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显示项目51-75 / 152. (共7页) << < 1 2 3 4 5 6 7 > >> 每页显示[10|25|50]项目

日期	题名	關聯
2018-02-08	Development of stem-cell-mobilizing agents targeting CXCR4 receptor for peripheral blood stem cell transplantation and beyond	Journal of Medicinal Chemistry. 2018 Feb 8;61(3):818-833.
2018-01-01	Identification of an oxime-containing C-glucosylarene as a potential inhibitor of sodium-dependent glucose co-transporter 2	European Journal of Medicinal Chemistry. 2018 Jan 1;143:611-620.
2018-01	Discovery and development of DBPR112 as a clinical candidate: A novel EGFR inhibitor for non-small cell lung cancer	Cancer Science. 2018 Jan;109(Suppl. 1):739.
2017-08-11	Targeting P-glycoprotein: Investigation of piperine analogs for overcoming drug resistance in cancer	Scientific Reports. 2017 Aug 11;7:Article number 7972.
2017-07	Design, synthesis, and evaluation of thiazolidine-2,4-dione derivatives as a novel class of glutaminase inhibitors	Journal of Medicinal Chemistry. 2017 Jul;60(13):5599-5612.
2017-07	Targeting tumor associated phosphatidylserine with new zinc dipicolylamine-based drug conjugates	Bioconjugate Chemistry. 2017 Jul;28(7):1878-1892.
2017-05	1-(2,4-Dibromophenyl)-3,6,6-trimethyl-1,5,6,7-tetrahydro-4H-indazol-4-one: A novel opioid receptor agonist with less accompanying gastrointestinal dysfunction than morphine	Anesthesiology. 2017 May;126(5):952-966.
2017-04	Discovery of BPR1K871-a quinazoline based multi-kinase inhibitor for the treatment of AML and solid tumors: Rational design, synthesis, in vitro and in vivo evaluation	Abstracts of Papers of the American Chemical Society. 2017 Apr;253:Meeting Abstract 482.
2017-01	Discovery, structure-activity relationship studies, and anti-nociceptive effects of N-(1,2,3,4-tetrahydro-1-isoquinolinylmethyl)benzamides as novel opioid receptor agonists	European Journal of Medicinal Chemistry. 2017 Jan;126:202-217.
2017-01	A potent, selective, and orally bioavailable HCV NS5A inhibitor for treatment of Hepatitis C Virus: (S)-1-((R)-2-(Cyclopropanecarboxamido)-2-phenylacetyl)-N-(4-phenylthiazo l-2-yl)pyrrolidine-2-carboxamide	Journal of Medicinal Chemistry. 2017 Jan;60(1):228-247.
2016-12-08	Bromomethylthioindole inspired carbazole hybrids as promising class of anti-MRSA agents	ACS Medicinal Chemistry Letters. 2016 Dec 8;7(12):1191-1196.
2016-12	Discovery of BPR1K871, a quinazoline based, multi-kinase inhibitor for the treatment of AML and solid tumors: Rational design, synthesis, in vitro and in vivo evaluation	Oncotarget. 2016 Dec;7(52):86239-86256.
2016-12	Phenyl benzenesulfonylhydrazides: Selective indoleamine 2,3-dioxygenase inhibitors with potent in vivo pharmacodynamic activity and antitumor efficacy	European Journal of Cancer. 2016 Dec;68(Suppl. 1):S83-S84.
2016-12	Novel cKIT kinase inhibitor, BPRCKJ001, as an advanced therapeutic candidate for GIST	Annals of Oncology. 2016 Dec;27(Suppl. 9):Meeting Abstract 2P.
2016-09	Activation of delta-opioid receptor contributes to the antinociceptive effect of oxycodone in mice	Pharmacological Research. 2016 Sep;111:867-876.
2016-07	In vitro and in vivo studies of a potent capsid-binding inhibitor of enterovirus 71	Journal of Antimicrobial Chemotherapy. 2016 Jul;71(7):1922-1932.
2016-05	N-Indolylglycosides bearing modifications at the glucose C6-Position as Sodium-Dependent Glucose Co-transporter 2 inhibitors	Bioorganic and Medicinal Chemistry. 2016 May;24(10):2242-2250.
2016-01	2-Aroylquinoline-5,8-diones as potent anticancer agents displaying tubulin and heat shock protein 90 (HSP90) inhibition	Organic and Biomolecular Chemistry. 2016 Jan;14(2):716-723.
2016-01	Phenyl benzenesulfonylhydrazides exhibit selective Indoleamine 2,3-Dioxygenase inhibition with potent in vivo pharmacodynamic activity and antitumor efficacy	Journal of Medicinal Chemistry. 2016 Jan;59(1):419-430.
2015-10	Identification of substituted naphthotriazolediones as novel tryptophan 2,3-dioxygenase (TDO) inhibitors through structure-based virtual screening	Journal of Medicinal Chemistry. 2015 Oct;58 (19):7807-7819.
2015-08	Novel Nrf2/ARE activator, trans-coniferylaldehyde, induces a HO-1-mediated defense mechanism through a dual p38alpha/MAPKAPK-2 and PK-N3 signaling pathway	Chemical Research in Toxicology. 2015 Aug ;28(9):1681-1692.
2015-08	Zinc-dipicolylamine directed pharmaceutical delivery system (ZAPS) as an innovative cancer drug delivery platform	Cancer Research. 2015 Aug;75(Suppl. 15):Abstract number 4413.
2015-08	Optimization of quinazoline-based kinase inhibitors: Identification of a dual FLT3/AURKA kinase inhibitor for the treatment of acute myeloid leukemia	Abstracts of Papers of the American Chemical Society. 2015 Aug;250:Meeting Abstract 490.
2015-07	Identification of a potent 5-phenyl-thiazol-2-ylamine-based inhibitor of FLT3 with activity against drug resistance-conferring point mutations	European Journal of Medicinal Chemistry. 2015 Jul;100:151-161.
2015-01	1-Arylsulfonyl-5-(N-hydroxyacrylamide)tetrahydroquinolines as potent histone deacetylase inhibitors suppressing the growth of prostate cancer cells	European Journal of Medicinal Chemistry. 2015 Jan;89:320-330.

显示项目51-75 / 152. (共7页) << < 1 2 3 4 5 6 7 > >> 每页显示[10|25|50]项目