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日期	題名	關聯
2024-12	Alkoxylation of ketone mediated by N-heterocyclic carbene borane and sulfuric acid in alcohol	Asian Journal of Organic Chemistry. 2024 Dec;13(12):Article number e202400436.
2024-11-21	Discovery of a mu-opioid receptor modulator that in combination with morphinan antagonists induces analgesia	Cell Chemical Biology. 2024 Nov 21;31(11):1885-1898.e10.
2024-11	DBPR116, a prodrug of BPRMU191, in combination with naltrexone as a safer opioid analgesic than morphine via peripheral administration	Journal of Medicinal Chemistry. 2024 Nov 14;67(21):19777-19790.
2024-05-01	Thiazolidinone compounds and use thereof	EP3426246/2024-05-01
2023-11-15	Analysis of structure–activity relationship of indol-3-yl-N-phenylcarbamic amides as potent STING inhibitors	Bioorganic and Medicinal Chemistry. 2023 Nov 15;95:Article number 117502.
2023-10-05	A dual nociceptin and mu opioid receptor agonist exhibited robust antinociceptive effect with decreased side effects	European Journal of Medicinal Chemistry. 2023 Oct 05;258:Article number 115608.
2022-12-05	Benzo[b]thiophene-2-carboxamides as novel opioid receptor agonists with potent analgesic effect and reduced constipation	European Journal of Medicinal Chemistry. 2022 Dec 5;243:Article number 114728.
2022-11-22	オピオイド受容体調節因子及びその使用	JP7181536/2022-11-22
2022-11	Selective and antagonist-dependent µ-opioid receptor activation by the combination of 2-{[2-(6-chloro-3,4-dihydro-1(2H)-quinolinyl)-2-oxoethyl]sulfanyl}-5-phenyl-4,6-(1H,5H)-pyrimidinedione and naloxone/naltrexone	Bioorganic Chemistry. 2022 Nov;128:Article number 105905.
2022-08-30	チアゾリジノン化合物及びその使用	JP7132849/2022-08-30
2022-05-20	噻唑烷酮化合物及其用途	HK1258687/2022-05-20
2022-03-08	Opioid receptor modulators and use thereof	CA2996281/2022-03-08
2022-02-05	Discovery and development of a novel N-(3-bromophenyl)-{[(phenylcarbamoyl)amino]methyl}-N-hydroxythiophene-2-carboximidamide indoleamine 2,3-dioxygenase inhibitor using knowledge-based drug design	European Journal of Medicinal Chemistry. 2022 Feb 5;229:Article number 114043.
2022-01-19	噻唑烷酮化合物及其用途	J/005474/2022-01-19
2022-01-05	阿片受體調節劑及其用途	J/005174/2022-01-05
2021-09-28	噻唑烷酮化合物及其用途	CN108883099/2021-09-28
2021-09-24	阿片受體調節劑及其用途	HK1253294/2021-09-24
2021-07-22	Thiazolidinone compounds and use thereof	AU2017229129/2021-07-22
2021-06-04	阿片受体调节剂及其用途	CN108369222/2021-06-04
2020-11-18	Opioid receptor modulators and use thereof	EP3344997/2020-11-18
2020-10-08	Comparative study between deep learning and QSAR classifications for TNBC inhibitors and novel GPCR agonist discovery	Scientific Reports. 2020 Oct 8;10:Article number 16771.
2020-04-21	噻唑烷酮化合物及其用途	TWI691332/2020-04-21
2020-04	BPR1M97, a dual mu opioid receptor/nociceptin-orphanin FQ peptide receptor agonist, produces potent antinociceptive effects with safer properties than morphine	Neuropharmacology. 2020 Apr;166:Article number 107678.
2020-03-24	Tetrahydroisoquinolines for use as MOR/NOP dual agonists	US10597378/2020-03-24
2020-02-10	Unique sulfur-aromatic interactions contribute to the binding of potent imidazothiazole indoleamine 2,3-Dioxygenase inhibitors	Journal of Medicinal Chemistry. 2020 Feb 10;63(4):1642-1659.

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