an isoform-specific inhibitor of HEME OXYGENASE-1/cytochrome P450 reductase interaction with anti-tumor activity |
Journal of Biomedical Science. 2018 Jan 23;25:Article number 6. |
|
| 2018-01-01 |
Identification of an oxime-containing C-glucosylarene as a potential inhibitor of sodium-dependent glucose co-transporter 2 |
European Journal of Medicinal Chemistry. 2018 Jan 1;143:611-620. |
|
| 2018-01 |
Discovery and development of DBPR112 as a clinical candidate: A novel EGFR inhibitor for non-small cell lung cancer |
Cancer Science. 2018 Jan;109(Suppl. 1):739. |
|
| 2017-12 |
Stimulatory actions of a novel thiourea derivative on large-conductance, calcium-activated potassium channels |
Journal of Cellular Physiology. 2017 Dec;232(12):3409-3421. |
|
| 2017-12 |
Enhanced B-Raf-mediated NRF2 gene transcription and HATs-mediated NRF2 protein acetylation contributes to ABCC1-mediated chemoresistance and glutathione-mediated survival in acquired topoisomerase II poison-resistant cancer cells |
Free Radical Biology and Medicine. 2017 Dec;113:505-518. |
|
| 2017-11 |
Caveolin-1 secreted from adipose tissues and adipocytes functions as an adipogenesis enhancer |
Obesity. 2017 Nov;25(11):1932-1940. |
|
| 2017-10 |
Identification of anti-viral activity of the cardenolides, Na+/K+-ATPase inhibitors, against porcine transmissible gastroenteritis virus |
Toxicology and Applied Pharmacology. 2017 Oct;332:129-137. |
|
| 2017-09-26 |
Identification of neuraminidase inhibitors against dual H274Y/I222R mutant strains |
Scientific Reports. 2017 Sep 26;7:Article number 12336. |
|
| 2017-09 |
trans-stilbene C-glycosides: Synthesis by a microwave-assisted heck reaction and evaluation of the SGLT-2 inhibitory activity |
Asian Journal of Organic Chemistry. 2017 Sep;6(9):1308-1321. |
|
| 2017-09 |
Outer nuclear membrane protein Kuduk modulates the LINC complex and nuclear envelope architecture |
Journal of Cell Biology. 2017 Sep;216(9):2827-2841. |
|
| 2017-09 |
Adaptation of influenza A (H7N9) virus in primary human airway epithelial cells |
Scientific Reports. 2017 Sep;7:Article number 11300. |
|
| 2017-08-11 |
Targeting P-glycoprotein: Investigation of piperine analogs for overcoming drug resistance in cancer |
Scientific Reports. 2017 Aug 11;7:Article number 7972. |
|
| 2017-08-07 |
Utrophin compensates dystrophin loss during mouse spermatogenesis |
Scientific Reports. 2017 Aug 7;7:Article number 7372. |
|
| 2017-08 |
Hypoxia-induced downregulation of DUSP-2 phosphatase drives colon cancer stemness |
Cancer Research. 2017 Aug;77(16):4305-4316. |
|
| 2017-07-07 |
CCM111, the water extract of Antrodia cinnamomea, regulates immune-related activity through STAT3 and NF-kappaB pathways |
Scientific Reports. 2017 Jul 07;7(1):Article number 4862. |
|
| 2017-07 |
Drug repurposing for chronic myeloid leukemia: In silico and in vitro investigation of DrugBank database for allosteric Bcr-Abl inhibitors |
Journal of Biomolecular Structure and Dynamics. 2017 Jun;35(8):1833-1848. |
|
| 2017-07 |
Design, synthesis, and evaluation of thiazolidine-2,4-dione derivatives as a novel class of glutaminase inhibitors |
Journal of Medicinal Chemistry. 2017 Jul;60(13):5599-5612. |
|
| 2017-07 |
Targeting tumor associated phosphatidylserine with new zinc dipicolylamine-based drug conjugates |
Bioconjugate Chemistry. 2017 Jul;28(7):1878-1892. |
|
| 2017-06-22 |
Targeting coronaviral replication and cellular JAK2 mediated dominant NF-kappaB activation for comprehensive and ultimate inhibition of coronaviral activity |
Scientific Reports. 2017 Jun 22;7:Article number 4105. |
|
| 2017-06 |
Epigallocatechin-3-gallate inhibits bacterial virulence and invasion of host cells |
Bioorganic and Medicinal Chemistry. 2017 Jun;25(11):2883-2887. |
|
| 2017-06 |
Mutagenesis of dengue virus protein NS2A revealed a novel domain responsible for virus-induced cytopathic effect and interactions between NS2A and NS2B transmembrane segments |
Journal of Virology. 2017 Jun;91(12):Article number e01836-16. |
|
| 2017-05-22 |
Bioactive composition of Reevesia formosana root and stem with cytotoxic activity potential |
RSC Advances. 2017 May 22;7(43):27040-27047. |
|
| 2017-05 |
1-(2,4-Dibromophenyl)-3,6,6-trimethyl-1,5,6,7-tetrahydro-4H-indazol-4-one: A novel opioid receptor agonist with less accompanying gastrointestinal dysfunction than morphine |
Anesthesiology. 2017 May;126(5):952-966. |
|
| 2017-04-05 |
In vivo inhibition of influenza A virus replication by RNA interference targeting the PB2 subunit via intratracheal delivery |
PLoS ONE. 2017 Apr 5;12(4):Article number e0174523. |
|
| 2017-04 |
Specificity protein 1-zinc finger protein 179 pathway is involved in the attenuation of oxidative stress following brain injury |
Redox Biology. 2017 Apr;11:135-143. |
|
| 2017-04 |
A novel CXCR4 antagonist CX549 induces neuroprotection in stroke brain |
Cell Transplantation. 2017 Apr;26(4):571-583. |
|
| 2017-04 |
Discovery of BPR1K871-a quinazoline based multi-kinase inhibitor for the treatment of AML and solid tumors: Rational design, synthesis, in vitro and in vivo evaluation |
Abstracts of Papers of the American Chemical Society. 2017 Apr;253:Meeting Abstract 482. |
|
| 2017-04 |
Toward the total syntheses of natural products containing trans-decalin skeleton from masked o-benzoquinone |
Abstracts of Papers of the American Chemical Society. 2017 Apr;253:Meeting Abstract 516. |
|
| 2017-04 |
One-pot tandem oxidative dearomatization/ 4+3 cycloaddition: Masked o-benzoquinone with diaza-oxyallyl cation |
Abstracts of Papers of the American Chemical Society. 2017 Apr;253:Meeting Abstract 185. |
|
| 2017-03 |
Mapping the naloxone binding sites on the mu-opioid receptor using cell-based photocrosslinkers |
Biochimica Et Biophysica Acta(BBA)-Proteins and Proteomics. 2017 Mar;1865(3):336-343. |
|
| 2017-01 |
Discovery, structure-activity relationship studies, and anti-nociceptive effects of N-(1,2,3,4-tetrahydro-1-isoquinolinylmethyl)benzamides as novel opioid receptor agonists |
European Journal of Medicinal Chemistry. 2017 Jan;126:202-217. |
|
| 2017-01 |
A potent, selective, and orally bioavailable HCV NS5A inhibitor for treatment of Hepatitis C Virus: (S)-1-((R)-2-(Cyclopropanecarboxamido)-2-phenylacetyl)-N-(4-phenylthiazo l-2-yl)pyrrolidine-2-carboxamide |
Journal of Medicinal Chemistry. 2017 Jan;60(1):228-247. |
|
| 2016-12-08 |
Bromomethylthioindole inspired carbazole hybrids as promising class of anti-MRSA agents |
ACS Medicinal Chemistry Letters. 2016 Dec 8;7(12):1191-1196. |
|
| 2016-12 |
Discovery of BPR1K871, a quinazoline based, multi-kinase inhibitor for the treatment of AML and solid tumors: Rational design, synthesis, in vitro and in vivo evaluation |
Oncotarget. 2016 Dec;7(52):86239-86256. |
|
| 2016-12 |
Glucocorticoids may compromise the effect of gefitinib in non-small cell lung cancer |
Oncotarget. 2016 Dec;7(52):85917-85928. |
|
| 2016-12 |
Phenyl benzenesulfonylhydrazides: Selective indoleamine 2,3-dioxygenase inhibitors with potent in vivo pharmacodynamic activity and antitumor efficacy |
European Journal of Cancer. 2016 Dec;68(Suppl. 1):S83-S84. |
|
| 2016-12 |
Novel cKIT kinase inhibitor, BPRCKJ001, as an advanced therapeutic candidate for GIST |
Annals of Oncology. 2016 Dec;27(Suppl. 9):Meeting Abstract 2P. |
|
| 2016-11-29 |
Discovery of novel inhibitors of Aurora kinases with indazole scaffold: In silico fragment-based and knowledge-based drug design |
European Journal of Medicinal Chemistry. 2016 Nov 29;124:186-199. |
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