Collection Patents [0/8] Periodical Articles [119/120] Conference Papers/Meeting Abstract [14/24] Siblings Su-Ying Wu [52/65] Others [58/60] Kak-Shan Shia [76/98] Yueh Andrew Yueh [29/32] Chung-Ming Chang [7/9] Jang-Yang Chang [18/18] Chun-Ping Chang [21/26] John Tsu-An Hsu [170/215] Shiow-Ju Lee [75/105] Jinq-Chyi Lee [23/24] Shu-Yu Lin [19/20] Ming-Shiu Hung [31/40] Shiow-Lin Pan(2009-2013) [16/17] Wen-Chieh Wang [13/15] Hung-Jung Wang [7/7] Chuan Shih(2014-2017) [35/39] Chun-Wei Tung [23/23] Ya-Hui Chi [21/25] Shau-Hua Ueng [22/24] Hong Zhuang [1/1] Shiu-Hwa Yeh [24/25] Weir-Torn Jiaang [41/66] Hsing-Pang Hsieh [171/231] Yu-Sheng Chao(2002-2013) [120/212] Ching-Chuan Kuo [49/55] Lun Kelvin Tsou [28/29] Jyh-Haur Chern [31/52] Xin Chen(2002-2015) [53/67] Chiung-Tong Chen [180/212] Wan-Ching Yen [6/7] Ming-Chu Hsu(1997-2001) [3/10] Shu-Jung Chen(1998-2001) [3/11] Hua-Chien Chen(1997-2001) [9/9] Community Statistics Item counts issued in 3 years:19(12.50%) Items With Fulltext:133(87.50%) Download counts of the item Download times greater than 0:133(100.00%) Download times greater than 100:128(96.24%) Total Bitstream Download Counts:80343(1.50%) Last Update: 2024-12-01 02:45 Top Upload Loading... Top Download Loading... Recent Submissions DBPR116, a prodrug of BPRMU191, in ... Discovery of a mu-opioid receptor m... Development of a humanized antibody... Discovery of dual MER/AXL kinase in... Discovery of a long half-life AURKA... Discovery of novel AXL and MER inhi... A dual nociceptin and mu opioid rec... Discovery of tetrasubstituted thiop... Development of furanopyrimidine-bas... 2,6-Difluorobenzamide derivatives a...

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Showing items 1-25 of 152. (7 Page(s) Totally) 1 2 3 4 5 6 7 > >> View [10|25|50] records per page

Date	Title	Relation
2024-10-29	DBPR116, a prodrug of BPRMU191, in combination with naltrexone as a safer opioid analgesic than morphine via peripheral administration	Journal of Medicinal Chemistry. 2024 Oct 29;Article in Press.
2024-07-17	Discovery of a mu-opioid receptor modulator that in combination with morphinan antagonists induces analgesia	Cell Chemical Biology. 2024 Jul 17;Article in Press.
2024-07-04	Development of a humanized antibody targeting extracellular HSP90alpha to suppress endothelial-mesenchymal transition-enhanced tumor growth of pancreatic adenocarcinoma cells	Cells. 2024 Jul 04;13(13):Article number 1146.
2024-06-24	Discovery of dual MER/AXL kinase inhibitors as bifunctional small molecules for inhibiting tumor growth and enhancing tumor immune microenvironment	Journal of Medicinal Chemistry. 2024 Jun 24;Article in Press.
2024-06-01	Discovery of a long half-life AURKA inhibitor to treat MYC-amplified solid tumors as a monotherapy and in combination with everolimus	Molecular Cancer Therapeutics. 2024 Jun 01;23(6):766-779.
2023-10-05	Discovery of tetrasubstituted thiophenes as Cisd2 activators: A potential novel therapeutic option in nonalcoholic fatty liver disease	European Journal of Medicinal Chemistry. 2023 Oct 05;258:Article number 115583.
2023-10-05	A dual nociceptin and mu opioid receptor agonist exhibited robust antinociceptive effect with decreased side effects	European Journal of Medicinal Chemistry. 2023 Oct 05;258:Article number 115608.
2023-10	Discovery of novel AXL and MER inhibitors as potential anticancer and immune modulator drugs	Annals of Oncology. 2023 Oct;34(Suppl. 2):S214.
2023-02-07	Development of furanopyrimidine-based orally active third-generation EGFR inhibitors for the treatment of non-small cell lung cancer	Journal of Medicinal Chemistry. 2023 Feb 7;66(4):2566-2588.
2022-12-05	Benzo[b]thiophene-2-carboxamides as novel opioid receptor agonists with potent analgesic effect and reduced constipation	European Journal of Medicinal Chemistry. 2022 Dec 5;243:Article number 114728.
2022-12-05	2,6-Difluorobenzamide derivatives as store-operated calcium channel (SOC) inhibitors	European Journal of Medicinal Chemistry. 2022 Dec 5;243:Article number 114773.
2022-10-13	Targeting the phosphatidylserine-immune checkpoint with a small-molecule maytansinoid conjugate	Journal of Medicinal Chemistry. 2022 Oct 13;65(19):12802-12824.
2022-10-03	Protective effect of CXCR4 antagonist DBPR807 against ischemia-reperfusion injury in a rat and porcine model of myocardial infarction: Potential adjunctive therapy for percutaneous coronary intervention	International Journal of Molecular Sciences. 2022 Oct 3;23(19):Article number 11730.
2022-07-24	Hesperetin promotes longevity and delays aging via activation of Cisd2 in naturally aged mice	Journal of Biomedical Science. 2022 Jul 24;29:Article number 53.
2022-07	Rejuvenating hepatic tumor microenvironment immunity with a phosphatidylserine-targeting small molecule drug conjugate	Biomedicine and Pharmacotherapy. 2022 Jul;151:Article number 113084.
2022-06-21	Synthesis and evaluation of small molecule drug conjugates harnessing thioester-linked maytansinoids	Pharmaceutics. 2022 Jun 21;14(7):Article number 1316.
2022-03-02	Discovery of potential neuroprotective agents against paclitaxel-induced peripheral neuropathy	Journal of Medicinal Chemistry. 2022 Mar 2;65(6):4767-4782.
2022-02-15	Click chemistry and multicomponent reaction for linker diversification of zinc dipicolylamine-based drug conjugates	Frontiers in Chemistry. 2022 Feb 15;9:Article number 822587.
2022-02-05	Discovery and development of a novel N-(3-bromophenyl)-{[(phenylcarbamoyl)amino]methyl}-N-hydroxythiophene-2-carboximidamide indoleamine 2,3-dioxygenase inhibitor using knowledge-based drug design	European Journal of Medicinal Chemistry. 2022 Feb 5;229:Article number 114043.
2021-11-15	Design and synthesis of novel orally selective and type II pan-TRK inhibitors to overcome mutations by property-driven optimization	European Journal of Medicinal Chemistry. 2021 Nov 15;224:Article number 113673.
2021-10-14	Discovery of BPR1R024, an orally active and selective CSF1R inhibitor that exhibits antitumor and immunomodulatory activity in a murine colon tumor model	Journal of Medicinal Chemistry. 2021 Oct 14;64(19):14477-14497.
2021-08-01	DBPR108, a novel dipeptidyl peptidase-4 inhibitor with antihyperglycemic activity	Life Sciences. 2021 Aug 1;278:Article number 119574.
2021-05-19	Discovery and synthesis of a pyrimidine-based aurora kinase inhibitor to reduce levels of MYC oncoproteins	Journal of Medicinal Chemistry. 2021 May 19;64(11):7312-7330.
2021-03-30	A highly selective and potent CXCR4 antagonist for hepatocellular carcinoma treatment	Proceedings of the National Academy of Sciences of the United States of America. 2021 Mar 30;118(13):Article number e2015433118.
2021-01	Overcoming vincristine resistance in cancer: Computational design and discovery of piperine-inspired P-glycoprotein inhibitors	Chemical Biology and Drug Design. 2021 Jan;97(1):51-66.

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