| 2015-05 |
A novel peripheral cannabinoid receptor 1 antagonist, BPR0912, reduces weight independently of food intake and modulates thermogenesis |
Diabetes, Obesity and Metabolism. 2015 May;17(5):495-504. |
 |
| 2015-04-14 |
Fused multicyclic compounds as protein kinase inhibitors |
US9006252/2015-04-14 |
|
| 2015-02-24 |
Pyrazole compounds |
US8962845/2015-02-24 |
|
| 2015-02-11 |
吡唑類化合物 |
TWI472514/2015-02-11 |
|
| 2014-12-01 |
Morphine drives internal ribosome entry site-mediated hnRNP K translation in neurons through opioid receptor-dependent signaling |
Nucleic Acids Research. 2014 Dec 1;42(21):13012-13025. |
|
| 2014-11-19 |
咪唑-4-酮及咪唑-4-硫酮化合物 |
CN101723937/2014-11-19 |
|
| 2014-10-29 |
作為極光激酶抑制劑的稠合雙環嘧啶化合物 |
ZL200980115577.4/2014-10-29 |
|
| 2014-10-21 |
化合物於製造治療病毒感染的藥物之用途 |
TWI457121/2014-10-21 |
|
| 2014-09-01 |
治療阿茲海默症或帕金森氏症之醫藥組成物 |
TWI450716/2014-09-01 |
|
| 2014-09 |
Discovery, structure-activity relationship studies, and anti-nociceptive effects of 1-phenyl-3,6,6-trimethyl-1,5,6,7-tetrahydro-4H-indazol-4-one as novel opioid receptor agonists |
Bioorganic and Medicinal Chemistry. 2014 Sep;22(17): 4694-4703. |
|
| 2014-08-15 |
Anticancer oral formulation |
JP5596680/2014-08-15 |
|
| 2014-08-01 |
Pyrrolidine derivatives |
JP5586484/2014-08-01 |
|
| 2014-08 |
Discovery and structure-activity relationships of phenyl benzenesulfonylhydrazides as novel indoleamine 2,3-dioxygenase inhibitors |
Bioorganic and Medicinal Chemistry Letters. 2014 Aug;24(15):3403-3406. |
|
| 2014-08 |
Discovery of selective inhibitors of Glutaminase-2, which inhibit mTORC1, activate autophagy and inhibit proliferation in cancer cells |
Oncotarget. 2014 Aug;5(15):6087-6101. |
|
| 2014-07-30 |
Pyrazole compounds |
ZA2013/03800/2014-07-30 |
|
| 2014-06-04 |
抗癌口服制剂 |
CN102159541/2014-06-04 |
|
| 2014-05-12 |
Pyrrolidine derivatives |
J/001349/2014-05-12 |
|
| 2014-05-11 |
二苯並〔f,h〕異喹啉衍生物及其醫藥組成物 |
TWI436983/2014-05-11 |
|
| 2014-05-08 |
Pyrrolidine derivatives |
AU2009222198/2014-05-08 |
|
| 2014-04-29 |
Quinoline compounds and their use for treating viral infection |
US8710079/2014-04-29 |
|
| 2014-04-25 |
Pyrrolidine derivatives |
HK1149261/2014-04-25 |
|
| 2014-04-21 |
咪唑-4-酮及咪唑-4-硫酮化合物 |
TWI434686/2014-04-21 |
|
| 2014-04-21 |
作為蛋白質激酶抑制劑之吡唑化合物及噻唑化合物、其醫藥組成物及用途 |
TWI434834/2014-04-21 |
|
| 2014-04-15 |
Glycoside compounds |
US8697658/2014-04-15 |
|
| 2014-03-20 |
Fused bicyclic pyrimidine compounds as aurora kinase inhibitors |
JP5502072/2014-03-20 |
|
| 2014-03-11 |
脯胺酸衍生物 |
TWI429645/2014-03-11 |
|
| 2014-02-19 |
Pyrrolidine derivatives |
EP2252582/2014-02-19 |
|
| 2014-01-08 |
Evaluation of the antitumor effects of BPR1J-340, a potent and selective FLT3 inhibitor, alone or in combination with an HDAC inhibitor, vorinostat, in AML cancer |
PLoS ONE. 2014 Jan 8;9(1):Article number e83160. |
|
| 2013-12-18 |
吡咯烷化合物 |
CN101970402/2013-12-18 |
|
| 2013-11-21 |
治療癌症的醫藥組成物 |
TWI415852/2013-11-21 |
|
| 2013-11-13 |
Discovery of 1-(2,4-Dichlorophenyl)-N-(piperidin-1-yl)-4-((pyrrolidine-1-sulfonamido)methyl)-5 -(5-((4-(trifluoromethyl)phenyl)ethynyl)thiophene-2-yl)-1H-pyrazole-3-carboxamide as a novel peripherally restricted cannabinoid-1 receptor antagonist with significant weight-loss efficacy in diet-induced obese mice |
Journal of Medicinal Chemistry. 2013 Nov 13;56(24):9920-9933. |
|
| 2013-11 |
BPR0C305, an orally active microtubule-disrupting anticancer agent |
Anticancer Drugs. 2013 Nov;24(10):1047-1057. |
|
| 2013-10-01 |
喹啉化合物及包含其之治療病毒感染之醫藥組成物 |
TWI410245/2013-10-01 |
|
| 2013-09-27 |
Pyrrolidine derivatives |
RU2494094/2013-09-27 |
|
| 2013-09-11 |
噻吩化合物及其醫藥組成物 |
TWI408136/2013-09-11 |
|
| 2013-08-21 |
Fused multicyclic compounds as protein kinase inhibitors |
EP2331530/2013-08-21 |
|
| 2013-08-13 |
Fused bicyclic and tricyclic pyrimidine compounds as tyrosine kinase inhibitors |
US8507502/2013-08-13 |
|
| 2013-07-16 |
Dibenzo[f,h]isoquinoline derivatives |
US8486959/2013-07-16 |
|
| 2013-07-01 |
做為蛋白質激酶抑制劑之稠合多環化合物 |
TWI400242/2013-07-01 |
|
| 2013-06-28 |
Optimization of ligand and lipophilic efficiency to identify an in vivo active furano-pyrimidine aurora kinase inhibitor |
Journal of Medicinal Chemistry. 2013 Jun 28;56(13):5247-5260. |
|
| 2013-06-05 |
Anticancer oral formulation |
EP2310363/2013-06-05 |
|
| 2013-06 |
c-Jun-mediated anti-cancer mechanisms of tylophorine |
Carcinogenesis. 2013 Jun;34(6):1304-1314. |
|
| 2013-06 |
Discovery of 3-phenyl-1H-5-pyrazolylamine derivatives containing a urea pharmacophore as potent and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3) |
Bioorganic and Medicinal Chemistry. 2013 Jun;21(11):2856-2867. |
|
| 2013-05 |
Characterization of an efficient dengue virus replicon for development of assays of discovery of small molecules against dengue virus |
Antiviral Research. 2013 May;98(2):228-241. |
|
| 2013-05 |
Aurora kinase inhibitors reveal mechanisms of HURP in nucleation of centrosomal and kinetochore microtubules |
Proceedings of the National Academy of Sciences of the United States of America. 2013 May;110(19):E1779-E1787. |
|
| 2013-05 |
Protein kinase inhibitor design by targeting the Asp-Phe-Gly (DFG) motif: The role of the DFG motif in the design of epidermal growth factor receptor inhibitors |
Journal of Medicinal Chemistry. 2013 May;56(10):3889-3903. |
|
| 2013-04-30 |
Pyrrolidine derivatives |
SG164613/2013-04-30 |
|
| 2013-04-13 |
Exploration of the role of tylophorine E ring in anti-Coronavirus activity-Tylophorine derived dibenzoquinolines impart multi-biological activities as orally active agents |
FASEB Journal. 2013 Apr 13;27:lb71. |
|
| 2013-04-09 |
Proline derivatives |
US8415482/2013-04-09 |
|
| 2013-04-07 |
BPR000K, a novel Aurora kinase inhibitor |
Abstracts of Papers - American Chemical Society. 2013 Apr 7;245:Article number 300-MEDI. |
|
