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Showing items 51-100 of 231. (5 Page(s) Totally) << < 1 2 3 4 5 > >> View [10|25|50] records per page

Date	Title	Relation
2016-03	Disruption of protein-protein interactions: Hot spot detection, structure-based virtual screening and in vitro testing for the anti-cancer drug target survivin	RSC Advances. 2016 Mar;6(38):31947-31959.
2015-08	BPR2P001S0, a Coumarin derivative, induced cell cycle arrest in A549 through inhibiting PDPK1 activity	Cancer Research. 2015 Aug;75:Abstract number 1754.
2015-08	Optimization of quinazoline-based kinase inhibitors: Identification of a dual FLT3/AURKA kinase inhibitor for the treatment of acute myeloid leukemia	Abstracts of Papers of the American Chemical Society. 2015 Aug;250:Meeting Abstract 490.
2015-08	Optimization of furanopyrimidine-based kinase inhibitors: Identification of a BTK kinase inhibitor for the treatment of B cell lymphoma	Abstracts of Papers of the American Chemical Society. 2015 Aug;250:Meeting Abstract 180.
2015-08	Discovery of 2,4-diaminopyrimidines bearing a unique pharmacophore as anaplastic lymphoma kinase inhibitors	Abstracts of Papers of the American Chemical Society. 2015 Aug;250:Meeting Abstract 182.
2015-07-31	作為極光激酶抑制劑的稠合雙環嘧啶化合物	HK1151694/2015-07-31
2015-07-22	作为酪胺酸激酶抑制剂的稠合双环及多环嘧啶化合物	ZL200980144458.1/2015-07-22
2015-06-29	Homology modeling of DFG-in FMS-like tyrosine kinase 3 (FLT3) and structure-based virtual screening for inhibitor identification	Scientific Reports. 2015 Jun 29;5:Article number 11702.
2015-04-14	Fused multicyclic compounds as protein kinase inhibitors	US9006252B2/2015-04-14
2015-02	Function-oriented development of CXCR4 antagonists as selective human immunodeficiency virus (HIV)-1 entry inhibitors	Journal of Medicinal Chemistry. 2015 Feb;58(3):1452-1465.
2015-01	Identification of ligand efficient, fragment-like hits from an HTS library: Structure-based virtual screening and docking investigations of 2H- and 3H-pyrazolo tautomers for Aurora kinase A selectivity	Journal of Computer-Aided Molecular Design. 2015 Jan;29(1):89-100.
2014-12	BPR-3P0128 inhibits RNA-dependent RNA polymerase elongation and VPg uridylylation activities of Enterovirus 71	Antiviral Research. 2014 Dec;112:18-25.
2014-11	Discovery of multiple kinases inhibitors, DBPR114, as the novel anti-cancer agent	European Journal of Cancer. 2014 Nov;50(Suppl. 6):92-93.
2014-11	CDKN1A-mediated responsiveness of MLL-AF4-positive acute lymphoblastic leukemia to Aurora kinase-A inhibitors	European Journal of Cancer. 2014 Nov;50(Suppl. 6):19-20.
2014-10-29	作為極光激酶抑制劑的稠合雙環嘧啶化合物	ZL200980115577.4/2014-10-29
2014-10-21	化合物於製造治療病毒感染的藥物之用途	I457121/2014-10-21
2014-10	Small-molecule EGFR tyrosine kinase inhibitors for the treatment of cancer	Expert Opinion on Investigational Drugs. 2014 Oct;23(10):1333-1348.
2014-10	Optimization of 5,6-fused pyrimidine-based kinase inhibitors by computer-aided drug design for the treatment of AML	Cancer Research. 2014 Oct;74(19 Suppl.):Abstract No. 2530.
2014-10	Novel irreversible EGFR tyrosine kinase inhibitor, DBPR112, as a therapeutic candidate for lung adenocarcinoma	Cancer Research. 2014 Oct;74(19 Suppl.):Abstract No. 1756.
2014-08	CDKN1A-mediated responsiveness of MLL-AF4-positive acute lymphoblastic leukemia to Aurora kinase-A inhibitors	International Journal of Cancer. 2014 Aug;135(3):751-762.
2014-08	Ligand efficiency based approach for efficient virtual screening of compound libraries	European Journal of Medicinal Chemistry. 2014 Aug;83:226-235.
2014-07	Anaplastic lymphoma kinase (ALK) inhibitors: A review of design and discovery	MedChemComm. 2014 Jul;5(9):1266-1279.
2014-05	Facile identification of dual FLT3-Aurora A inhibitors: A computer-guided drug design approach	ChemMedChem. 2014 May;9(5):953-961.
2014-05	Cover Picture: Facile identification of dual FLT3–aurora a inhibitors: A computer-guided drug design approach (ChemMedChem 5/2014)	ChemMedChem. 2014 May;9(5):861.
2014-04-29	Quinoline compounds and their use for treating viral infection	US8710079B2/2014-04-29
2014-03-20	Fused bicyclic pyrimidine compounds as aurora kinase inhibitors	JP5502072/2014-03-20
2014-03	DBPR112, a potent and selective EGFR kinase inhibitor in preclinical study	Abstracts of Papers - American Chemical Society. 2014 Mar;247:Article number 315-MEDI.
2014-03	Efficient virtual screening using ligand efficiency based approach	Abstracts of Papers - American Chemical Society. 2014 Mar;247:Article number 55-MEDI.
2013-11-21	治療癌症的醫藥組成物	I415852/2013-11-21
2013-11	A development drug candidate targeting EGFR kinase for lung cancer: DBPR112	Journal of Thoracic Oncology. 2013 Nov;8(Suppl. 2):S779-S780.
2013-11	Peptide-mediated liposomal doxorubicin enhances drug delivery efficiency and therapeutic efficacy in lung cancer animal models	Journal of Thoracic Oncology. 2013 Nov;8(Suppl. 2):S779.
2013-10-01	喹啉化合物及包含其之治療病毒感染之醫藥組成物	I410245/2013-10-01
2013-09-22	A novel Aurora-A inhibitor, BPR1K0609S1, sensitizes colorectal tumor cells to 5-fluorofracil (5-FU) treatment [Erratum:International Journal of Biological Sciences. 2013 Apr 29;9(4):403-411]	International Journal of Biological Sciences. 2013 Sep 22;9(9):947.
2013-08-21	Fused multicyclic compounds as protein kinase inhibitors	EP2331530B1/2013-08-21
2013-08-13	Fused bicyclic and tricyclic pyrimidine compounds as tyrosine kinase inhibitors	US8507502B2/2013-08-13
2013-07-25	Pronounced induction of endoplasmic reticulum stress and tumor suppression by surfactant-free poly(lactic-co-glycolic acid) nanoparticles via modulation of the PI3K signaling pathway	International Journal of Nanomedicine. 2013 Jul 25;2013(8):2689-2707.
2013-07-01	做為蛋白質激酶抑制劑之稠合多環化合物	I400242/2013-07-01
2013-06-28	Optimization of ligand and lipophilic efficiency to identify an in vivo active furano-pyrimidine aurora kinase inhibitor	Journal of Medicinal Chemistry. 2013 Jun 28;56(13):5247-5260.
2013-06	An antimitotic and antivascular agent BPR0L075 overcomes multidrug resistance and induces mitotic catastrophe in paclitaxel-resistant ovarian cancer cells	PLoS ONE. 2013 Jun;8(6):Article number e65686.
2013-05	Aurora kinase inhibitors reveal mechanisms of HURP in nucleation of centrosomal and kinetochore microtubules	Proceedings of the National Academy of Sciences of the United States of America. 2013 May;110(19):E1779-E1787.
2013-05	Protein kinase inhibitor design by targeting the Asp-Phe-Gly (DFG) motif: The role of the DFG motif in the design of epidermal growth factor receptor inhibitors	Journal of Medicinal Chemistry. 2013 May;56(10):3889-3903.
2013-04-29	A novel Aurora-A inhibitor, BPR1K0609S1, sensitizes colorectal tumor cells to 5-fluorofracil (5-FU) treatment	International Journal of Biological Sciences. 2013 Apr 29;9(4):403-411.
2013-04-07	BPR000K, a novel Aurora kinase inhibitor	Abstracts of Papers - American Chemical Society. 2013 Apr 7;245:Article number 300-MEDI.
2013-04-07	Kinase-focused library: Design and synthesis of pyrimidines derivatives bearing amino substituents using high throughput parallel synthesis	Abstracts of Papers - American Chemical Society. 2013 Apr 7;245:Article number 298-MEDI
2013-04-07	3D-QSAR assisted drug design: Identification of a potent quinazoline based Aurora kinase inhibitor	Abstracts of Papers - American Chemical Society. 2013 Apr 7;245:Article number 87-MEDI.
2013-04-07	Development drug candidate targeting EGFR kinase: DBPR112	Abstracts of Papers - American Chemical Society. 2013 Apr 7;245:Article number 299-MEDI.
2013-04	Design and synthesis of Aurora kinase inhibitors as anticancer agents	Abstracts of Papers - American Chemical Society. 2013 Apr;245:Article number 301-MEDI.
2013-02-20	Parallel screening of Wild-Type and drug-resistant targets for anti-resistance neuraminidase inhibitors	PLoS ONE. 2013 Feb 20;8(2):Article number e56704.
2013-02-11	作為酪胺酸激酶抑制劑之稠合雙環及多環嘧啶化合物	I385174/2013-02-11
2013-01	3D-QSAR-assisted drug design: Identification of a potent quinazoline-based aurora kinase inhibitor	ChemMedChem. 2013 Jan;8(1):136-148.

Showing items 51-100 of 231. (5 Page(s) Totally) << < 1 2 3 4 5 > >> View [10|25|50] records per page