2017-05 |
1-(2,4-Dibromophenyl)-3,6,6-trimethyl-1,5,6,7-tetrahydro-4H-indazol-4-one: A novel opioid receptor agonist with less accompanying gastrointestinal dysfunction than morphine |
Anesthesiology. 2017 May;126(5):952-966. |
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2017-04 |
A novel CXCR4 antagonist CX549 induces neuroprotection in stroke brain |
Cell Transplantation. 2017 Apr;26(4):571-583. |
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2017-04 |
Discovery of BPR1K871-a quinazoline based multi-kinase inhibitor for the treatment of AML and solid tumors: Rational design, synthesis, in vitro and in vivo evaluation |
Abstracts of Papers of the American Chemical Society. 2017 Apr;253:Meeting Abstract 482. |
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2016-12 |
Discovery of BPR1K871, a quinazoline based, multi-kinase inhibitor for the treatment of AML and solid tumors: Rational design, synthesis, in vitro and in vivo evaluation |
Oncotarget. 2016 Dec;7(52):86239-86256. |
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2016-12 |
Novel cKIT kinase inhibitor, BPRCKJ001, as an advanced therapeutic candidate for GIST |
Annals of Oncology. 2016 Dec;27(Suppl. 9):Meeting Abstract 2P. |
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2016-10 |
BPR1J373, an oral multiple tyrosine kinase inhibitor, targets c-KIT for the treatment of c-KIT driven myeloid leukemia |
Molecular Cancer Therapeutics. 2016 Oct;15(10):2323-2333. |
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2016-10 |
Multifunctional nanoparticles for oral protein drug delivery |
Diabetes Research and Clinical Practice. 2016 Oct;120(Suppl. 1):S19. |
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2016-08 |
Dipeptidyl peptidase-4 inhibitor LAF-237 improves glucose tolerance and expends graft beta cell mass in diabetic mice transplanted with a sufficient number of islets |
Diabetologia. 2016 Aug;59(Suppl. 1):S198. |
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2016-07-12 |
Dipicolylamine derivatives and their pharmaceutical uses |
US9388193/2016-07-12 |
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2016-05-30 |
항암 경구 제제 |
KR10-1627382/2016-05-30 |
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2016-05 |
N-Indolylglycosides bearing modifications at the glucose C6-Position as Sodium-Dependent Glucose Co-transporter 2 inhibitors |
Bioorganic and Medicinal Chemistry. 2016 May;24(10):2242-2250. |
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2016-02 |
Multifunctional nanoparticles for oral protein drug delivery |
Nanomedicine: Nanotechnology, Biology and Medicine. 2016 Feb;12(2):463. |
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2015-09 |
Self-assembling bubble carriers for oral protein delivery |
Biomaterials. 2015 Sep;64:115-124. |
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2015-08 |
Novel Nrf2/ARE activator, trans-coniferylaldehyde, induces a HO-1-mediated defense mechanism through a dual p38alpha/MAPKAPK-2 and PK-N3 signaling pathway |
Chemical Research in Toxicology. 2015 Aug ;28(9):1681-1692. |
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2015-08 |
Zinc-dipicolylamine directed pharmaceutical delivery system (ZAPS) as an innovative cancer drug delivery platform |
Cancer Research. 2015 Aug;75(Suppl. 15):Abstract number 4413. |
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2015-08 |
Optimization of quinazoline-based kinase inhibitors: Identification of a dual FLT3/AURKA kinase inhibitor for the treatment of acute myeloid leukemia |
Abstracts of Papers of the American Chemical Society. 2015 Aug;250:Meeting Abstract 490. |
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2015-07 |
Identification of a potent 5-phenyl-thiazol-2-ylamine-based inhibitor of FLT3 with activity against drug resistance-conferring point mutations |
European Journal of Medicinal Chemistry. 2015 Jul;100:151-161. |
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2015-04 |
IL-1beta promotes malignant transformation and tumor aggressiveness in oral cancer |
Journal of Cellular Physiology. 2015 APR;230(4):875-884. |
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2015-03 |
Stem cell mobilizers targeting chemokine receptor CXCR4: Renoprotective application in acute kidney injury |
Journal of Medicinal Chemistry. 2015 Mar;58(5):2315-2325. |
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2014-11 |
Discovery of multiple kinases inhibitors, DBPR114, as the novel anti-cancer agent |
European Journal of Cancer. 2014 Nov;50(Suppl. 6):92-93. |
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2014-10 |
YYEI motif is critical to oncogenicity of 14-3-3 proteins |
Cancer Research. 2014 Oct;74(19 Suppl.):Abstract No. 3527. |
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2014-10 |
Novel irreversible EGFR tyrosine kinase inhibitor, DBPR112, as a therapeutic candidate for lung adenocarcinoma |
Cancer Research. 2014 Oct;74(19 Suppl.):Abstract No. 1756. |
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2014-08-15 |
Anticancer oral formulation |
JP5596680/2014-08-15 |
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2014-08-04 |
Effects of dipeptidyl peptidase-4 inhibition with MK-0431 on syngeneic mouse islet transplantation |
International Journal of Endocrinology. 2014 Aug 4;2014:Article ID 795283. |
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2014-06-04 |
抗癌口服制剂 |
CN102159541/2014-06-04 |
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