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显示项目26-40 / 40. (共2页) << < 1 2  每页显示[10|25|50]项目

日期	题名	關聯
2012-07-04	噻吩化合物	ZL200780036897.1/2012-07-04
2012-07	Induction of fatty acid oxidation resists weight gain, ameliorates hepatic steatosis and reduces cardiometabolic risk factors	International Journal of Obesity. 2012 Jul;36(7):999-1006.
2011-10-01	硒吩化合物及其醫藥組成物	I349668/2011-10-01
2011-06	A new perspective of cannabinoid 1 receptor antagonists: Approaches toward peripheral CB1R blockers without crossing the blood-brain barrier	Current Topics In Medicinal Chemistry. 2011 Jun;11(12):1421-1429.
2011-03-21	吡唑化合物及其醫藥組成物	I339205/2011-03-21
2011-01-13	Discovery of novel N -Beta- d -Xylosylindole derivatives as sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors for the management of hyperglycemia in diabetes	Journal of Medicinal Chemistry. 2011 Jan 13;54(1):166-178.
2010-11-16	Thiophene compounds	US7834046B2/2010-11-16
2010-10	Biphasic suppression of appetite by cannabinoid CB1 receptor antagonists with distinct functional activities	Pharmacological Research. 2010 Oct;62(4):337-343.
2010-09-28	Selenophene compounds	US7803799B2/2010-09-28
2010-09	Discovery of 1-(2,4-Dichlorophenyl)-4-ethyl-5-(5-(2-(4-(trifluoromethyl)phenyl)ethynyl)thiophe n-2-yl)-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide as a potential peripheral cannabinoid-1 receptor inverse agonist	ChemMedChem. 2010 Sep;5(9):1439-1443.
2009-07-23	Discovery of 2-[5-(4-chloro-phenyl)-1-(2,4-dichloro-phenyl)-4-ethyl-1H-pyrazol-3-yl]-1,5,5-trimethyl-1,5-dihydro-imidazol-4-thione (BPR-890) via an active metabolite. A novel, potent and selective cannabinoid-1 receptor inverse agonist with high antiobesity efficacy in DIO mice	Journal of Medicinal Chemistry. 2009 Jul 23;52(14):4496-4510.
2009-02-01	1,2,3-Triazole derivatives as new cannabinoid CB1 receptor antagonists	Bioorganic and Medicinal Chemistry Letters. 2009 Feb 1;19(3):1022-1025.
2008-09-21	Bioisosteric replacement of the pyrazole 3-carboxamide moiety of rimonabant. A novel series of oxadiazoles as CB1 cannabinoid receptor antagonists	Organic and Biomolecular Chemistry. 2008 Sep 21;6(18):3399-3407.
2008-09-11	Bioisosteric replacement of the pyrazole 5-aryl moiety of N-(piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (SR141716A). A novel series of alkynylthiophenes as potent and selective cannabinoid-1 receptor antagonists	Journal of Medicinal Chemistry. 2008 Sep 11;51(17):5397-5412.
2008-02-07	Design, synthesis, and biological evaluation of novel alkenylthiophenes as potent and selective CB1 cannabinoid receptor antagonists	Organic and Biomolecular Chemistry. 2008 Feb;6(3):447-450.

显示项目26-40 / 40. (共2页) << < 1 2  每页显示[10|25|50]项目